Biology
Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 39.2, Problem 1TC
Summary Introduction

To determine:

The method how poison acts to disrupt the nerve function.

Introduction:

In an experiment, neurons are bathed in a solution containing nerve poison. The presynaptic neuron gets stimulated and produces an action potential, but it does not result in post synaptic potential in the postsynaptic neuron. When an individual adds neurotransmitter to the synapse, then also the postsynaptic neurons do not produce post synaptic potential.

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An undisclosed drug (Drug A) is a drug that can block voltage-gated K+ channels when being introduced into the bloodstream. Explain the effects of Drug A on the action potentials produced by a neuron. If Drug A could be applied selectively to a presynaptic neuron that releases an excitatory neurotransmitter, analyse how would it alter the synaptic effect of the neurotransmitter on the presynaptic cell. Remark: The word count limit (250 words only), no less than 100 words
Imagine an experiment in which the neurons pictured here are bathed in a solution containing a nerve poison. The presynaptic neuron is stimulated and produces an action potential, but this does not result in a PSP in the postsynaptic neuron. When the experimenter adds some neurotransmitter to the synapse, the postsynaptic neuron still produces no PSP. How does the poison act to disrupt nerve function?
You generate action potentials in a neuron bathed in solution in a petri dish by applying a threshold-level depolarizing stimulus near its axon hillock. If the solution surrounding the neuron contained 5mM K+, 150 mM Na+, and 0 mM Ca2+ which of the following would you expect? The neuron would not be able to propagate action potentials down the entire length of the axon The neuron would not release neurotransmitter from the axon terminal The neurons action potentials would have an unusually long duration The neuron would have a resting membrane potential of zero
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