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In your own words, explain how cancer cells differ from normal cells in regard to the following:
Apoptosis
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- Cell specializations are usually a modification or elaboration of one of the basic cell functions. (True or fa1se?)In your own words, explain how cancer cells differ from normal cells in regard to the following: Cell to cell communicationIn your own words, explain how cancer cells differ from normal cells in regard to the following: Molecular controls of the cell cycle (include Cdk and Cdk/cyclin complexes, p53 gene/protein, Rb gene/protein in response)
- How is apoptosis involved in cancer? Describe the role of apoptosis in cancer and identify what molecules are involved. Cite your references. asap.Which component of cell division machinery is frequently targeted by anti-cancer drugs? Can you explain the common side-effects of chemotherapy (e.g. hair loss, mucositis) based on this information?Compare the characteristics of highly proliferating normal cells (including cells of the hair follicles, gastrointestinal tract, and bone marrow) with the characteristics of highly proliferating cancerous cells
- Which is true for cancer cells: 1) Cell death occurs after a determined number of cell divisions 2) Contact with other cells reduces chance of cell division 3) Cell division occurs in the presence of stop signals.Cancer is a complicated series of diseases characterized by over-proliferation of cells within a tissue. While in some instances the primary tumor is the ultimate cause of death, in many cases the primary tumor metastasizes, or moves, through the lymph system to invade other tissues. The migration of tumor cells requires changes in the adhesion properties of the cell that allow it to move and invade more readily. There are several molecules involved in cell-to-cell connections and cellular architecture: laminins, matrix metalloproteinases, cadherins, and integrins. While mutations in genes that control the cell cycle or recognize DNA damage are the causes of tumor cell formation, tumor cell spread to other tissues may be caused by mutations in the genes the code for these extracellular proteins. The loss of cellular connections, cellular identification and signaling, and tissue structure may lead to the release of expanding tumor cells into the circulatory and lymphatic systems. Once…Explain the property that prevents normal cells from becoming cancerous.
- In your own words, explain metastasis and why this process is important in the prognosis of a patient, and is this an easy and efficient process for cancer cells, why or why not?Discuss why certain cell types are less likely and others are more likely to develop cancer than others.Explain how the cell cycle of a cancer cell is abnormal.