Concept explainers
To determine: The difficulties faced by geneticists in mapping the human genes by using pedigrees.
Introduction: The pedigree analysis is the basic method in human genetics. It is an important tool to study human inherited diseases. The pedigree analysis is mostly used to examine the mode of the inheritance of different genetic diseases.
To determine: The significance of recombinant DNA technology in mapping the human genes.
Introduction: Recombinant DNA technology significantly changed the gene-mapping method. Positional cloning is a recombinant DNA-based method that is used for mapping and the cloning of genes. In this method, prior information about the gene product or its function is not required.
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Human Heredity: Principles and Issues (MindTap Course List)
- What impact has recombinant DNA technology had on genetics and society?arrow_forwardIs genetic engineering and recombinant DNA technology helpful to society? Why?arrow_forwardA researcher used polymerase chain reaction (PCR) to test four individual nematodes for the presence of a mutation in Gene Y. When amplified, the fragments of DNA containing the mutated gene alleles were 250 base pairs long and the normal (wild type) alleles were 350 base pairs long. To identify the genotypes of the individual nematodes, the researcher used gel electrophoresis to visualize the PCR results. 1.000 bp 500 bp 300 bp 200 bp 100 bp Remember that these nematodes are diploid organisms and as such, inherited two copies of Gene Y. Which of the following statements is a correct analysis of these results a) Nematode As homozygous for this gene and has two copies of the mutated allele. O b) Nematode C is heterozygous for this gene and has one copy of the mutated allele and one copy of the normal (wild type) allele. O) Nematode D is heterozygous for this gene and has one copy of the mutated allele and one copy of the normal (wild type) allele. ) d) Nematode B is homozygous for this…arrow_forward
- If you had the ability to do gene editing with ONE gene for the betterment of human kind, which one would you choose, and why? Assume you could either change an abnormal allele associated with a disease, such as the cystin gene associated with Cystic Fibrosis to its normal wild type, or add a pre-existing human allele to a genome.arrow_forwardWhy do Humans require pedigree analysis instead of breeding experiments to determine how a trait is inherited?arrow_forwardHow could personal DNA testing be beneficial to medicine?arrow_forward
- How to find the human chromosome DNA sequence ? Where I can get exact data ?arrow_forwardImagine you've been offered a deal from a genomics company. You can get a free genome sequence – an analysis of all your DNA that includes a report of your ancestry, traits and a medical profile. The medical profile tells you about diseases for which you have a low risk of getting, and also those you have a high risk of getting. Are you interested? Why or why not?arrow_forwardWhat is the human genome project and what were its goals and two big surprises?arrow_forward
- Humans have engaged in genetic manipulation for millennia, producing plant and animal varieties through selective breeding and hybridization that significantly modify genomes of organisms. Why do you think modern genetic engineering, which often entails introducing or modifying only one or a few genes, has met with so much opposition? Should some forms of genetic engineering be of greater concern than others? Explain.arrow_forwardWhat is your opinion on the use of DNA engineering in creating perfect genes of babies?arrow_forwardWe all carry about 20,000 genes in our genome. So far, patents have been issued for more than 6000 of these genes. Do you think that companies or individuals should be able to patent human genes? Why or why not?arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning