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Gastroenterology
Two drugs (A, B) are compared for the medical treatment of duodenal ulcer. For this purpose, patients are carefully matched with regard to age, gender, and clinical condition. The treatment results based on 200 matched pairs show that for 89 matched pairs both treatments are effective; for 90 matched pairs both treatments are ineffective; for 5 matched pairs drug A is effective, whereas drug B is ineffective; and for 16 matched pairs drug B is effective, whereas drug A is ineffective.
Perform the test in Problem 10.8, and report a p-value. In the same study, if the focus is on the 100 matched pairs consisting of male patients, then the following results are obtained: for 52 matched pairs both drugs are effective; for 35 matched pairs both drugs are ineffective; for 4 matched pairs drug A is effective, whereas drug B is ineffective; and for 9 matched pairs drug B is effective, whereas drug A is ineffective.
10.8 What test procedure can be used to assess the results?
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