(Theme 5) You are studying the role of a gene called stop. When expressed, stop appears to inhibit cellular processes controlled by another gene, Bisc219. To probe the molecular mechanism of stoP-mediated regulation of Bisc219, you begin by assaying bisc219 expression at the mRNA and protein levels. Your results are shown below. long short bisc219 mRNA stop no stop expressed | | long short Bisc219 protein stop no stop expressed a) Propose and briefly explain a specific molecular mechanism through which stop could operate, assuming that stop encodes a small RNA. Your answer should specify a specific molecular interaction(s) involved in gene expression that is/are disrupted. b) Propose and briefly explain a different molecular mechanism through which stop operates, now assuming that stop encodes a protein.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Please answer parts a and b as shown in the image

(Theme 5) You are studying the role of a gene called stop. When expressed,
stop appears to inhibit cellular processes controlled by another gene,
Bisc219. To probe the molecular mechanism of stoP-mediated regulation of
Bisc219, you begin by assaying bisc219 expression at the mRNA and protein
levels. Your results are shown below.
long
short
bisc219 mRNA
stop
no stop expressed
long
short
Bisc219 protein
stop
no stop expressed
a) Propose and briefly explain a specific molecular mechanism through
which stop could operate, assuming that stop encodes a small RNA. Your
answer should specify a specific molecular interaction(s) involved in gene
expression that is/are disrupted.
b) Propose and briefly explain a different molecular mechanism through
which stop operates, now assuming that stop encodes a protein.
Transcribed Image Text:(Theme 5) You are studying the role of a gene called stop. When expressed, stop appears to inhibit cellular processes controlled by another gene, Bisc219. To probe the molecular mechanism of stoP-mediated regulation of Bisc219, you begin by assaying bisc219 expression at the mRNA and protein levels. Your results are shown below. long short bisc219 mRNA stop no stop expressed long short Bisc219 protein stop no stop expressed a) Propose and briefly explain a specific molecular mechanism through which stop could operate, assuming that stop encodes a small RNA. Your answer should specify a specific molecular interaction(s) involved in gene expression that is/are disrupted. b) Propose and briefly explain a different molecular mechanism through which stop operates, now assuming that stop encodes a protein.
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