relation between Polymorphism & amorphism in physicochemical properties relation between pKa of drug & gastrointestinal pH in physicochemical properties
Q: 2.1.2 Structural diversity of ß-sitosterol and its analogues 2.1.3 Types of molecular interactions…
A: Introduction: Plant sterols, such as beta-sitosterol, are a type of chemical. It's a lipid that's…
Q: There are two competing processes for the manufacture of lactic acid, chemical and biochemical…
A: Lactic acid is an organic compound, its Chemical name is 2-hydroxypropanoic acid and belongs to…
Q: Suggest a transition state analog for proline racemase that differs from those discussed in the…
A: Since enzymes eventually work to stabilise the reaction's transition state, it's no surprise that we…
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A: The amphipathic character of bile salts allows for their interaction with the lipid bilayer of cell,…
Q: From a medicinal chemistry (and a pharmacologist) perspective, functional groups provide specific…
A: Pharmacokinetics defines the fate of a drug in the body. It includes absorption, distribution,…
Q: a molecule that lowers cholesterol levels in humans interacts with the enzyme HMA-COG reductase. how…
A: Statins are the molecules responsible for lowering the levels of total bad cholesterol,…
Q: Połymer formation from a pool of available monomers with a range of chemical functionalities…
A: Introduction:- The quetion is about the biomolecules that are polymers that made up of small units…
Q: Peptide YY (PYY) is a 36-amino acid peptide that is so named because it contains twobiochemically…
A: Peptide YY (PYY) is 36-amino-acid peptide and contains two biochemically relevant tyrosine residues
Q: pH Sensitivity of the Glu-GABA Antiporter 1 G 300 GadC AdC 250 SIA 2onendmoM enoto bbl 200 ale biu A…
A: E. coli has following mechanism in normal cell to survive in acidic pH: Conversion of Amino caid…
Q: Discuss the biochemical interactions that cause identical twins to not be identical. Please ensure…
A: Gene interaction is a wide term phenomenon to explain the collective role of multiple genes in…
Q: Compute for the AST (Aspartate Aminotransferase activity) of 0.10 mL serum sample mixed with 1mL of…
A: Step 1 AST activity: AST or Aspartate Aminotransferase activity is the measurement of AST in blood.…
Q: Which of the following statements regarding Ramachandran plots is false? Bond angle conformations of…
A: The Ramachandran plot is a fundamental tool in the analysis of protein structures.
Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…
A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…
Q: discuss the absorption spectra of the 3 amino acids Arginine, Leucine and Proline.
A: Amino acids are biological molecules that contain an alpha-carboxylic acid and an-amino group. The…
Q: Kappa- and Iota- carrageenans contain 3,6-anhydro-a-D-galactopyranosyl residues. True False
A: Carrageenans are a family of hydrocolloids used for thickening, stabilizing, and gelling solutions.…
Q: Please explain why RNA but not DNA will be hydrolyzed by an increase in pH based upon the…
A: DNA or deoxyribonucleic acid is the genetic material of most organisms. This is made up of two…
Q: under certain conditions alpha helical bundles can form and can facilitate protein insertion into…
A: Integral membrane proteins fold into their active conformations in a complex milieu dictated by the…
Q: The amino acid that is often used as a tag (in a run of 6-8 of this amino acid in a row) for protein…
A: Living cells have a complex system for protein synthesis. Ribosomes synthesize amino acid chains.…
Q: ubiquitin attaches to proteins via many biochemical reactions, please explain how this attachment…
A: Ubiquitin is a highly conserved 76-residue monomeric protein found in eukaryotes. It is found in…
Q: There are 4 classes of biochemical families (Carbohydrates, Proteins, Lipids, and Nucleic Acids).…
A: Carbohydrates are classified as monosaccharides, oligosaccharides, and polysaccharides. The…
Q: What's the simple rule to predict ligand binding sites for Rossmann Fold
A: Proteins are polypeptides consisting of unbranched polymers constructed from 22 standard α-amino…
Q: SPR is one of many techniques to examine binding affinities of biomolecules. Choose another…
A: SPR is a signal peptide that can arise from the exit site of the ribosome and forms the ribosome SRP…
Q: Absorbance spectrum of Ninhydrin curve 1,6 1,4 1,2 0,8 0,6 0,4 0,2 100 200 300 400 500 600 700 800…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: Y,G,I,F,L,Y what is the biochemical propities of this residues.
A: Amino acids are organic molecules which are extremely essential components of all organisms. These…
Q: Write the biochemical structures of bicarbonate buffer Phosphate buffer and protein buffer.…
A: Bicarbonate buffer system It is used to balance pH in blood and duodenum along with some other…
Q: Bioactivity and structural novelty of Cephanolide A
A: The first complete asymmetric compilation of Cephanolide A, a hexacyclic C18 dinorditerpenoid…
Q: A patient is suffering from hemoglobinopathies and the principal biochemical defect that leads to…
A: Haemoglobinopathies is a blood disorder.
Q: Discuss the reaction conditions you would need to carry out the PEGylation reaction of this peptide…
A: In order to solve a variety of biopharmaceutical inadequacies, the word "PEGylation" refers to the…
Q: the major biochemical function of B vitamins within the human body is as:
A: Vitamins are a group of substances that are required for normal cell function, development, and…
Q: [References] The peptide aspartame, shown in the sketch drawing window, has several ionizable…
A: Aspartame is a dipeptide which is used as artificial sweetener and is 200 times more sweet than…
Q: using specific examples explain the biochemical significance of saturated and unsaturated fatty…
A: Our body needs energy for the proper functioning of all the organs and to sustain the metabolic…
Q: What is the biochemical rationale for the use of creatine?
A: Creatine Phosphate has higher phosphoryl transfer potential as compared to ATP
Q: Briefly explain how ester hydrolysis experiments helped to provide evidence for the mechanism of…
A: Carboxylic acid and free alcohol are formed by an ester hydrolysis reaction that breaks an ester…
Q: explain why A liposome of 1;1 molar ratio of cholesterol to phospholipids will be the optimum…
A: Liposomes are artificially engineered vesicles for drug transport. There membranes are composed of 2…
Q: . Studies on CAMP actions in cultured cells usually involve adding to the cell culture not CAMP, but…
A: cAMP is a secondary messenger involved in many biological processes. cAMP is derived from ATP and…
Q: . In what ways do the systematic developments of pesticidesand of pharmaceuticals resemble each…
A: Pesticides and pharmaceuticals are molecules that are derived from common organic compounds linked…
Q: Major functional groups present and expected wavenumbers of the peaks: Attach IR spectrum of the…
A: Infrared (IR) spectroscopy is technique which is used to measure the interaction of IR radiation…
Q: Describe in detail with the aid of diagrams the use of chemical shift perturbation mapping to…
A: Before getting into protein-ligand binding site mapping using chemical shift perturbations, lets…
Q: what do you mean by structure activity relationship(SARs) in drug discovery?
A: SAR, structure-activity relationship, helps to synthesize a compound for drug discovery.
Q: Similarly, hypoxanthine (HX) can be used to label purine residues. As in Problem 4, write reactions…
A: It is given that hypoxanthine can be used to label the purine residues. Hypoxanthine always pair…
Q: On Dimyristoyl phosphatidylserine, Palmytoyl-Oleoyl Phosphatidylcholine and Sphingomyelin, What is…
A: Non-covalent interactions play an essential role in biomolecule interactions. The non-covalent…
Q: Is there a difference in the omega-3 fats derived from plant and animal sources? If so, explain the…
A: Omega-3-fatty acid are polyunsaturated fatty acid (PUFA). In omega-3-fatty acid, the double bond is…
Q: Discuss one biologically active peptide. How important is it in biochemical processes?
A: Bioactive peptides are inferred from food proteins and have a significant impact on human health due…
Q: sequences of peptides tha" of trypsin? eptadecapeptide Cortistau
A:
Q: Cone snails are carnivores that inject a powerful set of toxins into their prey, leading to rapid…
A: A rare species of cone snail carnivoures is a powerful venom for their prey. Its powerful venom…
relation between Polymorphism & amorphism in physicochemical properties
relation between pKa of drug & gastrointestinal pH in physicochemical properties
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- Połymer formation from a pool of available monomers with a range of chemical functionalities contributes to biochemical molecular complexity. True FalseExplain the biochemical defect that leads to Lesch-Nyhan syndrome and suggest how the defect might cause the behavioral symptoms characteristic of the disorder.What is the charge on the following peptide at standard biochemical pH? S-Y-D-F-K-I-V-F-L-L +2 -1 0 0 0-2 O +1
- Quantitative Estimation of Amino Acids by Ninhydrin http://vlab.amrita.edu/?sub=3&brch=63&sim=156&cnt=2 can u help me with question 2 of the assignment questions Based on the experimental data provided, estimate the amount of amino acid in the given unknown solution by Ninhydrin method. SI No. Volume of standard amino acid solution (ml) Amount of amino acid (µg) OD at 570nm 1 Blank 0 2 0.2 0.12 3 0.4 0.25 4 0.6 0.45 5 0.8 0.55 6 1.0 100 0.68 7 Unknown (0.5ml) 0.41whether a protein can to work in the same way in two different types of cells and if it possible that the same protein might function in different biochemical pathways in eye cells and muscle cells even if the protein's basic mechanism always remains the same. MAExplain the Rf value obtained on the basis of the structure of amino acids use. Explain in 1-3 sentence only.
- Difference between inositol triphosphate and cyclic Ampwhat is lactose intolerance ? describe the molecular life cycle for this disease. also describe how it occurs in a molecular level detailed mechanism. what causes this disease and how it develops ? provide detailed biochemical phenomena and life cycle for Lactose Intolerance condition.Maintaining the proper structure of high value biopharmaceutical proteins like monoclonal antibodies throughout downstream processing is critical to process economics. What factors (at least 3) should be considered/controlled to maintain proper 3-dimensional configuration?
- BIOCHEMISTRY Why does a dual layer of Cr/Au (20/100nm) delaminate during a GSTAT electrochemical polymerization of PEDOT:PSS?Instruction for the said activity: Write the structure of each of the following peptide at pH7 and identify how many peptide bond in each number. d. Alanyl-phenylalanine- aspartate- cysteine e. Threonyl- Isoleucyl-methionyl- leucine f. Lysyl-alanine -Phenylalanyl-tyrosyl- serineunder certain conditions alpha helical bundles can form and can facilitate protein insertion into membranes. discuss how they coudl achieve this at a biochemical level?