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Question 38
The constant region of each heavy chain determines the class of the heavy chain.
True | |
False |
Question 39
The extensive variety of MHC proteins is apparent at a population level.
True | |
False |
Question 40
the immunoglobulin sequences involved in antigen binding is situated in:
|
The constant region of the antibody |
|
The hyper-variable region of the antibody |
|
C terminal of the antibody |
|
Area close to disulfide bridges |
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- Which of the following primary sequence of an antibody has the greatest diversity? Question 13 options: All regions are similarly conserved. Fab region Complementarity-determining region (CDR) Fc region receptor binding domain (RBD)Question 10 of 14 Which of the following are true about MHC class I and MHC class II peptide loading? Select all that apply. MHC class I peptide loading occurs in four steps. Peptide loading of class I molecules generated from intracellular proteins occurs in the endoplasmic reticulum. ⒸMHC class II molecules are loaded before they are part of a vesicle capable of fusing with a phagolysosome. Peptide loading of class II molecules occurs later in the secretory pathway than that of MHC class I molecules.QUESTION 4 A person with agammaglobulinemia: cannot produce antibodies cannot produce interferons does not have functional cell-mediated immunity makes too many antibodies
- What is the minimum number of reactive antigen-positive and non-reactive antigen-negative panel cells that must be present in order to identify a red cell antibody with statistical confidence? Please select the single best answer Two Three Five TenQuestion 9 of 14 Which of the following acts as a signal for the dendritic cell to begin cross-presentation? Presence of self-reactive CD4 T cells O Expression of endoplasmic reticulum (ER) chaperones calnexin and calreticulin O Phagocytosis and processing of extracellular antigens O Cytokine release following the activation of engaged CD4 T cells Question 10 of 14 Which of the following are true about MHC class I and MHC class II peptide loading? Select all that apply. MHC class I peptide loading occurs in four steps. Peptide loading of class I molecules generated from intracellular proteins occurs in the endoplasmic reticulum. MHC class Il molecules are loaded before they are part of a vesicle capable of fusing with a phagolysosome. Peptide loading of class Il molecules occurs later in the secretory pathway than that of MHC class I molecules.term can only be used once. anes, secretions [Choose J [Choose] ainst infection in the blood luid internal defenses humeral response nd against infection in the body colls cell-mediated response barrier defenses
- Question 3 Which of the following statements about TI-1 antigens is FALSE? They require T cell help They do not result in memory cells They do not result in class switch or somatic hypermutation They contain a mitogen Question 4 What transcription factor is used to identify Treg celis? A) FoxP3 CTLA4 GATA3 D BCL6You can choose one or more than one option Antibodies: IMMUNOLOGY basic have two identical antigen-binding sites. consist of two identical heavy chains and two identical light chains. are secreted by plasma cells are produced by T lymphocytes during adaptive immune response can bind their constant heavy chain region to phagocytes Which of the following proteins are transmembrane proteins? CELL BIOLOGY basic integrin oestrogen receptor phospholipase C adenosine triphosphate (ATP) synthase growth factor receptor What are the correct statements? MOLECULAR BIOLOGY advanced A mutation located within a promoter can change the gene expression. An mRNA can be differentially spliced according to the tissue. RNA transcribed by the RNA polymerase II are translated The end of the transcription process requires a specific DNA sequence A reverse transcriptase can polymerise either a DNA or an RNA strand. Which of the following cells kill other cells by exocytosis of…Which statement about antibodies is INCORRECT? Question 16 options: Antibodies can be both soluble and membrane-bound. Antibodies bind to antigens via induced fit. Antibodies never release antigens once they are bound together. More than 100 million different antibodies can be produced in humans. Antibodies typically bind to antigens more strongly than enzymes bind to substrates.
- I understand what autoantibodies are, but are ANAs the same thing as autoantibodies, or is there a difference between them. anti-nuclear antibodies (ANAs)The indirect immunofluorescence ("fluorescent Ab") test shown below is performed to test for: + AA T. pallidum from Specific antibodies laboratory stock in serum of patient Antibodies bind to T. pallidum + ㅅ Fluorescent dye-labeled anti-human immune serum globulin (This will react with any immunoglobulin) Da Fluorescent spirochetes (see Figure 3.6b) None of the other four answers are correct The presence of T. pallidum bacteria in the patient's blood Whether the patient has made antibodies against other human antibodies Immunologic evidence of current or past infection with T. pallidum (i.e., Ab against T. pallidum) Growth of T. pallidum in culture from a syphilis patientYou are interested in performing indirect immunofluorescence light microscopy to observe the localization of the catalase enzyme in the cultured HeLa cells, obtained historically from the cervical tumor of Henrietta Lacks. You were going through the lab stock and found a few primary and secondary antibodies. Which of the following secondary antibody can you use in your experiments? O All of the mentioned antibodies can be used in the experiment Goat anti-human antibody conjugated to 10 nm gold Goat-anti-human catalase conjugated to 10 nm gold O Human anti-catalase antibody conjugated to fluorescent rhodamine Goat anti-human antibody conjugated to fluorescent rhodamine