Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 19, Problem 14P
Interpretation Introduction
Interpretation:
The mechanism of malate synthase reaction and the role of CoA in this reaction should be determined.
Concept Introduction:
Within enzymology, malate synthesis is known as an enzyme which is used to catalyze the below reactions:
Acetyl-CoA, glyoxylate and H2O are the recognized as the three substrates of this reaction and CoA and malate are the two products.
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Considering the complete oxidation of an 18-C fatty acid. Give the answer to the following question.a. What is the total number of NADH produced in TCA if all of the acetyl CoA enters the cycle?
b. What is the total number of FADH2 produced in TCA if all the acetyl CoA enters the cycle?c. How much ATP is produced in the overall oxidation?
25. The AG" values for the two reactions are given.
1.
2.
oxaloacetate + acetyl-CoA + H₂O → citrate + COASH
oxaloacetate + acetate → citrate
Enzymes for reactions 1 and 2 are citrate synthase and citrate lyase, respectively.
Determine the AG" for the hydrolysis of acetyl-CoA
acetyl-CoA + H₂O
acetate + COASH + H+
plane een isoimorfbold bns
(94) opg
Vp1903 9911
AG¹⁰ ?
AGO = -32.2 kJ/mol
AG"=-1.9 kJ/mol
Chapter 19 Solutions
Biochemistry
Ch. 19 - Radiolabeling with 14C-Glutamate Describe the...Ch. 19 - Prob. 2PCh. 19 - Assessing the Effect of Active-Site...Ch. 19 - Understanding the Mechanism of the -Ketoglutarate...Ch. 19 - Understanding the Action of Fluoroacetate on the...Ch. 19 - Prob. 6PCh. 19 - Prob. 7PCh. 19 - Prob. 8PCh. 19 - Prob. 9PCh. 19 - Prob. 10P
Ch. 19 - Prob. 11PCh. 19 - Prob. 12PCh. 19 - Prob. 13PCh. 19 - Prob. 14PCh. 19 - Prob. 15PCh. 19 - Prob. 16PCh. 19 - Understanding the Oxidation of Glucose and Its...Ch. 19 - Prob. 18PCh. 19 - Prob. 19PCh. 19 - Prob. 20PCh. 19 - Complete oxidation of a 16-carbon fatty acid can...Ch. 19 - Study Figure 19.18 and decide which of the...Ch. 19 - Prob. 23P
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