Life: The Science of Biology
Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 47.1, Problem 1R
Summary Introduction

To review:

The reason due to which isotropic (I) () band and H zone get smaller, while no change in anisotropic (A) band is observed during the contraction of the skeletal muscle

Introduction:

The basic unit of every organ is cell; however, the specific cells themselves are composed of some simple units, like muscle cells are composed of the myofibrils. The myofibrils contain actin (thin) and myosin (thick) bundles, which are organized in a well-ordered fashion. The myofibril, in turn, is composed of the sarcomeres which are repeated in an order.

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since sarcomeres within skeletal muscles are rigidly aligned with each other what do you think excessive stretch or compression (remember the basic structure of the sarcomere with overlapping thin and thick filaments and the length-tension relationship) will do to the force generation of a muscle contraction?
Why does muscle fatigue occur? since sarcomeres within skeletal muscles are rigidly aligned with each other what do you think excessive stretch or compression (remember the basic structure of the sarcomere with overlapping thin and thick filaments and the length-tension relationship) will do to the force generation of a muscle contraction?
A typical relaxed sarcomere is about 2.3 um in length and contracts to about 2 um in length. Within the sarcomere, the thin filaments are about 1 um long and the thick filaments are about 1.5 um long. (a) Describe the overlap of thick and thin filaments in the relaxed and con- tracted sarcomere. (b) An individual "step" by a myosin head in one cycle pulls the thin fila- ment about 15 nm. How many steps must each actin fiber make in one contraction?
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