Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 15, Problem 2P
Summary Introduction

To examine:  Whether the statement “in the regulation of molecular switches, protein kinases and guanine nucleotide exchange factors (GEFs) always turn proteins on, whereas protein phosphatases and GTPase-activating proteins (GAPs) always turn proteins off” is true or false.

Introduction:

Second messengers are small intracellular signaling molecules which are released in response to extracellular signals known as first messengers. These intracellular signaling molecules are known as molecular switches. After their release, they diffuse and bind to the target, and bring a functional change for their activation (ON) or deactivation (OFF).

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