Concept explainers
Introduction:
A mutation refers to the permanent alteration of the DNA (deoxyribonucleic acid) sequence in an organism. The mutations can occur due to the insertion, deletion, or change in the base-pair of the DNA sequence.
Answer to Problem 1TYK
Correct answer:
The change in the base pair during replication process is referred to as a mutation.
Explanation of Solution
Explanation/Justification for the correct answer:
Option (a) is given as a mutation. An alteration in the base-pair of the sequence during the
Explanation for the incorrect answers:
Option (b) is given as mutations that fall in the protein-coding part of the gene. These mutations are known as missense mutations, which also come under mutations only. So, it is an incorrect option.
Option (c) is given as mutation in the transcribed part of the genome. Even, if the mutation does not fall in the protein-coding part or in the transcribed part of the genome, it would still be called as a mutation. So, it is an incorrect option.
Option (d) is given as single base-pair change is not considered as mutation. A change in a single base-pair has the potential to change the whole DNA sequence. Hence, a single base-pair change is also considered as a mutation. So, it is an incorrect option.
Hence, the options (b), (c), and (d) are incorrect.
A mutation is an alteration in the genome. The change in the base-pair of the DNA sequence is always considered as a mutation, no matter where it is present.
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Chapter 16 Solutions
Biological Science (6th Edition)
- Shown below is diagram of RNA polymerase undergoing the process of transcription: This transcript: O Select one: a. None of these choices is correct. O b. has a sequence complementary to the top strand of the DNA. c. has a sequence identical to the top strand of the DNA. d. has a sequence complementary to the bottom strand of the DNA. e. has a sequence identical to the bottom strand of the DNA. f. It is not possible to determine, because not enough information has been provided. g. More than one of these choices is correct. MacEarrow_forwardThe original DNA base sequence is 5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’. What can you conclude about the mutation? A. It is a frameshift mutation. B. It is a silent mutation. C. It is a deleterious mutation. D. It may result in a single amino acid change in the protein being coded for by this base sequence.arrow_forwardIn general, all mutations can be considered harmful, because most genetic systems are already optimized to work correctly and efficiently. A. True b. False; mutations are considered harmful only if they have a direct effect on the ability of cells to synthesize DNA c. False; some mutations are harmful, and some are considered beneficialarrow_forward
- Certain introns can self-excise from RNA. a. false b. truearrow_forwardHow would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forwardArrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forward
- Nonsense mutations occur when: A.The new codon causes an incorrect amino acid to code for an incorrect protein B.The loss or gain of 1 or 2 nucleotides that affects the coding for a protein. C.An alteration in sequence results in a new codon that causes the code to create an incomplete protein. D.Chromosomes break, causing a loss of DNA E.Genes in chromosome mutate and code for incorrect DNAarrow_forwardWhy might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardGive two DIFFERENT examples of how the following can occur:a. A point mutation in an exon that is silent.b. A point mutation in an exon that is NOT silent.c. A point mutation in an intron that is NOT silent.d. A point mutation in a promoter that is NOT silent.arrow_forward
- Which of the following statements are NOT true? A. Replication is the process of making DNA and takes place in the nucleus of prokaryotic cells. B. Translation produces a polypeptide that may require additional processing to become a functional protein C. Transcription starts at the promoter of eukaryotic cells and scans until reaches the start codon. D. Splicing results in exons being put together and introns being removedarrow_forwarda. The reading frame DNA sequence is b. The mRNA sequence is c. The polypeptide sequence is a.The mutated polypeptide sequence is b.What kind of mutation was produced?arrow_forwardA codon is: a. An alternative name for gene b. Three amino acids that encode a nucleotide c. Three nucleotides that encode an amino acid d. One of three nucleotides that encode and amino acidarrow_forward
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