Which specialized gene product is responsible for the fusion of mononucleated skin fibroblasts into multinucleated skeletal muscle cells in humans (a type of positive feedback in gene expression)? the glucocorticoid receptor protein the antennapedia protein the PAX-6 protein the MyoD protein the Ey protein

Which specialized gene product is responsible for the fusion of mononucleated skin fibroblasts into multinucleated skeletal muscle cells in humans (a type of positive feedback in gene expression)? the glucocorticoid receptor protein the antennapedia protein the PAX-6 protein the MyoD protein the Ey protein

Name: Which specialized gene product is responsible for the fusion of mononu
Uploaded: 2024-03-20T06:42:41.000Z
Channel: Bartleby
Description: Which specialized gene product is responsible for the fusion of mononucleated skin fibroblasts into multinucleated skeletal muscle cells in humans (a type of positive feedback in gene expression)?the glucocorticoid receptor proteinthe antennapedia pr

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 13QP: Suppose that in the formation of phenylalanine hydroxylase mRNA, the exons of the pre-mRNA fail to...

See similar textbooks

Similar questions

Mutations to SRP72 (the RNA component of the signal recognition particle) are known to cause some forms of familial bone marrow failure. Which of the following protein(s) is/are potentially affected by such deleterious mutations? Choose all that apply Epidermal growth factor receptor (EGFR) Cytochrome c Insulin (a secreted protein) uS7 (a small ribosamal subunit protein from all dornains of life) DO00
Marfan syndrome is due to a mutation in a gene that encodes aprotein called fibrillin-1. It is inherited as a dominant trait. Thefibrillin-1 protein is the main constituent of extracellular microfibrils.These microfibrils can exist as individual fibers or associatewith a protein called elastin to form elastic fibers. People with thedisorder tend to be unusually tall with long limbs, and they mayhave defects in their heart valves and aorta. Let’s suppose aphenotypically unaffected woman has a child with a man whohas Marfan syndrome.A. What is the probability this child will have the disease?B. If this couple has three children, what is the probability thatnone of them will have Marfan syndrome?
A human gene called theCFTR gene (for cystic fibrosis transmembrane regulator) encodes aprotein that functions in the transport of chloride ions across the cellmembrane. Most people have two copies of a functional CFTR geneand do not have cystic fibrosis. However, a mutant version of the CFTRgene is found in some people. If a person has two mutant copies ofthe gene, he or she develops the disease known as cystic fibrosis. Arethe following descriptions of this disease related to genetics at themolecular, cellular, organism, or population level?A. People with cystic fibrosis have lung problems due to a buildupof thick mucus in their lungs.B. The mutant CFTR gene encodes a defective chloride transporter.C. A defect in the chloride transporter causes a salt imbalance inlung cells.D. Scientists have wondered why the mutant CFTR gene is relativelycommon. In fact, it is the most common mutant gene that causesa severe disease in persons of Northern European descent. Onepossible explanation why…
Protein-X has a calcium (Ca²+)-binding regulatory subunit. Upon calcium (Ca²+) binding the protein changes its own conformation resulting in the conformation change of protein-Y. As a result of this calcium (Ca²+)-dependent protein-X mediated conformational change protein-Y exposes the myosin II head binding sites on the skeletal muscle actin filaments. Identify the protein-X and protein-Y from the following choices. O Protein-X: Troponin; Protein-Y: Tropomysosin O Protein-X: Tropomodulin; CapZ O Protein-X: Nebulin; Protein-Y: Titin Protein-X: Tropomysosin; Protein-Y: Tropomodulin
Consider the example that actin mRNA localization is important for fibroblast migration. What would you predict to be the consequence of deleting the zip code sequence element of the actin mRNA?
Nucleation of straight, single line microfilaments is mediated by which of the following? Rho GTPase and Formin Rho GTPase and Arp 2/3 Cdc42 GTPase and Arp2/3 OCdc42 GTPase and Formin 14 < Previous
Long non-coding RNAs (lncRNA) can act as a scaffold to form protein/RNA complexes that regulate gene expression? True False Wnt is a regulatory factor that regulate myogenic stem cell proliferation? True False
It is not an easy matter to assign particular func-tions to specific components of the basal lamina, sincethe overall structure is a complicated composite materialwith both mechanical and signaling properties. Nidogen,for example, cross-links two central components of thebasal lamina by binding to the laminin γ-1 chain and totype IV collagen. Given such a key role, it was surprisingthat mice with a homozygous knockout of the gene fornidogen-1 were entirely healthy, with no abnormal phe-notype. Similarly, mice homozygous for a knockout of thegene for nidogen-2 also appeared completely normal. Bycontrast, mice that were homozygous for a defined muta-tion in the gene for laminin γ-1, which eliminated just thebinding site for nidogen, died at birth with severe defectsin lung and kidney formation. The mutant portion of thelaminin γ-1 chain is thought to have no other functionthan to bind nidogen, and does not affect laminin struc-ture or its ability to assemble into the basal lamina.…
Given the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks please put in the correct letter for the questions What region would provide cell type-specific expression of genes? region What site would significantly increase gene expression rates? = region What region or regions of this gene’s coding sequence are expressed as amino acids = region
The oscillatory clock that drives somite forma-tion in vertebrates involves three essential componentsHer7 (an unstable repressor of its own synthesis), Delta (atransmembrane signaling molecule), and Notch (a trans-membrane receptor for Delta). Notch is bound by Delta onneighboring cells, activating the Notch signaling pathway,which then activates Her7 transcription. Normally, thissystem works flawlessly to create sharply defined somites(Figure Q21–2A). In the absence of Delta, however, onlythe first five somites form normally, and the rest are poorlydefined (Figure Q21–2B). If a pulse of Delta is suppliedlater, somite formation returns to normal in the regionswhere Delta was present (Figure Q21–2C). A diagram ofthe connections between the components of the clockand how they interact in adjacent cells is shown in FigureQ21–2D. In the absence of Delta, why do the cells becomeunsynchronized? What is it about the presence of Deltathat keeps adjacent cells oscillating in synchrony?
1117 increase in the number of passive glucose transporter on the muscle cell surface thus increases the uptake of glucose into the cell and decreases blood glucose level. Indicate whether the following conditions/practice will likely lead to diabetes (mark Yes or No). [Select] a mutation in a V-SNARE in islet cells that blocks all secretion Q Search ******* 40 ****** 99+ app.honorlock.com is C
The Wnt planar polarity signaling pathway nor-mally ensures that each wing cell in Drosophila has a sin-gle hair. Overexpression of the Frizzled gene from a heat-shock promoter (hs-Fz) causes multiple hairs to grow frommany cells (Figure Q15–5A). This phenotype is suppressedif hs-Fz is combined with a heterozygous deletion (DshΔ)of the Dishevelled gene (Figure Q15–5B). Do these resultsallow you to order the action of Frizzled and Dishevelledin the signaling pathway? If so, what is the order? Explainyour reasoning