Reading Comprehension Question. This is a description of one type breast cancer. One in five invasive breast cancers is HER2-positive, making this one of the more common breast cancer subtypes in the United States. HER2-positive cancers are ER- and PR-negative and human epidermal growth factor receptor 2 (HER2)-positive. HER2-positive breast cancer cells carry too many copies of the HER2 gene, which makes HER2- protein receptors, found on breast cells. When they work normally, HER2 receptors control how a healthy breast cell grows, divides, and repairs itself. When they proliferate, the receptors tell
Reading Comprehension Question. This is a description of one type breast cancer. One in five invasive breast cancers is HER2-positive, making this one of the more common breast cancer subtypes in the United States. HER2-positive cancers are ER- and PR-negative and human epidermal growth factor receptor 2 (HER2)-positive. HER2-positive breast cancer cells carry too many copies of the HER2 gene, which makes HER2- protein receptors, found on breast cells. When they work normally, HER2 receptors control how a healthy breast cell grows, divides, and repairs itself. When they proliferate, the receptors tell
Chapter3: Cells
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One in five invasive breast cancers is HER2-positive, making this one of the more common
breast cancer subtypes in the United States. HER2-positive cancers are ER- and PR-negative
and human epidermal growth factor receptor 2 (HER2)-positive.
Reading Comprehension Question. This is a description of one type breast cancer.
HER2-positive breast cancer cells carry too many copies of the HER2 gene, which makes HER2-
protein receptors, found on breast cells. When they work normally, HER2 receptors control how
a healthy breast cell grows, divides, and repairs itself. When they proliferate, the receptors tell
the cells to divide and grow rapidly and without control. That is because their cells absorb too
much of a substance called human epidermal growth factor 2, which energizes cell growth.
Doctors often test breast cancer tissue for excess HER2-positive genes to determine whether
the patient may benefit from targeted therapy options, which are designed to block HER2 from
energizing cancer cell growth.
Source: https://www.cancercenter.com/cancer-types/breast-cancer/types/breast-cancer-
molecular-types
Based on the information above only. Answer these questions.
1. What is the normal function of HER2 gene
2. How does HER2 gene cause Her2-type breast cancer
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