ACTIVITY NO. 6CAPILLARY FRAGILITY TEST (Rumple Leede Test)1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity.2.1 Platelets2.2 Vitamin C 3. Give 3 examples for each of the following bleeding disorders associated with vascular abnormalities3.1 Connective Tissue Defects3.1.1 Hereditary3.1.2 Acquired3.2 Altered Vessel Wall Structure3.2.1 Hereditary3.2.2 Acquired 4. Give a brief description of the following term related to hemostasis.4.1 Purpura4.2 Ecchymosis4.3 Hematoma 5. Illustrate and label the different steps of Rumple Leede Test. (picture for reference if answers cannot be found please refer to useful websites) Learning Outcome:At the end of the LABORATORY REPORT, the learner is expected to:1. Efficiently perform the process of doing a capillary fragility test.2. Know the clinical importance of performing a capillary fragility test for patients withbleeding disorders.EXPERIMENT NO. 6: CAPILLARY FRAGILITY TESTPrinciple:The capillary fragility test is also known as the Tourniquet test, Rumpel-Leede Test, Hess test.This test evaluates capillary integrity. It is used to aid in the clinical diagnosis of hemorrhagic feversyndromes such as Dengue Fever.Petechiae occur as a result of increased capillary fragility (microvessels easily rupture and a smallamount of bleeding occurs in the skin) or thrombocytopenia (causing spontaneous bleeding in theskin). There are more accurate tests to indicate platelet count and function. Petechiae are small,round, nonraised red spits in the skin.Production of petechiae can be induced in patients who have increased capillary fragility orthrombocytopenia. There are two methods of inducing petechiae. The most common is with positivepressure. A blood pressure cuff is applied to an extremity and inflated above venous pressure. Thesecond way is with negative pressure. A suction cup is applied to an area of skin for a particularperiod of time. Patients with thrombocytopenia, poor platelet function, or purpura will develop morethan 10 petechiae per square inch of skin. The number of petechiae can be graded from few withconfluent (1 to 4).Indications:Assessment of platelet-vessel wall interactions.Reference Range:Negative or 1+.Within a radius of 2.5 cm:Females = 10 or less petechiaeMales = 5 or less petechiaeREFERENCES:Turgeon, M. L. (1993). Clinical hematology: Theory and procedures. Boston: Little, Brown.Pagana, K. D., Pagana, T. J., & Pagana, T. N. (2015). Mosby's diagnostic and laboratorytest reference (12th ed.). St. Louis, Mo.: Mosby.Walters, N. J., Estridge, B. H., & Reynolds, A. P. (1990). Basic medical laboratorytechniques (2nd ed.). Albany, NY: Delmar. Materials:PROCEDURECAPILLARY FRAGILITY TEST (Rumple Leede Test)1. Blood Pressure Apparatus2. StopwatchProcedure:1. Apply Blood Pressure cuff to the upper arm.2. Initiate the BP cuff at a pressure halfway between the systolic and diastolic pressure andleave it for 5 minutes.3. Remove the BP cuff from the arm and examine the forearm, hand and finger for petechia.4. Report as follows:0-10 petechia11-20 petechia21-50 petechia51 and above+1+ 2+3+4

Question

ACTIVITY NO. 6CAPILLARY FRAGILITY TEST (Rumple Leede Test)1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity.2.1 Platelets2.2 Vitamin C 3. Give 3 examples for each of the following bleeding disorders associated with vascular abnormalities3.1 Connective Tissue Defects3.1.1 Hereditary3.1.2 Acquired3.2 Altered Vessel Wall Structure3.2.1 Hereditary3.2.2 Acquired 4. Give a brief description of the following term related to hemostasis.4.1 Purpura4.2 Ecchymosis4.3 Hematoma 5. Illustrate and label the different steps of Rumple Leede Test.   (picture for reference if answers cannot be found please refer to useful websites) Learning Outcome:At the end of the LABORATORY REPORT, the learner is expected to:1. Efficiently perform the process of doing a capillary fragility test.2. Know the clinical importance of performing a capillary fragility test for patients withbleeding disorders.EXPERIMENT NO. 6: CAPILLARY FRAGILITY TESTPrinciple:The capillary fragility test is also known as the Tourniquet test, Rumpel-Leede Test, Hess test.This test evaluates capillary integrity. It is used to aid in the clinical diagnosis of hemorrhagic feversyndromes such as Dengue Fever.Petechiae occur as a result of increased capillary fragility (microvessels easily rupture and a smallamount of bleeding occurs in the skin) or thrombocytopenia (causing spontaneous bleeding in theskin). There are more accurate tests to indicate platelet count and function. Petechiae are small,round, nonraised red spits in the skin.Production of petechiae can be induced in patients who have increased capillary fragility orthrombocytopenia. There are two methods of inducing petechiae. The most common is with positivepressure. A blood pressure cuff is applied to an extremity and inflated above venous pressure. Thesecond way is with negative pressure. A suction cup is applied to an area of skin for a particularperiod of time. Patients with thrombocytopenia, poor platelet function, or purpura will develop morethan 10 petechiae per square inch of skin. The number of petechiae can be graded from few withconfluent (1 to 4).Indications:Assessment of platelet-vessel wall interactions.Reference Range:Negative or 1+.Within a radius of 2.5 cm:Females = 10 or less petechiaeMales = 5 or less petechiaeREFERENCES:Turgeon, M. L. (1993). Clinical hematology: Theory and procedures. Boston: Little, Brown.Pagana, K. D., Pagana, T. J., & Pagana, T. N. (2015). Mosby's diagnostic and laboratorytest reference (12th ed.). St. Louis, Mo.: Mosby.Walters, N. J., Estridge, B. H., & Reynolds, A. P. (1990). Basic medical laboratorytechniques (2nd ed.). Albany, NY: Delmar. Materials:PROCEDURECAPILLARY FRAGILITY TEST (Rumple Leede Test)1. Blood Pressure Apparatus2. StopwatchProcedure:1. Apply Blood Pressure cuff to the upper arm.2. Initiate the BP cuff at a pressure halfway between the systolic and diastolic pressure andleave it for 5 minutes.3. Remove the BP cuff from the arm and examine the forearm, hand and finger for petechia.4. Report as follows:0-10 petechia11-20 petechia21-50 petechia51 and above+1+ 2+3+4

Accepted Answer

The capillary fragility test also known as the Tourniquet test, Rumpel- Leede, etc tests the…

ACTIVITY NO. 6 CAPILLARY FRAGILITY TEST (Rumple Leede Test) 1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity. 2.1 Platelets 2.2 Vitamin C