Using the Koch's Postulates, support the finding that Mycobacterium tuberculosis is the causative agent of tuberculosis. Specifically, you have to provide brief narratives/pictures/proofs and sources that support the postulate listed below: The organism must be isolated from the newly infected animals and cultured again in the laboratory, after which it should be seen to be the same as the original organism.

Using the Koch's Postulates, support the finding that Mycobacterium tuberculosis is the causative agent of tuberculosis. Specifically, you have to provide brief narratives/pictures/proofs and sources that support the postulate listed below: The organism must be isolated from the newly infected animals and cultured again in the laboratory, after which it should be seen to be the same as the original organism.

Microbiology for Surgical Technologists (MindTap Course List)

2nd Edition

ISBN:9781111306663

Author:Margaret Rodriguez, Paul Price

Publisher:Margaret Rodriguez, Paul Price

Chapter9: Microbial Disease Transmission

Section: Chapter Questions

Problem 4UTM

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As an illustration, a patient undergoing a laparoscopic-assisted vaginal hysterectomy (LAVH) procedure under general anesthesia might be happier not to know the numbers of portals of entry for potential transmission of pathogenic microbes to which she will be subjected. The anesthesia provider would be accessing the patients airway and vascular system by an IV line. Which portals of entry will the surgeon be accessing?
In 2005, J. Robin Warren and Barry J. Marshall shared theNobel Prize in Medicine for discovering the bacteriumHelicobacter pylori and for establishing experimental proofthat it plays a major role in gastritis and peptic ulcer disease.The story began when Warren, a pathologist, noticed thatbacilli were associated with the tissues taken from patientssuffering from ulcers. Look up the history of this case and describeWarren’s first hypothesis. What sorts of evidence did ittake to create a credible theory based on it?
The general public takes for granted the link between an infectious agent and a given infection Discuss the requirements established by Koch, the nineteenth-century German scientist, before ascertaining, for instance, that Helicobacter pylori bacterium is the cause of the gastric ulcer. Why is it so essential to meet these conditions?
1.Explain three reasons why Koch’s postulates are difficult to carry out today and why it can not be a process that is exclusisely used for every disease. 2.Explain the pathogenic mechanism of Tuberculosis. Be sure to include the importance of phagocytes, mycolic acid and the tubercle.
Explain the steps involved in using Koch's postulate to establish the link between a suspected microorganism and disease.
The following are the limitations of Koch's postulates EXCEPT: A. some pathogens cannot grow on artificial media and therefore cannot be identified as the causative agent of the disease B. some diseases involve multiple pathogens which produce similar symptoms making it difficult to pinpoint the causative agent C. some diseases are host-specific and re-inoculation may pose ethical concerns D. some microorganisms are present in the body fluids of the infected animal which make them difficult to be cultured
Explain how and why antibacterial treatment for tuberculosis differsfrom that for other bacterial pathogens.
A. What is Pasteur’s “Germ Theory of Disease?. How did he discover this principle? B. What major obstacle did he have to overcome (A philosophical concept) to establish the validity of the theory.
In light of the current pandemic, give one strategy that scientists have developed to discover new antimicrobial agents. explain the strategy, the benefits and the current development of this strategy.
List Koch’s postulates, and discuss when they might not be appropriate in establishing causation.
Clostridium difficile infection is the leading causeof hospital-associated gastrointestinal illness. It is typicallytreated with a course of antibiotics, but the infection recursin about 20% of cases. C. difficile infections are difficult toeradicate because the bacteria exist in two forms: a repli-cating, toxin-producing form and a spore form that is resis-tant to antibiotics. Fecal microbiota transplantation—thetransfer of normal gut microbiota from a healthy individ-ual—can resolve >90% of recurrent infections, a much bet-ter cure rate than further antibiotic treatment alone. Whydo you suppose microbiota transplantation is so effective?