Q: Describe the concepts behind the main types of immunoassays,and discuss their uses in diagnosis.
A: Immunoassay techniques allow rapid and accurate measurement or trace antigen and antibody. They use…
Q: What is immunoassay? Differentiate direct and indirect immunoasay tests.
A: In immunology, antigen (Ag) refers to any particle or object that is capable of elucidating immune…
Q: How would you measure deamidation in a monoclonal antibody?
A: A monoclonal antibody (mAb or moAb) is an antibody made up of a particular white blood cell. All…
Q: What is the purpose of anti-human IgG antibodies in immunological testing?
A: Each IgG is composed of four peptide chains with two antigen binding sites - two γ-class heavy…
Q: explain the reason behind developing different forms of Monoclonal antibodies (chimeric MABs,…
A: Monoclonal antibody : Monoclonal antibody is an antibody which is made by cloning the white blood…
Q: What are the findings on immunology? and What is helpful about immunology, the branch of medicine…
A: Immunology is the study of the immune system in all of its facets, including its structure and…
Q: Describe the procedures for an ELISA test for the HIV antibodies in patients
A: HIV an influenza virus enters the cell by using endocytosis procedure. HIV is called as human…
Q: What is the cancer cell line name used in hybridoma technology?
A: Hybridoma technology may be a technique for manufacturing massive numbers of identical antibodies.…
Q: Define specificity and sensitivity as these terms relate to immunological testing.
A: Immunological tests employ an artificial antigen or antibody to detect the presence of an antibody…
Q: What are five commercially available immunodiagnostic kits?
A: Five commercially available immunodiagnostic kits are as follows : 1)HIV CheX: It is an ELISA pack…
Q: What is the purpose and importance of the Immunology-Serology section in the laboratory?
A: Serum is the fluid and solute component of blood which does not play a role in clotting.
Q: What are passive andactive immunization?According to the duration ofthe protection how do thesetypes…
A: The immunology is a branch of science that studies and deals with the immune system of the body. The…
Q: If 0.9 ml. of a vaccine contains 1595 units of antigen, how many units would be present in each…
A: The antigen is referred to as the substance that is principally accountable for generating an immune…
Q: Explain the differences between direct and indirect procedures inimmunoassay tests, giving examples.
A: Immunoassays are biochemical test based on antigen-antibody interactions. It is used to determine…
Q: What is the principle of Immunochromatographic system, and its uses? Long answer please
A: Answer: CHROMATOGRAPHY TECHNIQUE = It is the technique which is used to separate the components of a…
Q: Homogeneous Immunoassay (HIA) Application
A: Homogeneous ImmunoAssay: It is a biochemical test that evaluates the presence or concentration of a…
Q: Why do you think defibrnated blood is commonly used as the representative of blood sample in most…
A: The blood possesses an insoluble protein called fibrin, which is formed from fibrinogen produced by…
Q: Describe the term serology and explain the immunologic principle behind serological tests.
A: Immune reactions to antigens result in the production of antibodies, and antibodies strongly attach…
Q: When a patient goes from testing negative for a specific antibody to testing positive a month later…
A: An antibody or serology test is a blood test that looks for signs of a previous infection. It…
Q: hat Is Immuno Electrophoresis?
A: A complicated network of cells, tissues, organs, and the substances they produce that aids in the…
Q: What are natural activeimmunization and artificialactive immunization?
A: Immunity refers to every mechanism of the body that helps to protect the body from harmful foreign…
Q: Which of the following is NOT TRUE about immunological tests? Question 2 options: A Antibodies…
A:
Q: What are the advantages/disadvantages of using a direct immunoblotting method? Compare and contrast…
A: Immunoblotting (western blotting) techniques are a rapid and highly sensitive method for the…
Q: Discuss the principles and concepts of the following: a. Auto technician / Tissue Processing b.…
A: Since each part needs a comprehensive explanation, process steps and each question is unrelated,…
Q: Which of the following best describes an attenuated whole-agent vaccine? Which option is the…
A: Ans ✓Inactivated toxin (toxoid) that induces immunity against microbial toxin.This is the correct…
Q: Describe the two immunological diagnostic techniques that rely on a secondary antibody and explain…
A: Protein molecules known as antibodies or immunoglobulins are created by the body's immune cells.…
Q: The first antibody used in an immunoassay to detect the foreign particle antigen enzyme…
A: Detection of a specific protein can be done by immunoassay techniques. The specific proteins that…
Q: What is immunoassay, avidity and specificity
A: Immunoassay are the bioanalytical methods that use the specificity of an antigen-antibody reaction…
Q: Why are primary immunodeficiencies considered “experiments ofnature”?
A: Immunodeficiency is a state in which the immune system’s ability to fight infectious disease and…
Q: Describe an ELISA test to detect the presence of HIV antibodies in a patient.
A: HIV is a virus than can cause AIDS if not treated .ELISA is the one of the test to screen HIV .…
Q: What is a screening test? Immunoassay Enzyme immunoassay (EAI) Enzyme-multiplied immunoassay…
A: Note - we are supposed to answer only three subparts of a question. Please repost other questions…
Q: Using flow diagrams show the main steps in antigen and antibody detection ELISA's.
A:
Q: Define the term serology, and explain the immunologic principle behind serological tests.
A: An antigen is a substance or a molecule that the body recognizes as a foreign particle. That means…
Q: How does immunoparasitology help in designing vaccines and drugs
A: Immunoparasitology is a science of biology which deals with the immune parasite relationship. It…
Q: What is the process in which antibodies attach to antigens, causing the formation of masses of…
A: Because the Y-shaped antibody arms randomly attach to many surfaces of non-self red blood cells,…
Q: What is the working principle of Lateral flowimmunochromatographic assays (LFIAs)? Supported with a…
A: We are giving answers only but we don't provide references. For a wide range of target analytes,…
Q: Method: 1. 96 well plates are coated with an antigen. Sites unoccupied by the antigen are blocked…
A: We know that enzyme linked immunosorbent assays are sensitive technique that use an enzyme Ab-Ag…
Q: Example of 5 commercially active immunodiagnostic test kits
A: Immuno-diagnostic assays are procedures that utilize products of the immune response as the integral…
Q: What is the principle of Immunochromatographic system, and its uses?
A: Immunology is the branch of science that deals with the study of immune systems and their…
Q: Why monoclonal antibodies method is better than polyclonal antibodies method in detecting specific…
A: Answer: Introduction: Monoclonal antibodies (mAbs) are formed by presenting an antigen to a mouse…
Q: Describe 2 methods of immunotherapy currently in use, and the clinical results of one of these (ie,…
A: Immunotherapy is a theraputic approach by which we makecan use of the concepts of immunology to…
Q: Discuss the principles and concepts of the following: a. Auto technician / Tissue Processing b.…
A: Histology is defined as the study of tissues and its structure. Since structure is always related to…
Q: The process where antibody attracts macrophages to invading microbes by making them more appealing…
A: Macrophages are the part of Innate immunity system. These phagocytose bacteria and secrete both…
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- What is the working principle of Lateral flowimmunochromatographic assays (LFIAs)? Supported with a figure and reference plzWhat are the important considerations that you have to remember in antibody screening? What are the important considerations that you have to remember in antibody identification What is the role of antibody screening in pretransfusion compatibility testing?You just received the properly labeled blood bank specimen on patient Aran Stark. You decide to collect some background information about her known historical antibodies before beginning the work-up knowing that she has a history of anti-E, anti-K, anti-Jk^a, anti-Fy^a, anti-M and anti-Le^a. Which antibody can be neutralized? Which antibody is destroyed with 0.2M DTT treatment? Which antibody reactivity is enhanced by acidification? Which of the antibodies that are typically IgG in nature are destroyed by enzymes? Which are enhanced by enzymes? Which of these antibodies have been known to cause hemolytic transfusion reaction? Which of these antibodies are known to react at room temperature? Which of these antibodies react best at 37C? * When you complete the work-up, you note that the anti-Jk^a antibody is no longer detectable. Can the patient receive red blood cells that contain the Jk^a antigen? Why or why not?
- What do you mean by immunofluorescenceDescribe 2 methods of immunotherapy currently in use, and the clinical results of one of these (ie, how often does it work well?)What is a screening test? Immunoassay Enzyme immunoassay (EAI) Enzyme-multiplied immunoassay technique (EMIT) Fluorescence polarization Radioimmunoassay (RIA) Chromatography Thin-layer chromatography (TLC) Gas chromatography (GC) Liquid chromatography (LC) (i.e, high performance liquid chromatography or HPLC) What is a confirmatory test? Hyphenated technique. Combination of two sophisticated technologies (I.e., Gas Chromatography - mass spectrometry or GC-MS) or other modern and acceptable techniques (l.e., LC-MS, GC-MS-MS, or LC-MS-MS).
- You are an oncologist at a local medical center and you have 3 patients with various types of lung cancer. You evaluate the cell surface markers of the cancer cells from each patient using a technique called immunohistochemistry. Which of the following patients is most likely to respond to immunotherapy (i.e. the immunotherapy is likely to work to target cancer cells)? Patient 1: PDL-1 is 0% Patient 2: PDL-1 is 10% Patient 3: PDL-1 is 20%You just received the properly labeled blood bank specimen on patient Aran Stark. You decide to collect some background information about her known historical antibodies before beginning the work-up knowing that she has a history of anti-E, anti-K, anti-Jk^a, anti-Fy^a, anti-M and anti-Le^a. Which of these antibodies have been known to cause hemolytic transfusion reaction?What is the purpose of anti-human IgG antibodies in immunological testing?