Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 5, Problem 5CHI
Summary Introduction
Generally, eukaryotic cells are larger than prokaryotic cells, such as bacteria and archaeal cells. Eukaryotes have complex structures and functions. They contain a nucleus and other membrane-bound organelles such as mitochondria, chloroplast, endoplasmic reticulum, Golgi apparatus, and lysosomes. Yeast, nematode worms, and mice are commonly used eukaryotic model organisms.
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Here we utilize a novel, well-characterized, endogenous mitochondrial mutation in the ATP6 gene of Drosophila melanogaster with a nearly complete loss of ATP synthase activity. These Drosophila mutants have a missense mutation in ATP6 (G to A transition resulting in a glycine to glutamate change at position 116 in the protein), the mitochondrial gene encoding subunit 6 of the F1Fo-ATP synthase(complex V of the respiratory chain. ATP6 allows for the hydrogen ion translocation required for the rotation of the Fo motor and the production of ATP from ADP. Drosophila ATP61 mutants model human mitochondrial encephalomyopathy and demonstrate phenotypes associated with degenerative disease, including: reduced longevity, mitochondrial pathology, progressive neural dysfunction, tissue degeneration and locomotor impairment.
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Chapter 5 Solutions
Prescott's Microbiology
Ch. 5.1 - MICRO INQUIRY In addition to separating each...Ch. 5.1 - Prob. 1RIACh. 5.1 - Retrieve, Infer, Apply 2. Why is the...Ch. 5.3 - MICRO INQUIRY Which cytoskeletal filament is made...Ch. 5.3 - Prob. 1RIACh. 5.3 - Prob. 2RIACh. 5.3 - Prob. 3RIACh. 5.4 - MICRO INQUIRY Why must proteins be unfolded when...Ch. 5.4 - Prob. 1RIACh. 5.4 - Retrieve, Infer, Apply What is a proteasome? Why...
Ch. 5.4 - Prob. 3RIACh. 5.4 - Prob. 4RIACh. 5.4 - Describe the secretory pathway. To what...Ch. 5.4 - Prob. 6RIACh. 5.5 - Prob. 1MICh. 5.5 - MICRO INQUIRY Which subunit attaches to the rough...Ch. 5.5 - Prob. 1RIACh. 5.5 - Retrieve, Infer, Apply Suggest an explanation for...Ch. 5.5 - Prob. 3RIACh. 5.5 - Prob. 4RIACh. 5.6 - Prob. 1MICh. 5.6 - Describe the structure of aerobic mitochondria,...Ch. 5.6 - Prob. 2RIACh. 5.6 - Prob. 3RIACh. 5.7 - Prepare and label a diagram showing the detailed...Ch. 5.7 - Prob. 2RIACh. 5.7 - How do the structure and mechanism of action of...Ch. 5.8 - Retrieve, Infer, Apply Outline the major...Ch. 5.8 - Retrieve, Infer, Apply What characteristics make...Ch. 5 - Discuss the statement: The most obvious difference...Ch. 5 - Bacterial and archaeal cell size is limited by the...Ch. 5 - Prob. 3CHICh. 5 - Compare the mechanisms by which most eukaryotic...Ch. 5 - Prob. 5CHI
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