Anatomy & Physiology: An Integrative Approach
2nd Edition
ISBN: 9780078024283
Author: Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher: McGraw-Hill Education
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Chapter 3, Problem 4DYKB
ATP inhibits phosphofructokinase by binding to an allosteric site in glycolysis. ATP is functioning as a
- a. competitive inhibitor.
- b. competitive activator.
- c. noncompetitive inhibitor.
- d. noncompetitive activator.
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ATP inhibits glycolysis by binding to an allosteric site on the last enzyme In the pathway, thus ATP is a...
A. Competitive inhibitor
B. Noncompetitive inhibitor
C. Feedback inhibitor
D. More than one of these answers.
Please give the rationale as to why
One of the enzymes involved in glycolysis, aldolase, requires Zn2+ for catalysis. Under conditions of zinc deficiency and the enzyme lacks zinc, it would be referred to as the:
a. apoenzyme.
b. coenzyme.
c. holoenzyme.
d. prosthetic group.
e. substrate.
Which of the following statements concerning ATP synthesis is NOT true?
a.
The open conformation of the ATP synthase is for releasing ATP.
b.
The gamma subunit in the stalk responds to the flow of H+ and rotates the assembly counterclockwise and thus change the conformations of the active site to synthesize ATP.
c.
The tight conformation of the ATP synthase is for converting ADP and phosphate to ATP.
d.
The loose conformation of the ATP synthase is for binding ADP and phosphate.
e.
Ten protons are required to catalyze the rotation of the subunits so that one ATP is synthesized.
Clear my choice
Chapter 3 Solutions
Anatomy & Physiology: An Integrative Approach
Ch. 3.1 - Both the movement of Na+ down its concentration...Ch. 3.1 - Muscle contraction is an example of what form of...Ch. 3.1 - Prob. 3WDYLCh. 3.2 - Prob. 4WDYLCh. 3.2 - For a biochemical reaction that involves simple...Ch. 3.2 - What molecule is formed from exergonic reactions...Ch. 3.2 - Explain what occurs when the equilibrium is...Ch. 3.2 - Explain the effect a fever would have on chemical...Ch. 3.2 - What is the relationship of enzymes and activation...Ch. 3.3 - What is the active site of an enzyme and how does...
Ch. 3.3 - What is the mechanism of enzyme action, including...Ch. 3.3 - Explain how enzymes are generally named.Ch. 3.3 - How do changes in substrate concentration,...Ch. 3.3 - How are enzymes regulated through competitive and...Ch. 3.3 - Prob. 15WDYLCh. 3.3 - Prob. 16WDYLCh. 3.4 - Prob. 17WDYLCh. 3.4 - Prob. 18WDYLCh. 3.4 - Prob. 19WDYLCh. 3.4 - Prob. 20WDYLCh. 3.4 - Prob. 21WDYLCh. 3.4 - Prob. 22WDYLCh. 3.4 - Prob. 23WDYLCh. 3.4 - Prob. 24WDYLCh. 3.4 - Prob. 25WDYLCh. 3.4 - Prob. 26WDYLCh. 3.4 - Prob. 27WDYLCh. 3.4 - Prob. 28WDYLCh. 3 - Energy in ATP is used to power skeletal muscle...Ch. 3 - Prob. 2DYKBCh. 3 - Prob. 3DYKBCh. 3 - ATP inhibits phosphofructokinase by binding to an...Ch. 3 - All of the following are accurate about enzymes...Ch. 3 - Prob. 6DYKBCh. 3 - Prob. 7DYKBCh. 3 - All stages of cellular respiration are decreased...Ch. 3 - Prob. 9DYKBCh. 3 - Prob. 10DYKBCh. 3 - Prob. 11DYKBCh. 3 - Describe the different ways of classifying...Ch. 3 - Prob. 13DYKBCh. 3 - Describe the structure and mechanism of enzymes.Ch. 3 - Prob. 15DYKBCh. 3 - Prob. 16DYKBCh. 3 - In general terms, explain the fate of pyruvate if...Ch. 3 - Describe how oxygen becomes part of water during...Ch. 3 - Identify the source of carbon in carbon dioxide.Ch. 3 - Prob. 20DYKBCh. 3 - Prob. 1CALCh. 3 - Prob. 2CALCh. 3 - Another challenge to a patient with impaired...Ch. 3 - Prob. 4CALCh. 3 - Prob. 5CALCh. 3 - Prob. 1CSLCh. 3 - Prob. 2CSLCh. 3 - What occurs to the amount of product formed in a...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Rapidly dividing cells such as bone marrow, skin, intestinal mucosa, and cancer cells need DNA synthesis. In these cells, the following is observed: a. a decreased NADPH / NADP+ ratio b. increased flux through the oxidative reactions c. Flux through the oxidative reactions is low and the nonoxidative reactions are reversed to make ribose 5-phosphate. d. Ribose 5-phosphate is recycled through the oxidative steps via the nonoxidative reactions and gluconeogenesis. e. Ribose 5-phosphate is shunted into glycolysis by the nonoxidative reactions.arrow_forwardIn the first stage of glycolysis, the hydroxyl group on C6 of glucose is phosphorylated to form glucose-6-phosphate (G6P). In this reaction, which of the following statements is true? a. O b. d. e. Glucose kinase is used to catalyze the reaction. Hexokinase is used to catalyze the reaction. A molecule of NADH is synthesized. One ATP is synthesized. Fructose kinase is used to catalyze the reaction.arrow_forwardDefine the following terms: a. coenzyme b. anabolic pathway c. catabolic pathway d. signal transduction pathway e. glycolysisarrow_forward
- Which of the following statements is correct? a. Glycolysis and Krebs cycle produce ATP in substrate level phosphorylation b. Glycolysis and Krebs cycle produce ATP in oxidative level phosphorylation. c. Glycolysis and pyruvate oxidation produce ATP in substrate level phosphorylation. d. Glycolysis and pyruvate oxidation produce ATP in oxidative level phosphorylation.arrow_forwardGlycolysis is regulated primarily by _______________. a. three strongly exergonic, non-equilibrium reactions. b. three strongly endergonic, non-equilibrium reactions. c. allosteric effectors of pyruvate kinase. d. phosphorylation of phosphofructokinase. e. the availability of glucose-6-phosphate.arrow_forwardDoes the following inhibitors decrease ATP production or Blocks ATP production? a. DCCD b. FCCP c. Amytal d. Carboxin e. Cyanidearrow_forward
- Which of the following is incorrect about the ATP synthase mechanism? a. It explains how ATP is hydrolyzed into ADP and Pi b. At any moment, each catalytic site has a different conformation and binding affinity c. It is called the binding change mechanism d. It involves rotation-driven conformational changes that alter the affinity of each catalytic subunitarrow_forwardIdentify in which reactions in glycolysis the followingfunctions occur.a. ATP consumptionb. ATP synthesisc. NADH synthesisarrow_forwardATP production is limited from glycolysis in strenuously exercising muscle or when yeast are fermenting carbohydrates in closed vessels. The limiting factor is Select one: a. the increased acidity from lactic acid causing muscle damage b. the accumulation of CO, c. the lack of ATP to continue glycolysis d. the lack of organic fuel molecules to oxidize e. the need to regenerate NAD+arrow_forward
- You are testing the effects of different molecules on respiration using isolated liver cells that are growing on glucose. For each of the compounds listed below, indicate whether the compound will increase or decrease respiration (measured by monitoring oxygen consumption), and provide reasoning for your answer in two sentences at most. Consider only the early time after the compound begins to exert its effects. a. An inhibitor of the FoF1 ATPase b. A proton channel that enables protons to cross the inner mitochondrial membrane by facilitated diffusion c. An inhibitor of NADH dehydrogenase (complex I of the electron transport chain)arrow_forwardWhich of the following is FALSE about glycolysis? a. The pathway axidizes two moles of NADH to NAD* for each mole of glucose. b. The pathway requires two moles of ATP to get started catabolizing each mole of glucose. c. ADP is phosphorylated to ATP via substrate -level phosphorylation. d. The pattivay produces pyruvate as one of its products.arrow_forwardThe first reaction in glycolysis that results in the formation of an energy-rich compound (i.e., a compound whose hydrolysis or oxidation has a highly negative ΔG'°) is catalyzed by: a. glyceraldehyde 3-phosphate dehydrogenase. b. hexokinase. c. phosphofructokinase-1. d. phosphoglycerate kinase. e. triose phosphate isomerase.arrow_forward
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