Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 19, Problem 21P
Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Metabolizing a fatty acid via the B-oxidation pathway will generate acetyl CoA, NADH
and FADH₂.
Based on your biochemical knowledge, the major metabolic intermediate will enter
cellular respiration in [Select]
and the reduced coenzymes
will enter cellular respiration in [Select]
Could a mature red blood cell perform the ß-oxidation pathway?
Yes, in their cytoplasm.
Give an account of β – oxidation of saturated even carbon fatty acid (Palmitic acid)along with the total ATPs obtained.
Calculate the number of ATPS generated from the metabolic oxi-
dation of the four carbons of acetoacetyl-CoA to CO,. Now
consider the homolog derived from oxidation of an odd-numbered
carbon chain, namely propionoacetyl-CoA. Calculate the net ATP
yield from oxidation of the five carbons of this compound to CO,.
Chapter 19 Solutions
Biochemistry
Ch. 19 - Radiolabeling with 14C-Glutamate Describe the...Ch. 19 - Prob. 2PCh. 19 - Assessing the Effect of Active-Site...Ch. 19 - Understanding the Mechanism of the -Ketoglutarate...Ch. 19 - Understanding the Action of Fluoroacetate on the...Ch. 19 - Prob. 6PCh. 19 - Prob. 7PCh. 19 - Prob. 8PCh. 19 - Prob. 9PCh. 19 - Prob. 10P
Ch. 19 - Prob. 11PCh. 19 - Prob. 12PCh. 19 - Prob. 13PCh. 19 - Prob. 14PCh. 19 - Prob. 15PCh. 19 - Prob. 16PCh. 19 - Understanding the Oxidation of Glucose and Its...Ch. 19 - Prob. 18PCh. 19 - Prob. 19PCh. 19 - Prob. 20PCh. 19 - Complete oxidation of a 16-carbon fatty acid can...Ch. 19 - Study Figure 19.18 and decide which of the...Ch. 19 - Prob. 23P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.arrow_forwardCalculate the number of ATP formed from NADH and FADH2. The calculation should be based on the total number of protons and c-subunits of 2-Acetyl-CoA that has 15 subunits.arrow_forwardCells often use the same enzyme reaction pattern for analogous metabolic conversions. For example, the steps in the oxidation of pyruvate to acetyl-CoA and of a-ketoglutarate to succinyl-CoA, although catalyzed by different enzymes, are very similar. The first stage of fatty acid oxidation follows a reaction sequence closely resembling a sequence in the citric acid cycle. Use equations to show the analogous reaction sequences in the two pathways.arrow_forward
- The citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in red). Identify which of the carbons in each intermediate will be labeled in the first round of the cycle by selecting the indicated carbon(s). Each question has multiple options, please choose more than one. Which carbon(s) in α‑ketoglutarate will contain C14? 1 2 3 4 5 Which carbon(s) in succinyl‑CoA will contain C14? 1 2 3 4 Which carbon(s) in succinate will contain C14? 1 2 3 4 Which carbon(s) in fumarate will contain C14? 1 2 3 4 Which carbon(s) in malate will contain C14? 1 2 3 4 Which carbon(s) in oxaloacetate will contain C14? 1 2 3 4arrow_forwardActivation of the fatty acid (converting it to fatty acyl-SCoA) requires the expenditure of 2 ATPs. Use your answers from parts B and C to calculate the total number of ATPs generated from the metabolism of a saturated fatty acid with 18 carbon atoms including both the citric acid cycle and the ββbeta-oxidation pathway as well as the initial ATP required to produce the acyl-SCoA molecule that starts the process. Express your answer as an integer.arrow_forwardupon digestion of starch maltose, one of its degradation products is further hydrolyzed into its monosaccharide components prior to intestinal absorption and entry into the glycolysis. calculate the number of ATP molecules produced from the digestion and complete oxidation of 1 molecule of maltose considering the glycerol-3-phosphate shuttle. question: 5. what is the total number of acetyl CoA molecules entering the citric acid cyclearrow_forward
- Consider a 24:1 △cis-9 fatty acid in the mitochondrion. For each fatty acid given, determine the following. 1. Gross ATP from b-oxidation cycles 2. Gross ATP from acetyl CoA produced 3. Gross ATP from conversion of propionyl CoA (if applicable) 4. Total number of ATP deducted 5. Total net ATParrow_forwardFatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.arrow_forwardPart A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodiesarrow_forward
- Take a look at the citric acid cycle. Look at the entry of acetyl CoA as the first step and oxaloacetate as the final. Determine each absorbed amino acid's probable point of entrance in the cycle and indicate the stoichiometric quantity of the citric acid cycle intermediate or starting material generated per oligopeptide molecule. If an amino acid has many entrance points into the cycle, you may choose any of them as long as stoichiometric connections are maintained.arrow_forwardThe conversion of pyruvate to Acetyl-CoA involves an oxidative decarboxylation. Correct the path of the electrons through this mechanism: Pyruvate -> NAD -> lipoamide -> FAD -> TPParrow_forwardFatty acid biosynthesis begins with the condensation of a two-carbon acetyl residue from acetyl-COA and oxaloacetate, while oxidation leads to the release of two carbon units, acetyl-CoA and fatty acyl-CoA. However, these two processes are not simple reversal. Compare and contrast these two pathways.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY