Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 6, Problem 7TYU
When growth hormone binds to an enzyme-linked receptor, (a) G proteins are amplified into a cascade of molecules (b) the enzyme portion of the receptor becomes dephosphorylated (c) the receptor becomes activated and phosphorylates signaling proteins in the cell (d) an ion channel is opened (e) an immediate signal is sent into the nucleus, and specific genes are activated or inhibited
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When a chemical signal binds to an intracellular receptor ...
a) ... it leads to the activation of G proteins.
b) ... causes the receptor-hormone complex to open or close ion channels.
c) ... the cell reacts faster than when a chemical signal binds to membrane-bound receptors.
d) ... it leads to the formation of mRNA.
e) ... the chemical signal is usually a large, water-soluble molecule.
The transforming growth factory beta (TGF-b) family of hormones / growth factors are dimers and they interact with specific receptors. Which of the following statements about these receptors is correct? a) A receptor complex is formed from a type 1 and a type 2 receptor b) A receptor complex is formed between the ligand and the receptor c) This family interacts with a single serine- threonine kinase receptor d) The major receptor is intracellular e) The receptor is a G-protein receptor
Protein phosphorylation is commonly involved with all of thefollowing except(A) activation of receptor tyrosine kinases.(B) activation of protein kinase molecules.(C) activation of G protein-coupled receptors.(D) regulation of transcription by signaling molecules.
Chapter 6 Solutions
Biology (MindTap Course List)
Ch. 6.1 - Describe the four main processes essential for...Ch. 6.1 - What is the sequence of events that takes place in...Ch. 6.1 - Prob. 2CCh. 6.2 - Compare three types of signaling molecules:...Ch. 6.2 - Prob. 1CCh. 6.2 - Prob. 2CCh. 6.2 - Prob. 3CCh. 6.3 - Identify mechanisms that make reception a highly...Ch. 6.3 - Prob. 4LOCh. 6.3 - Prob. 1C
Ch. 6.3 - Prob. 2CCh. 6.3 - Prob. 3CCh. 6.3 - Prob. 4CCh. 6.4 - Prob. 5LOCh. 6.4 - Trace the sequence of events in signal...Ch. 6.4 - How is an extracellular signal converted to an...Ch. 6.4 - Prob. 2CCh. 6.4 - Prob. 3CCh. 6.5 - Prob. 7LOCh. 6.5 - Prob. 8LOCh. 6.5 - Prob. 1CCh. 6.5 - Prob. 2CCh. 6.5 - Prob. 3CCh. 6.6 - Cite evidence supporting a long evolutionary...Ch. 6.6 - Prob. 1CCh. 6 - During signal transduction (a) the cell converts...Ch. 6 - When a signaling molecule binds with a receptor,...Ch. 6 - G proteinlinked receptors (a) inactivate G...Ch. 6 - Prob. 4TYUCh. 6 - Prob. 5TYUCh. 6 - Calcium ions (a) can act as second messengers (b)...Ch. 6 - When growth hormone binds to an enzyme-linked...Ch. 6 - Scaffold proteins (a) release kinases and...Ch. 6 - Prob. 9TYUCh. 6 - Prob. 10TYUCh. 6 - More than 500 genes have been identified in the...Ch. 6 - Prob. 12TYUCh. 6 - Prob. 13TYUCh. 6 - EVOLUTION LINK Cell signaling in plant and animal...Ch. 6 - EVOLUTION LINK Some of the same G proteinlinked...Ch. 6 - Prob. 16TYU
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following statements is true? Question 2 options: a) All cells will respond to the hormonal signal because hormones are broadcast throughout the body. b) The regulation of inflammatory responses at the site of an infection is an example of paracrine signaling. c) Paracrine signaling involves the secretion of stimuli into the bloodstream for distribution throughout the organism. d) The axons of neurons typically signal target cells using membrane-bound signaling molecules that act on receptors in the target cells.arrow_forwardWhich signaling molecule or molecules bind to a G-protein coupled receptor? (note: there may or may not be more then one answer) a) cortisol b) insulin c) glucagon d) calcium e) cyclic AMP f) epinephrinearrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forward
- It is important for the cell to be able to terminate responses, and diminish responsiveness to prevent overstimulation. Cells have different mechanisms for this. One such mechanism is receptor down regulation. a.) Down regulation describes a decrease in the availability of hormones or neurotransmitters that bind to receptors on the surface of target cells, making the cells less likely to be stimulated. b.) Down regulation describes glycosylation of receptor proteins receptors on the surface of target cells in order to decrease the selectivity of ligand binding, making the cells less sensitive to a hormone or neurotransmitter. c.) Down regulation describes a decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or neurotransmitter.arrow_forwardDifferential effects of epinephrine and norepinephrine among cell types and across cell types is dependent on: (Select all that apply) a.) Capillary density b.) Nuclear receptors c.) Type of G-protein expressed d.) Receptor subtype expressionarrow_forwardFat-soluble signaling molecules cross the cell membrane; but they affect only the target cells because: A) Only in target cells is the signaling molecule capable of initiating the phosphorylation chain that activates ion channels. B) only target cells have enzymes that break down the signaling molecule C) intracellular receptors are present only on target cells D) only targets have the appropriate DNA segmentsarrow_forward
- During signal transduction (a) the cell converts an extracellular signal into an intracellular signal that leads to a change in some cell process (b) a signaling molecule directly activates or represses several genes (c) each enzymecatalyzes production of one molecule of product (d) enzymes in the signal cascade remain active until the last component of the pathway alters a cellular process (e) the signal is terminated by cyclic AMParrow_forwardOne such laboratory study investigated the binding of a hormone to three different receptor proteins in the cell membrane. The data collected are shown in the table below: 1) Provide a brief explanation as to why ligand binding to proteins must be a reversible process. 2) Calculate the dissociation constant (Kd) for the hormone binding to each of the three proteins. 3) Which of the proteins demonstrate the tightest/strongest binding of the hormone? Which demonstrates the least tight binding of the hormone? What is the basis for your answer?arrow_forwardWhich receptor undergoes clustering and autophosphorylation in response to activation by a signal? Group of answer choices: a)Ligand-gated ion channels b)Receptor Tyrosine Kinases (RTKs) c)G-Protein Coupled Receptors (GPCRs) d)Nuclear Receptorsarrow_forward
- Cellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'? A) a protein gets tagged with an ubiqutin group and gets degraded B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins C) allosteric regulation causes an active site to be hidden D) All of the other answers are correct E) The ligand is prevented from reaching the binding sitearrow_forwardNerve growth factor binds to which type of receptor? a.) Receptor tyrosine phosphatases b.) Receptor Serine/Threonine Kinase c.) Receptor guanylyl cyclase d.) Receptor tyrosine kinasearrow_forwardWhen activated extracellularly, G protein-coupled receptors (GPCRs) initiate which of the following? (select all that apply) a G protein signaling mechanism inside the cell. b) A G protein signaling mechanism outside the cell. c) Transporters to uptake degraded neurotransmitters for recycling. d) The release of neurotransmitter molecules into the postsynaptic cell.arrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license