43. A 28-year-old man has a fasting serum glucose concentration of 140 mg/dl and a glomerular filtration rate of 125 ml/min. The renal transport maximum for glucose in this patient is 300 mg/min. Which of the following best represents the rate of urinary glucose excretion (in mg/min) in this man? OA) 0 OB) 100 OC) 200 OD) 300 E) 400
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- The normal glomerular filtration rate in the following results is: 1) 2 ml/min, 2) 125 ml/min 3) 800 ml/min 4) 1,200 ml/minTable 3. Serum creatinine values at admission and after 12h Admission +12h SCR(mg/dL) 1.55 1.42 Using the “MDRD” (Modification of Diet in Renal Disease) equation for estimating glomerularfiltration, provided below, and the data available in the above table, calculate the patient's (a 34 year old white male) estimated glomerularfiltration rate (eGFR) at admission and 12h after admission.MDRD GFR Equation (mL/min/1.73 m2)= 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American)Based on your calculated values, state whether LF’s function is normal or abnormal?Previous research suggests that patients with asthma have an increased risk for chronic kidneydisease, but the mechanisms underlying this increased risk are poorly understood. Propose one potential mechanism by which asthma might impair kidney function, and discuss how this dysfunction may impair thebody’s ability to respond to respiratory alkalosisA 28-year-old man has a fasting serum glucose concentration of 140 mg/dL and a glomerular filtration rate of 125 ml/min. The renal transport maximum for glucose in this patient is 300 mg/min. Which of the following best represents the rate of urinary glucose excretion (in mg/min) in this man? (A) 0 (B) 100 (C) 200 (D) 300 (E) 400
- 35. The starting point (X) on the graph represents a person who had been drinking water ad libitum. Which of the following lettered arrows indicates the change that will occur 60 minutes after drinking 1 L of distilled water? OA) 1200- Urine osmolality mOsm/Kg H₂O 900- 600- 300- A E B) B -2 2 D C 4 6 Urine flow rate mL/min C) 8 O D) 10 E)1)Which of the following is NOT associated with a normal first-void urine finding? = trace protein positive glucose 0.1 urobilinogen pH of 6.0 2)A BUN of 60 mg/dL and a 3.5 mg/dL is consistent with which of the following? congestive heart failure nephrotic syndrome glomerulonephritis pyelonephritis 3)A sensitive test for the early detection of renal disease in diabetic patients is the ________________ test.= urine creatinine blood urea nitrogen urinary microalbumin urine pH = 4)An increased serum osmolality is associated with a decreased glomerular filtration rate. True False = 5)Select the influences below that will cause an elevated blood urea concentration. increased dietary protein decreased renal function increased protein catabolism pregnancyA 60-year-old woman with history of lung cancer is admitted for weakness and lethargy for 4 weeks. Her serum [Na*] is 120 mEq/L. She weighs 60 kg. Her serum osmolality is 250 mOsm/kg H2O with urine osmolality of 616 mOsm/kg H2O. The diagnosis of SIADH is made. What would be her serum [Na], if she receives 1 L of isotonic saline? A. 122 mEq/L B. 116 mEq/L C. 118 mEq/L D. 120 mEq/L E. 124 mEq/L
- 24. Measurements are made of the renal tubular fluid concentration of various substances along the length of the proximal tubule and plotted as the tubular fluid to plasma concentration ratio (TF/P). As these substances are reabsorbed along with water, the following profiles are obtained. (All substances are freely filtered at the glomerulus, the TF/P = 1 at the glomerulus.) Glucose is represented by which of the following curves? OA) [Tubular fluid] [Plasma] OB) 3.0- 2.0- 1.0- 0 B O C) E 25 50 75 Proximal tubule length (%) OD) 100 OE)You need to evaluate kidney function in a 55-year-old obese man with type 2 diabetes; you ask him to collect his urine over a 24-hour period. He collects 4,320 mL of urine. The clinical laboratory returns the following results from analysis of his urine and plasma samples: Plasma creatinine = 3.0 mg/100 mL Urine creatinine = 40 mg/100 mL Plasma potassium = 5.0 mmol/L Urine potassium = 20 mmol/L What is the net renal tubular secretion rate of potassium in the patient described in question? Group of answer choices .280 mmol/min .140 mmol/min .060 mmol/min .030 mmol/minCalculate net filtration pressure given the following values: glomerular hydrostatic pressure = 50 mm Hg, blood colloid osmotic pressure = 25 mm Hg, capsular hydrostatic pressure = 20 Hg.
- A patient comes to your medical practice with complaints of low urine output (not peeing). You use inulin to calculate the glomerular filtration rate (GFR) using the following information: Plasma level (P – constant over 24 hours): 10 mg/mL inulin. Urine sample (U): 144 mg inulin/mL urine. Urine formation (V): 10 mL/min. Using the fromula GFR=V ✕ U/P, you calculate a GFR of ... A) 144mL/min.. B) 14400 mL/min. C) 144 min./mL. D) 144 g mannitol/min.4) Measurements in a nephron reveal a glomerular hydrostatic pressure of 69 mm Hg, and a fluid pressure in the Bowman's capsule of 16 mm Hg. Assuming that the plasma colloid osmotic pressure is 33 mm Hg, and that essentially no plasma proteins are filtered by the glomerulus, what is the net glomerular filtration pressure in this case?50. A healthy 54-year-old man who is participating in a study on renal function has been following a high-sodium diet for the past 2 weeks. Which of the following findings in serum are most likely in this man on day 14 compared with prediet values? Na+ Atrial Natriuretic Peptide Angiotensin II OA) OB) C) OD) OE) OF) G) H) T T - - ‡ ‡ ‡ ‡ - ↑ T ↑ ↑ ↓ ↑ ↓ ↑ ↓ ↑ ↓ ↓ ↑
