Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 20, Problem 36P
Draw a separate hypothetical pedigree identifying the inbred individuals and the inbreeding pathways for each of the following inbreeding coefficients:
a.
b.
c.
d.
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Consider the following pedigree below for a rare autosomal trait. Be sure to take into account the inbreeding convention, when needed.
1. What is the probability that individual B is heterozygous?
2. What is the inbreeding coefficient of individual E?
3. After divorce, individual “A” decides to marry at random outside the pedigree. If the population allele frequency of the rare autosomal trait is 0.012, what are the chances of having an affected child for his first born of his second marriage?
A family pedigree is shown here.
A. What is the inbreeding coefficient for individual IV-3?
B. Based on the data shown in this pedigree, is individual IV-4 inbred?
3). The habitats of Florida panthers have been broken up by
freeways and other forms of development, leading to formation
of some small sub-populations where limited mate choices result
in inbreeding.
a. Consider the panther family pedigree shown here. What is the
inbreeding coefficient for the individual marked F at the bottom?
Annotate the pedigree to show how you got your answer.
(1/2)4 (1/2)5x2= (1/2)4= F
F?
b. If the frequency of a recessive disease susceptibility allele in
the general population of panthers to which the first generation in this pedigree belongs is 0.4, what is
the probability that the "F" individual will be susceptible?
2
c. What is the probability that an individual whose parents were not related is susceptible?
Chapter 20 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 20 - 20.1 Compare and contrast the terms in each of the...Ch. 20 - In a population, what is the consequence of...Ch. 20 - 20.3 Identify and describe the evolutionary forces...Ch. 20 - Describe how natural selection can produce...Ch. 20 - Thinking creatively about evolutionary mechanisms,...Ch. 20 - 20.6 Genetic drift, an evolutionary process...Ch. 20 - Over the course of many generations in a small...Ch. 20 - Catastrophic events such as loss of habitat,...Ch. 20 - 20.9 George Udny Yule was wrong in suggesting that...Ch. 20 - 20.10 The ability to taste the bitter compound...
Ch. 20 - Figure 20.6 illustrates the effect of an ethanol ...Ch. 20 - 20.12 Biologists have proposed that the use of...Ch. 20 - 20.13 Two populations of deer, one of them large...Ch. 20 - 20.14 Directional selection presents an apparent...Ch. 20 - 20.15 What is inbreeding depression? Why is...Ch. 20 - 20.16 Certain animal species, such as the...Ch. 20 - Genetic Analysis 20.1 predicts the number of...Ch. 20 - 20.18 In a population of rabbits, and . The...Ch. 20 - Sickle cell disease (SCD) is found in numerous...Ch. 20 - 20.20 Epidemiologic data on the population in the...Ch. 20 - The frequency of tasters and nontasters of PTC...Ch. 20 - Tay-Sachs disease is an autosomal recessive...Ch. 20 - 20.23 Cystic fibrosis (CF) is the most common...Ch. 20 - 20.24 In the mouse, Mus musculus, survival in...Ch. 20 - 20.25 In a population of flowers growing in a...Ch. 20 - Assume that the flower population described in the...Ch. 20 - 20.27 ABO blood type is examined in a Taiwanese...Ch. 20 - 20.28 A total ofmembers of a Central American...Ch. 20 - 20.29 A sample offield mice contains individuals...Ch. 20 - Prob. 30PCh. 20 - Albinism, an autosomal recessive trait...Ch. 20 - 20.32 The frequency of an autosomal recessive...Ch. 20 - 20.33 Evaluate the following pedigree, and answer...Ch. 20 - Evaluate the following pedigree, and answer the...Ch. 20 - The following is a partial pedigree of the British...Ch. 20 - Draw a separate hypothetical pedigree identifying...Ch. 20 - Prob. 37PCh. 20 - 20.38 Achromatopsia is a rare autosomal recessive...Ch. 20 - 20.39 New allopolyploid plant species can arise by...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- 4) Consider the pedigree below. Double lines indicate matings between related individuals: 2 F, 3 8 (9) 10 11 13 (14) (15) a) Calculate the inbreeding coefficient of individual 10 assuming none of their common ancestors are themselves inbred. b) Calculate the inbreeding coefficient of individual 15 assuming findividul = 0.05.arrow_forwardUsing the pedigree shown here, answer the following questions for individual VI-1. A. Is this individual inbred? B. If so, who is/are her parents’ common ancestor(s)? C. Calculate the inbreeding coefficient for VI-1. D. Are the parents of VI-1 inbred?arrow_forwardSnow geese (Chen caerulescens) come in two color types, white “snows” and “blues” with dark bodies. A single gene controls coloration, where the dark (“blue”) allele (D) is dominant. A population of 30,012 geese includes 9236 dark individuals. Genetic testing reveals that 7636 of the 9236 dark individuals are heterozygous (Dd). How many individuals are dd? A.) 7636 B.) 13140 C.) 1600 D.) 20776arrow_forward
- Assume a large population has two alleles, B and b, for a particular trait that displays a normal pattern of Mendelian inheritance. If 49% of the population displays the recessive phenotype for this trait.. a. What percent of the population would be heterozygous (Bf)? b. What percent of the population would be homozygous dominant (BB)? c. What percent of the population would display the dominant phenotype? d. What is the frequency of the recessive allele (b) expressed as a percentage? e. What is the frequency of the dominant allele (B) expressed as a percentage? Place the number in the space provided without any other symbols. MEarrow_forwardFrom the pedigree shown here, answer the following questions with regard to individual VII-1. A. Who are the common ancestors of her parents? B. What is the inbreeding coefficient for this individual?arrow_forwardWhich of the following applies to the Hardy-Weinberg expression:p2 + 2pq + q2?a. Knowing either p2 or q2, you can calculate all the otherfrequencies.b. It applies to Mendelian traits that are controlled by one pairof alleles.c. 2pq = heterozygous individualsd. It can be used to determine the genotype and allelefrequencies of the previous and the next generations.e. All of these are correct.arrow_forward
- Consider the following pedigree below for a rare autosomal trait. Be sure to take into account the inbreeding convention, when needed. What is the inbreeding coefficient of individual E?arrow_forwardThe equation p + 2pq + q = 1 representing the Hardy-Weinberg proportions examines genes with only two alleles in a population. a. Derive a similar equation describing the equilib- rium proportions of genotypes for a gene with three alleles. [Hint: Remember that the Hardy- Weinberg equation can be written as the binomial expansion (p + q)*.] b. A single gene with three alleles (r, 1", and i) is responsible for the ABO blood groups. Individuals with blood type A can be either A or ^ i; those with blood type B can be either /* 1 or * i; people with AB blood are r*, and type O individuals are ii. Among Armenians, the frequency of ^ is 0.360, the frequency of 1 is 0.104, and the frequency of i is 0.536. Calculate the frequencies of individuals in this population with the four possible blood types, assuming Hardy-Weinberg equilibrium. %3Darrow_forwardIn a wild strain of tomato plants, the phenotypic variance fortomato weight is 3.2 g2. In another strain of highly inbred tomatoesraised under the same environmental conditions, the phenotypicvariance is 2.2 g2. With regard to the wild strain,A. Estimate VG.B. What is hB2?C. Assuming that all of the genetic variance is additive, what is hN2?arrow_forward
- Identify each of the following as an example of allele, genotype,and/or phenotype frequency:A. Approximately 1 in 2500 individuals of Northern Europeandescent is born with cystic fibrosis.B. The percentage of carriers of the sickle cell allele in WestAfrica is approximately 13%.C. The number of new mutations per generation resultingin achondroplasia, a genetic disorder, is approximately5 × 10−5.arrow_forwardThe equation p2+ 2pq + q2= 1 representing theHardy-Weinberg proportions examines genes withonly two alleles in a population.a. Derive a similar equation describing the equilibrium proportions of genotypes for a gene withthree alleles. [Hint: Remember that the HardyWeinberg equation can be written as the binomialexpansion (p + q)2.]b. A single gene with three alleles (IA, IB, and i) isresponsible for the ABO blood groups. Individualswith blood type A can be either IA IAor IA i;those with blood type B can be either IB IBor IB i;people with AB blood are IA IB, and type O individuals are ii. Among Armenians, the frequency of IAis0.360, the frequency of IBis 0.104, and the frequencyof i is 0.536. Calculate the frequencies of individuals in this population with the four possible bloodtypes, assuming Hardy-Weinberg equilibrium.In Problems 15–17, you will see that because matingbetween individuals within populations at Hardy-Weinbergequilibrium is random, it is possible to predict…arrow_forwardCystic fibrosis (CF) is a recessive autosomal disorder. In certain populations of Northern European descent, the number of people born with this disorder is about 1 in 2500. Assuming Hardy- Weinberg equilibrium for this trait: A. What are the frequencies for the normal and CF alleles? B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals? C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates?arrow_forward
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