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- Mendel studied a tall variety of pea plants with stemsthat are 20 cm long and a dwarf variety with stems thatare only 12 cm long.a. Under blending theory, how long would you expectthe stems of first and second hybrids to be?b. Under Mendelian rules and assuming stem lengthis controlled by a single gene, what would you expectto observe in the second-generation hybrids if all thefirst-generation hybrids were tall?In Figure 1-6, the students have 1 of 15 different heights,plus there are two height classes (4′11″ and 5′ 0″) forwhich there are no observed students. That is a total of17 height classes. If a single Mendelian gene can account for only two classes of a trait (such as purple orwhite flowers), how many Mendelian genes would beminimally required to explain the observation of 17height classes?In Mendel’s 1866 publication as shown in Figure 1-4,he reports 705 purple-flowered (violet) offspring and224 white-flowered offspring. The ratio he obtained is3.15:1 for purple: white. How do you think he explainedthe fact that the ratio is not exactly 3:1?
- The text outlines some of the problems Frederick William I encountered in his attempt to breed tall Potsdam Guards. a. Why were the results he obtained so different from those obtained by Mendel with short and tall pea plants? b. Why were most of the children shorter than their tall parents?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?For all seven characters described in the data of Mendel allowed the F2 plants to self-fertilize. He found that whenF2 plants with recessive traits were crossed to each other, theyalways bred true. However, when F2 plants with dominant traitswere crossed, some bred true but others did not. A summary ofMendel’s results is shown to the right When considering the data in this table, keep in mind that theydescribe the characteristics of the F2 generation parents that haddisplayed a dominant phenotype. These data were deduced byanalyzing the outcome of the F3 generation. Based on Mendel’slaws, explain why the ratios were approximately 1:2In this program, you are provided with phenotype pair counts of F2 offspring at two research institutes. The key different between this work and previous work is that now we consider two genes instead of one. The phenotype pairs are the (shape, color) of peas from a pea plant. It turns out that there are two separate genes that code for these phenotypes. We shall call them Shape and Color. Gregor Mendel originally recorded these experiments in green peas. Using the notation: R = Round (dominant) allele at Shape gene; r = Wrinkled (recessive) allele at Shape gene; Y = Yellow (dominant) allele at Color gene; y = Green (recessive) allele at Color gene; then the shape and color of any pea can be determined by studying the genotypes at each gene. It turns out that, when one mates a plant that is homozygous for the dominant alleles (RRYY) with a plant that is homozygous for the recessive alleles (rryy), the F1 generation are heterozygous at both genes, as with a single gene disorder.…
- 1) Identify the most important advantage that Mendel's pea plants had for studying the inheritance of traits 2) Using no more than one sentence, please explain why this advantage or characteristic was critical for the success of Mendel's experimentsA corn geneticist wants to obtain a corn plant that hasthe three dominant phenotypes: anthocyanin (A), longtassels (L), and dwarf plant (D). In her collection ofpure lines, the only lines that bear these alleles are AALL dd and aa ll DD. She also has the fully recessive lineaa ll dd. She decides to intercross the first two and testcross the resulting hybrid to obtain in the progeny aplant of the desired phenotype (which would have to beAa Ll Dd in this case). She knows that the three genesare linked in the order written, that the distance between the A/a and the L/l loci is 16 m.u., and that thedistance between the L/l and the D/d loci is 24 m.u.a. Draw a diagram of the chromosomes of the parents,the hybrid, and the tester.b. Draw a diagram of the crossover(s) necessary toproduce the desired genotype.c. What percentage of the testcross progeny will be ofthe phenotype that she needs?d. What assumptions did you make (if any)?Mendel obtained his initial pea plant varieties from local breeders who were developing new varieties that might be useful or interesting. To generate these new varieties, breeders formed hybrids between existing varieties of different phenotypic characteristics by cross-pollination, using techniques they doubtless taught to Mendel. After producing a hybrid, they allowed several generations of self-pollination, as happens naturally if the flowers are not disturbed. i. How many generations would it take for a breeder to have produced new pure-breeding varieties using this approach? ii. What is the probability that an individual in each of these generations (F2, F3, and F10) would be homozygous for one or the other allele of this gene? [Broad hint: if they’re not heterozygous, they’re homozygous!] please answer and explain properly