Evolution
Evolution
4th Edition
ISBN: 9781605356051
Author: Douglas Futuyma, Mark Kirkpatrick
Publisher: SINAUER
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Chapter 5, Problem 2PDT
Summary Introduction

To explain: The effect of an advantageous allele at low frequency, and mutated allele, on the adaption of a large population.

Introduction: Adaptation is the changing in the behavior of an individual for surviving and accommodating the environment, whereas mutation is the change in the DNA sequence of an individual.

Summary Introduction

To explain: Whether both of the above events are accompanied by a selective sweep.

Introduction: Selective sweep is the result of natural selection where a beneficial but rare allele increases its frequency at a very faster rate and gets fixed in the population for their fitness.

Summary Introduction

To name: The detection method to study the variation in the DNA sequence near the locus after adaptation occurrence.

Introduction: In populations, variations occur because of different allelic frequencies and mutations. Both the events lead to adaptation and change the sequences of DNA near the locus of the allele. These variations in the sequences could be detected by different analysis methods.

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n class we investigated the reason cystic fibrosis is maintained in the human population in higher frequency than we expected given the deleterious effects of being homozygous at the CFTR gene. We calculated the actual mutation rate of the CFTR gene to be 6.7 x 10-7. The mutation rate expected under mutation-selection balance was 4 x 10-4. What is the most plausible explanation as to why cystic fibrosis is maintained in the human population at a higher frequency than we expect?   a. Negative selection against the CFTR deleterious alleles is too weak to eliminate the alleles from the human population.   b. Positive selection for the CFTR deleterious alleles is likely occurring in response to some other selective pressure in the human population, possibly resistance to typhoid fever.   c. The CFTR gene has an exceedingly low mutation rate causing humans to have no genetic variation at that gene.   d. The CFTR gene has an exceedingly high mutation rate and that is…
In class we investigated the reason cystic fibrosis is maintained in the human population in higher frequency than we expected given the deleterious effects of being homozygous at the CFTR gene. We calculated the actual mutation rate of the CFTR gene to be 6.7 x 10-7. The mutation rate expected under mutation-selection balance was 4 x 10-4. What is the most plausible explanation as to why cystic fibrosis is maintained in the human population at a higher frequency than we expect?   a. Negative selection against the CFTR deleterious alleles is too weak to eliminate the alleles from the human population.   b. Positive selection for the CFTR deleterious alleles is likely occurring in response to some other selective pressure in the human population, possibly resistance to typhoid fever.   c. The CFTR gene has an exceedingly low mutation rate causing humans to have no genetic variation at that gene.   d. The CFTR gene has an exceedingly high mutation rate and that is…
Suppose that in generation 0, the frequency of allele A1 in a population of armadillos is 0.4. In each generation, 10 percent of the individuals in that population are migrants from another population that has an allele frequency of 0.6. a) Calculate the frequency of A1 in each of the next two generations (generations 1 and 2). b) Is the change in allele frequency in generation 2 greater than, less than, or equal to the change in generation 1? How can you explain that answer? c) What will the allele frequency become in this population after many generations? I need all three parts with calculations asap!!
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