Which of the following statements concerning p53 is NOT correct? O a. O b. O C. p53-dependent transcription of target genes leads to cell cycle arrest or cell death (apoptosis). Loss of p53 function results in loss of checkpoint controls. Loss of p53 function creates an environment that is permissive for genome instability--that is, more damaged cells with chromosome aberrations and mutations survive and propagate. O d. p53 is a tumor suppressor protein which is largely responsible for protecting cells from cancer- causing DNA-damaging agents.

Which of the following statements concerning p53 is NOT correct? O a. O b. O C. p53-dependent transcription of target genes leads to cell cycle arrest or cell death (apoptosis). Loss of p53 function results in loss of checkpoint controls. Loss of p53 function creates an environment that is permissive for genome instability--that is, more damaged cells with chromosome aberrations and mutations survive and propagate. O d. p53 is a tumor suppressor protein which is largely responsible for protecting cells from cancer- causing DNA-damaging agents.

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Description: Which of the following statementsconcerning p53 is NOT correct?O a. p53-dependent transcription of target genes leadsto cell cycle arrest or cell death (apoptosis).O b.O C.Loss of p53 function results in loss of checkpointcontrols.Loss of p53 functi

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter10: Control Of Gene Expression

Section: Chapter Questions

Problem 15SA: Match the terms with the most suitable description. ___ methylation a. makes a man out of you ___...

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Biologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.
Match the terms with the most suitable description. ___ methylation a. makes a man out of you ___ SRY gene b. binding site for repressor ___ operator c. cells become specialized ___ Barr body d. can be epigenetic ___ differentiation e. inactivated X chromosome
All yhe cell in the human body has the same genome but have differences in their structure and function performed . what could be the reason ?
// Which CDK and cyclin does p53 ultimately target in DNA damaged conditions? O CDK1/cyclin E O CDK2/cyclin E CDK1/cyclin B CDK2/cyclin B
Match the following terms with the correct description Go phase A. During this phase, the cell divides into two identical cells. G, phase B. During this phase, the cell grows In size and synthesizes MRNA Gz phase C. This phase directly precedes mitosis. s phase D. This phase can be percelved as a moment in time in which the cell is nelther dividing nor preparing to divide. M phase E. DNA Is replicated during this phase.
When p53 is activated, a cell cannot progress: A. throught M-phase B. from G2 into M phase C. From G1 into S phase D. Throught S-phase E. from s-pahse into G2
Sometimes a cells "deal with" damaged DNA by just killing off the cell. This special cellular suicide is called apoptosis. Usually, the cell cycle has checkpoints that prevent damaged/mutated cells from proceeding to the next phase, though. When these checkpoints don't work, apoptosis can be used. If apoptosis did NOT occur, how might the damaged DNA impact the rest of the cell cycle? A. it may not complete the cell cycle correctly B. new cells containing damaged DNA may be made C. the cell may enter G0 D. all of the above are options E. A and B, but not C F. B and C, but not A
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of my celle chose are wels smaller than normal. According to Model 1, what part(e) of the cell cycle is (ere) ou likely being affected? Some cancerus me 7. In Model 1, if the length of the arrow represents time, then for those cancerous cells, what hap pens to the time that is necessary for the cell cycle? What implication might this have for doctors who are treating cancer patients? Why? Living things must grow and develop. At times they suffer injuries or damage, or cells simply wear out. New cells must be formed for the organism to survive. What process must occur to make a new, properly- functioning cell? Model 1 - Mitosis as Part of the Cell Cycle Prophase Metaphase Anaphase Mitosis How do living things grow and repair themselves! Replicated chromosome (2 sister chromatids) 0000 * Centriole Spindle fibers Nuclear membrane Telophase 1. Refer to Model 1. List the four phases in the mitosis process. 2. Where is mitosis in the cell cycle? Before 3. What three phases of the cell cycle…
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