Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Textbook Question
Chapter 8, Problem 3R
Match the following examples of mutagens.
| Column A | Column B |
| ___a. A mutagen that is incorporated into DNA in place of a normal base | 1. Frameshift mutagen |
| ___b. A mutagen that causes the formation of highly reactive ions | 2. Nucleoside analog |
| ___c. A mutagen that alters adenine so that it base-pairs with cytosine | 3. Base-pair mutagen |
| ___d. A mutagen that causes insertions | 4. Ionizing radiation |
| ___e. A mutagen that causes the formation of pyrimidine dimers | 5. Nonionizing radiation |
Expert Solution & Answer
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Students have asked these similar questions
Based on the following wild type DNA sequence, indicate if each of the
mutations should be classified as : insertion, deletion, missense, nonsense,
silent (Use the provided Genetic Code table and remember you have been
given DNA sequence).
Wild Type: AUGAUUCUUAAAAGU
Mutant 1: AUGAUUCUUUAAAGU
Mutant 2: AUGAUUCUUGAAAGU
Mutant 3: AUGAUCCUUAAAAGU
Mutant 4: AUGAUCCUAAAAGU
Mutant 5: AUGAUCCUUAAACAGU
Socond letter
Key:
Ala = Alanine (A)
Arg Arginine (R)
Asn =
UUU
}
UAU Tyr
UGU
UGC Cys
UGA STOP
UGG Trp
UCU
UCC
UUC
Phe
Ser
Asparagine (N)
Asp = Aspartate (D)
Cys Cysteine (C)
Gin = Glutamine (Q)
Glu = Glutamate (E)
Gly = Glycine (G)
His = Histidine (H)
le = Isoleucine (1)
Leucine (L)
Lys Lysine (K)
Met = Methionine (M)
Phe = Phenylalanine (F)
Pro Proline (P)
Ser = Serine (S)
Thr Threonine (T)
Trp Tryptophan (W)
Tyr Tyrosine (Y)
- Valine (V)
UCA
UCG
UAA STOP
UAG STOP
UUA
Leu
UUG S
CCU
CC
CGU
CUU
CUC
His
CGC
Arg
Leu
Pro
CAA Gin
CGA
CCA
CCG
CUA
CUG
CGG
Leu =
AGU
AUU
AUC } lle
AUA
ACU
ACC
ACA
Ser
AAC…
I.
The DNA template, 3'–CGTTACCCGAGCOCGTACGATTAGG–5', was exposed to a mutagen,
resulting in the following three templates.
2.
A.
3'–CGTTACCCGAGCCGTAACGATTAGG-5' nserti on
leuding to frame shift
B. 3-CGTTACCCGATCCGTACGATTAGG–5' Point - Transversin
C.
3'-CGTTACCCGAGCCGTTCGATTAGG–5'
Transition
I. Transcribe and translate each template and write down the primary sequence of the resulting
polypeptide/protein.
Describe how each of the mutations will affect the final protein product from the
corresponding template. N
met -gla - Ser- Ala -cys -Stup-d
Predict whether gene expression (from initiation of transcription to final protein product) would be
faster in a prokaryotic or eukaryotic cell. Explain your answer.
Original DNA Sequence:
TACAC CTTGG CGACGACT...
MRNA Sequence:
Amino Acid Sequence:
Mutated DNA Sequence #5 TACACCTT G G GACGACT... (Highlight the change)
What's the mRNA sequence?
What will be the amino acid sequence?
Will there likely be effects?
What type of mutation is this?
1. Which type of mutation is responsible for new variations of a trait?
2. Which type of mutation does not result in an abnormal amino acid sequence?
3.
Which type of mutation stops the translation of an mRNA molecule?
NO
Chapter 8 Solutions
Microbiology: An Introduction
Ch. 8 - Briefly describe the components of DNA, and...Ch. 8 - DRAW IT Identify and mark each of the following on...Ch. 8 - Match the following examples of mutagens. Column A...Ch. 8 - The following is a code for a strand of DNA. a....Ch. 8 - Prob. 5RCh. 8 - Identify when (before transcription, after...Ch. 8 - Which sequence is the best target for damage by UV...Ch. 8 - You are provided with cultures with the following...Ch. 8 - Why are mutation and recombination important in...Ch. 8 - NAME IT Normally a commensal in the human...
Ch. 8 - Nucleoside analogs and ionizing radiation are used...Ch. 8 - Replication of the E. coli chromosome takes 40 to...Ch. 8 - Pseudomonas has a plasmid containing the mer...Ch. 8 - Match the following terms to the definitions in...Ch. 8 - Match the following terms to the definitions in...Ch. 8 - Feedback inhibition differs from repression...Ch. 8 - Bacteria can acquire antibiotic resistance by all...Ch. 8 - Suppose you inoculate three flasks of minimal...Ch. 8 - Plasmids differ from transposons in that plasmids...Ch. 8 - Mechanism by which the presence of glucose...Ch. 8 - The mechanism by which lactose controls the lac...Ch. 8 - Two offspring cells are most likely to inherit...Ch. 8 - Which of the following is not a method of...Ch. 8 - Ciprofloxacin, erythromycin, and acyclovir are...Ch. 8 - HIV, the virus that causes AIDS, was isolated from...Ch. 8 - Human herpesvirus-8 (HHV-8) is common in parts of...
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- A certain section of the coding (sense) strand of some DNA looks like this: 5'- ATGGGCCACTCATCTTAG-3' It's known that a very small gene is contained in this section. Classify each of the possible mutations of this DNA shown in the table below. I Don't Know mutant DNA 5'- ATG GGCCACAGTTCTTAG-3' 5'- ATG GG CTCATCTTAG - 3' 5'- ATG GGCCACGCATCTTAG-3' Submit type of mutation (check all that apply) ооооо O point O silent O noisy ооооо insertion deletion insertion O deletion Opoint Osilent noisy insertion O deletion ооооо Opoint silent O noisy X S Ⓒ2023 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center Accessibilityarrow_forwardMutations can arise in the absence of a mutagen. please explain your answer true falsearrow_forwardwww D le C 3⁰ A B Indicate True (T) or False (F) for the following statements. Only use the letter (T/F) in the space provided 1. The name of this process is best known as Rho dependent termination 2. The enzyme C called DNA polymerase incorporates ribonucleotides into B called the mRNA False 3. The DNA region A contains inverted palindrome sequences which results in formation of a stem-loops structure 4. During this process, the structure D called terminating hairpin forms and increases the enzyme affinity which terminates transcriptionarrow_forward
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