10. Following a rattlesnake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later, he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathologic process? A) Anaphylactic reaction ( Dy Delayed hypersensitivity to horse proteins (V Formation of antigen-antibody complexes containing horse proteins and/human immunoglobulins Formation of antigen-antibody complexes containing snake venom proteins and horse antibody Systemic reaction to snake venom Senum Sichness. Type 111 hypersensitiving

10. Following a rattlesnake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later, he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathologic process? A) Anaphylactic reaction ( Dy Delayed hypersensitivity to horse proteins (V Formation of antigen-antibody complexes containing horse proteins and/human immunoglobulins Formation of antigen-antibody complexes containing snake venom proteins and horse antibody Systemic reaction to snake venom Senum Sichness. Type 111 hypersensitiving

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter21: The Lymphatic And Immune System

Section: Chapter Questions

Problem 13RQ: Which of the following leads to the redness of inflammation? increased vascular permeability...

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44. Following a rattlesnake bite, a patient is injected with horse anti-rattlesnake venom, serum. Ten days later he has general weakness, muscular and joint pains. Laboratory studies show Proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum c3 and c4 qare decreased. Which is the most likely pathologic proces (A) Anaphylactic reaction (B) Delayed hypersensititvity to horse proteins (C) Formation of antigen-antibody complexes containing horse proteins and human immunoglobulins (D) Formation of antigen-antibody complexes containing snake venom proteins and horse antibody (E) Systemic reaction to snake venom
(38) Following a rattle snake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathological process? (A) Anaphylactic Reaction (B) Delayed Hypersensitivity to horse protei (C) Formation of antigen-antibody complexes containing horse proteins and human immunoglobulin (D) Formsation of antigen-antibody complexes containing snake venom proteins and a horse antibody (E) Systemic reaction to snake venom
43. A patient who has been bitten by a rattlesnake is given an injection of equine anti-rattlesnake venom. Ten days later, he still feels weak all over, has headaches, aches in his muscles and joints, and has black urine. Studies in the lab reveal proteinuria. Immunoglobulin levels in the serum are within the normal range, while serum C3 and C4 levels are lower. Which of the following pathological processes is more likely? (A) Anaphylactic Reaction (B) Delayed Hypersensitivity to horse protein (C) Formation of antigen-antibody complexes containing horse proteins and human immunoglobulin (D) Formsation of antigen-antibody complexes containing snake venom proteins and a horse antibody (E) Systemic reaction to snake venom
16. The Type A Transferase enzyme, attaches N-acetylgalactosamine (GalNAc) to H-antigen epitopes; the Type B Transferase enzyme instead transfers galactose (Gal) to the H-antigen. Individuals with Type A blood thus have at minimum one copy of the active Type A Transferase, those with Type B have at minimum one copy of the active Type B Transferase, those with Type AB have one active copy of each, those with Type O have neither. Imagine an AB individual who acquires a mutation in their Type B Transferase gene that allows it to be active with either Gal or GalNAc. Make sure to include a brief justification for your answer to each question below. a. What blood type antigens would this individual express? b. If this individual had a child with a normal O partner, what possible blood type antigens could the child express? c. If this individual had a child with a homozygous dominant B partner (BB), what possible blood type antigens could the child express?
36) Autoantibodies associated with thrombosis in systemic lupus erythematosus are() A Anti-Sm antibody B Anti-SSA antibody C Anti-cardiolipin antibody D Anti-dsDNA antibody E Anti-nRNPantibody
2. Plasma cells are which type of lymphocyte? Explain, No more than 3-6 sentences. A). T cells B). B cells
1) Discuss the formation of ABH antigens 2) Enumerate the components of CPDA-1 and discuss their respective functions
20) A 19 -year old man comes to the physician because of a severely itchy, blistering rash on his legs for 2 days. The rash began 1 dayafter he went for a walk in a wooded area and has increased in size since then. Physical exmaintaion shows erythematous plaques with vesicles and bullae over both lower extremities. Which of the following is the most likely caise of the patients condition? (A) Activation of the alternative complement pathway (B) Chemical burn caused by toxic plant resins (C) Deposition of immune complexes in the epidermis (D) Infiltrtion of the skin by lymphocytes and macrophages (E) Local discharge of histamine in response to IgE cross lnking of allergen.
I. Attach to mast cells and are involved in allergic reactions. II. The first antibodies to be produced in response to infection. II. Primarily found in glandular secretions. IV. Found on the surface of B lymphocytes. V. Comprises 75% of antibodies in adult blood. What is the correct order of above definitions? A) IgE, IgM, IgA, IgD, IgG. B) IgD, IgM, IgA, IgE, IgG. C) IgE, IgG, IgA, IgD, IgM. D) IgA, IgM, IgE, IgD, IgG.
1. What are the general (basic) functions of antibodies relative to APS? Please include citation (s).
5. A patient receives a donor kidney to replace diseased kidney tissue. Consider and answer the following: B) list two similarities and two differences between response mechanisms of natural killer cells and cytotoxic T cells to the tissue graft in the absence of immune suppression.
Describe three circumstances that might cause antibodies to developagainst self tissues.