Describe the probable effect in adipocytes of insulin-stimulated uptake of glucose into these cells.
Q: List the disadvantages of insulin obtained from the pancreas of salughtered cows and pigs:
A: Insulin is a peptide hormone, which is secreted by the beta cells of islets of Langerhans of the…
Q: Describe the mechanism of action of insulin. Based on the MOA, when would insulin be…
A: Insulin is a major factor in the regulation of intermediate metabolism, and its overall function is…
Q: The combined effects of exercise- released catacholamines on insulin and glucagon production are O…
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A: Hormones are chemical messengers that are involved in signaling pathways. They regulate many…
Q: With regard to diabetes, exercise increases the insulin sensitivity of people who are insulin…
A: Diabetes is a metabolic condition in which the body is not able to utilize the glucose produced from…
Q: Which of the following statements about insulin is not true? a. The insulin receptor has tyrosine…
A: Insulin is a peptide hormone produced by beta cells of the pancreatic islets.
Q: Fatty acids appear to stimulate insulin secretion to a much greater extent when glucose is also…
A: Long chain fatty acids potentiate glucose stimulated insulin secretion. Fatty acids don't trigger…
Q: c) Briefly explain why insulin treatment did not yield a continuous high rate of glucose uptake.
A: There are several mechanisms that can explain why insulin treatment did not yield continuous high…
Q: Describe the mechanism of action of insulin and glucagon, and how they differ in relation to the…
A: Blood glucose level or blood glucose concentration can be described as the concentration or the…
Q: Match the molecule involved in insulin signaling with what it does insulin receptor binds to insulin…
A: Insulin pathway is very important for the body to maintain glucose levels in the muscles and fat…
Q: antagonistic Hormone Explain why insulin and glucagon are considered antagonistic hormones?
A: The blood sugar level in human beings is controlled by the antagonistic action of insulin and…
Q: Contrast the roles of insulin and glucagon in regulating blood glucose levels.
A: The role of the insulin and the glucagon is in regulating the blood glucose level. The blood glucose…
Q: Because the prime early symptom of diabetes is a high levelof blood glucose, insulin is often…
A: Diabetes is a lifestyle disorder associated with an imbalance in the concentration of glucose in the…
Q: Visceral fat loss is often associated with increased insulin sensitivity. Assuming that with the…
A: D. -10.6
Q: Describe the effects of insulin and glucagon on bloodglucose.
A: Insulin and glucagon are peptide hormones that are produced by the beta and alpha cells of the…
Q: Discuss and trace the pathway of the production of insulin, starting from the stimulation by…
A: Insulin is a peptide hormones, which plays a major role in the regulation of the glucose…
Q: In patients with type 2 diabetes, cells no longer respond to the hormone insulin. What change has…
A: Type 2 diabetes is a medical condition where that affects the way the body processes blood sugar…
Q: Describe the effects of The effect on the glucagon response in the liver treated with a cAMP…
A: Glucagon Response in liver: The role of glucagon in the body is to control the blood glucose levels…
Q: Ketoacidosis is a common feature of insulin-dependent diabetes mellitus, but not of…
A: Glucose is catabolized in the body to generate energy in the form of ATP. In the absence of glucose…
Q: Mechanism of sulphonylureas’ action includes: A. Stimulation beta cells to secrete insulinB.…
A: Sulfonylureas are a class of organic compounds used in medicine and agriculture, e.g. as…
Q: Please provide the metabolic reasons for why a person with diabetes mellitus would exhibit higher…
A: Diabetes mellitus is a condition that is characterized by elevated levels of glucose in the blood.…
Q: Extreme thirst is a characteristic symptom of diabetes.Explain.
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Q: Diabetic Ketoacidosis is rare in type 2 diabetes due to the increased production of which hormone? O…
A: Type II diabetes is mostly caused due to a bad lifestyle.
Q: Name two proteins that are effectors of the insulin signaling pathway in adipocytes, liver, or…
A: Insulin is the only known hormone that is known to lower the blood glucose levels in our body. The…
Q: Type 1 diabetes is caused by the destruction of _____________.
A: Diabetes mellitus or commonly known as diabetes is a group of metabolic disorders that is…
Q: Discuss the mechanism of action of insulin in maintaining the homeostasis of blood sugar in a normal…
A: Homeostasis is the condition wherein a steady chemical, physical, and internal state of the living…
Q: All of the following increase insulin secretion/production EXCEPT: Select one or more: O a.…
A: All of the following increases insulin secretion except.
Q: Insulin stimulated glucose uptake takes place in all of the following except-
A: Insulin stimulates glucose uptake with the help of GLUT 4 transporter which is translocated from…
Q: B. What minimum concentration of insulin would be required to result in 99% of the receptors having…
A: Insulin is a hormone synthesized exclusively by the pancreatic beta cells. These beta cells are…
Q: Explain the difference in terms of pancreas function between insulin-dependent and…
A: It is required to explain the difference in terms of function of pancreas between insulin-dependent…
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Q: TRUE or FALSE: Type 2 diabetes is a ketosis-resistant, adult-onset diabetes that always require…
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Q: Describe one insulin-mediated mechanism that normally increases glucose uptake into skeletal muscle…
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Q: . In uncontrolled diabetes, levels of hydrogen ions are elevated. Explain how these ions are…
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A: Insulin is an example of a hormone whose receptor is a tyrosine kinase. The hormone binds to domains…
Q: a) what hormone is high scereted in this condition? b) what is the possible cause of this discase?…
A: Hyperinsulinism (HI) is the most common cause of both short-term and permanent disorders of…
Q: Discuss, in terms of AMPK activity and GLUT4, how physical inactivity might lead to insulin…
A: The hormone insulin is considered as the peptide hormone, which helps to uptake the glucose from the…
Q: Hyperinsulinism, the result of an excessive insulin dose or an insulin-secreting tumor, can result…
A: Glucose is catabolized to generate energy in the body. Glucose is stored as a glycogen polymer, and…
Q: Insulin stimulated glucose uptake takes place in all of the following except- 1. heart 2. skeletal…
A: Glucose uptake in the diffrent cells and organs is done by GLUT. GLUT causes facilitated transport…
Q: Explain the H ormonal control of Glucose by cortisol, epinephrine, Growth hormone & thyroxine
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Q: Define the following terms: a. hyperosmolar hyperglycemic nonketosis b. insulin resistance c. JNK d.…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: Ketoacidosis is a common feature of insulin-dependent diabetes mellitus, but not insulinindependent…
A: Diabetic ketoacidosis is a condition occurs when body is not able to produce enough insulin to…
Q: What is the relation between fatty acid oxidation and insulin resistance in the muscle?
A: Alterations in muscle fatty acid metabolism have been implicated in mediating the severity of…
Step by step
Solved in 2 steps
- Describe the probable effect in adipocytes of insulin-stimulated uptake of glucose into these cells.Explain what biochemical pathway/metabolic processes are affected in insulin resistance? How does this affect glycogen breakdown and gluconeogenesis.Describe all the sources of amplification in the insulin receptor system.
- Name two proteins that are effectors of the insulin signaling pathway in adipocytes, liver, or muscle cells. Explain how these effector proteins address the conditions that triggered insulin release.Describe one insulin-mediated mechanism that normally increases glucose uptake into skeletal muscle and adipose tissue when blood glucose levels are high (but would not be operational in T1DM patients)List 2 metabolic characteristics of type 1 diabetes and explain how they are linked to insulin deficiency.
- Predict the biochemical and whole body effects of an overdose of insulinDescribe the process that results in the activation of multiple copies of PKBPKB in response to the binding of a single molecule of insulin to its receptor. Explain why insulin can stimulate the activation PKBPKBof but not the activation of PKPK.Describe the role of ion channels in insulin secretion by the β cells of the pancreas.
- Ketoacidosis is a common feature of insulin-dependent diabetes mellitus, but not insulinindependent diabetes mellitus. Explain.Why might oversecretion of insulin actually reduce glucose uptake by nerve cells?This is a question assigned after reading the case study available here https://sciencecases.lib.buffalo.edu/files/statins.pdf HMG CoA reductase is activated by insulin signaling, and inhibited by glucagon signaling. Explain why insulin resistance and type II diabetes often are accompanied by elevated cholesterol levels.
