Discuss the principles and applications of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in molecular diagnostics.
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Discuss the principles and applications of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in molecular diagnostics.
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- Explain this approach: matrix-assisted laser desorption ionization (MALDI) ?Discuss SSD (non-isocentric) technique and SAD (isocentric) technique including the advantages and disadvantages of each type of setup.Name two radioisotopes used within the medical imaging processes, one administered by inhalation and one used by intravenous injection. For both of these radioisotopes, what are their half-life and what is the relevance of that to why it is used? What are both of these specific use in diagnostic imaging?What are they treating?
- Provide two advantages and two disadvantage of flow cytometry analysis. Briefly explain each.Discuss in chemical detail the mechanism of action (how it works) of IMAC. Compare and contrast gel filtration chromotography with IMAC. Discuss the pros and cons for each technique. Why would a scientist prefer one technique over another? In what situations would one technique be more viable than the other?Explain why radiopharmaceuticals cannot be used interchangeably with other contrast agents in medical imaging.
- Answer this ff question: 1. Explain the importance of system suitability on HPLC method of analysis. 2.In UV and visible spectrophotometry, the specimen is generally dissolved in a solvent, and determinations are made at room temperature using a path length of 1 cm. Give the most common solvents suitable for UV or visible spectrophotometry.Patch clamp What is patch clamp technique? Identify two features of the patch clamp technique that make it a useful tool in studying cellular electrophysiology. Explain each thoroughly. What is the role of the reference electrode in the patch clamp technique? Discuss how it works.Label the key components of a matrix-assisted laser desorption/ionization time-of-flight, or MALDI-TOF, mass spectrometer. ion source matrix laser Answer Bank detector transient recorder Beam splitter Trigger flight tube O protein sample
- The basic component of a fluoroscopic x-ray system suitable for interventional procedures consist of a generator,x-ray tube and housing including collimator and filtration,patient table,anti-scatter grid and an image receptor.Describe the key design features and function of each of these component and briefly discuss the role of automatic brightness controlDo not include zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed dosages will vary factors. A medication label for an antibiotic has the following instructions for reconstitution: Amount of Diluent 20 mL 10 mL 4 mL 1.8 mL Order: 500,000 units IM stat Reconstitute with Type here to search Esc Concentration 50,000 units per mL of solution 100,000 units per mL of solution 250,000 units per mL of solution 500,000 units per mL of solution Moving to another question will save this response. diluent for a concentration of F2 F3 # O # F4 • F5 $ per mL. % F6 9 DELL F7Briefly compare the following test systems, Micro-tox, ATP-Tox, and Daphnia magna IQ test . Explain how each assay works (the principle), not the test procedure.
