Microbiology: A Laboratory Manual (11th Edition)
Microbiology: A Laboratory Manual (11th Edition)
11th Edition
ISBN: 9780134098630
Author: James G. Cappuccino, Chad T. Welsh
Publisher: PEARSON
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Chapter 16, Problem 69E.1RQ
Summary Introduction

To differentiate: Agglutination and precipitin reaction.

Introduction: The two types of primary immunological complex that are formed between the antigen and the antibody can be observed through agglutination and precipitin reactions. A group of homologous proteins is known as antibodies. The antibody and the antigen-binding are highly dependent on specificity.

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Agglutination reaction uses specific antibodies known as agglutinins. These agglutinins are formed in response to particulate antigens. These antigens combine with homologous antibody and form a three-dimensional mosaic complex. These reactions can be viewed with and without a microscope.

In precipitin formation, specific antibodies known as precipitins are involved. A visible precipitate is formed due to the combination of soluble antigen and precipitins.

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