Maple syrup urine disease may be due to an autosomal recessive mutation. Data indicate that the prevalence of this pathology is approximately 5 in 1,000,000. What is the probability that an individual is a healthy carrier of the defective allele? □about 1/1000 no correct answer ☐about 1/223 about 1/258 about 1/129 about 1/111
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- I need help in table 2 & 3 please Table 1 Phenotype O E O-E (O-E)^2 (O-E)^2 /E Disease, Male 304 433.875 129.875 16789.68 38.69 Disease, Female 267 433.875 166.875 26855.01 61.89 WT, Male 285 144.625 140.375 19705.14 136.25 WT, Female 301 144.625 156.375 24453.15 156.37 Total 1157 1157 393.20 DF 3 p-value 7.84 Expected progencies as per SLR MOI’s = 1:1 for both male and female Phenotype O E O-E (O-E)^2 (O-E)^2 /E Disease, Male 304 289.25 14.75 217.56 0.75 Disease, Female 267 289.25 22.25 495.06 1.85 WT, Male 285 289.25 4.25 18.06 0.06 WT, Female 301 289.25 11.75 138.06 0.46 Total 1157 1157 3.12 DF 3 p-value 7.84 Progenies are following SR MOI’s that parents have genotypes and progenies in ratio 1:1 In Table 2,…the offspring ès) can often be autosomal I 1.1 III ad amalg od no IV 9 OTO 5 0000 anivellor and goje If individual 2 were to marry a woman with no family history of the disease, which of the following would most likely be true of their children? a. All of the children would have the disease. b. None of the children would have the disease. c. Only the sons would have the disease. d. All of the sons would be carriers of the disease. e. None of the daughters would be carriers of the disease.15 1 point What is the most likely mode of inheritance of the disease depicted in the following pedigree? ||| IV 1 autosomal dominant autosomal recessive 2 N 1 2 2 3 3 4 3 4 5 --D
- Listen A dominant mutation (B) on the X chromosome causes eyes in fruit flies to be oval. The recessive allele (b) causes the eyes to be round. Just as in humans, in fruit flies XY is male and XX is female. You take a male with oval eyes and cross it to a female with round eyes. What percent of the male offspring with have oval eyes? 100 % O 50% 75% 25 % 0% Question 15 Listen A dominant mutation (B) on the X chromosome causes eyes in fruit flies to be oval. The recessive allele (b) causes the eyes to be round. Just as in humans, in fruit flies XY is male and XX is female. You take a male with oval eyes and cross it to a female with round eyes. What percent of the female offspring with have oval eyes? 100 % 50 % 75 % 0% 25 %d Dd 501. s0% 5. Another type of blood disorder is hemophilia, which is an X linked disorder caused by a recessive allele. Like VWD, this disorder interferes with the protein that is involved with blood clotting. Known as "bleeder's disease" because any minor injury can become life threatening. This disorder is considered more severe than VWD. In both cases there are versions of the disorder that can be less and more severe depending on which protein or clotting factor is affected. Normal XHY Normal X"Xh Carrier XhY Hemophilia Bourthelesm X"Xh Hemophilia If a woman is a carrier, what percentage of her SONS will have the disorder? How many (%) of their sons will have hemophilia? How many (%) of their sons will be normal? How many (%) of their daughters will be normal? 6. A man who has hemophilia marries a normal woman (not a carrier)... How many (%) of their sons will have hemophilia? How many (%) of their daughters will be carriers 7. A woman who is a carrier marries a man with…Edio | Course Student Lesson Using the letter T to represent t x + days/1089940/lessons/1533883/variants/2273231/take/14/ O Alert 1 of 1: Instructional Technology Subsidy Úp. DISMISS * Practice MULTIPLE CHOICE Using the letter T to represent the trait, what is the genotype for individual 7? TT TE it is impossible to determine from this picture Atempe t of 2 683838886 0888.o S of & Total Questions Answered A Changes Saund 21°F Sunny
- A rara autosomal dominant disease is known to have 80% penetrance. If individual II1 has a child, what is the probability that this child will show the symptoms of this disease? II 20% 40% 50% 80% 000094. A recently married couple come to the physician for counseling prior to conception. They are concerned about the risk for cystic fibrosis in their future offspring because one of their best friends has a child with this disease. Both partners are healthy and have no family history of cystic fibrosis. Cystic fibrosis is an autosomal recessive inherited disorder and has a heterozygote frequency of approximately 1/25. Which of the following best represents the risk for cystic fibrosis in each of this couple's future offspring? OA) 1/625 B) 1/1250 C) 1/2500 D) 1/5000 E) 1/10,000A prospective groom, who is normal, has a sister with cystic fibrosis (CF), an autosomal recessive disease. Their parents are normal. The brother plans to marry a woman who has no history of CF in her family. What is the probability that they will produce a CF child? They are both Caucasian, and the overall frequency of CF in the Caucasian population is 1/2500—that is, 1 affected child per 2500. (Assume the population meets the Hardy–Weinberg assumptions.)
- A prospective groom, who is unaffected, has a sister with cystic fibrosis (CF), an autosomal recessive disease. Their parents are normal. The brother plans to marry a woman who has no history of CF in her family. What is the probability that they will produce a CF child? They are both Caucasian, and the overall frequency of CF in the Caucasian population is 1/2500—that is, 1 affected child per 2500. (Assume the population meets the Hardy– Weinberg assumptions.)Match the following terms with their correct definitions. A change in a gene that causes it to produce no protein. A loss-of-funtion in one allele that is uominant because the wild type allele alone does not produce enough protein to serve its typical role. 1. Loss-of-function mutation 2. Null mutation 3. Gain-of-function mutation A change in a gene that causes it to produce less protein or protein that is not able to serve its typical role. 4. Haploinsufficiency A change in a gene that causes it to produce increased protein or protein that takes on a new role.Edio | Calendar X Edio | Student Da x days/1089977/lessons/1533969/variants/2439102/take/10/ A Q TEXT ANSWER The inheritance patterns for some traits in guinea pigs are listed in the table below. 1. Identify the phenotype of a guinea pig with the genotype HhBBrr. 2. Using the allele symbols in the table, identify the genotype of a guinea pig that is recessive for hair length, heterozygous for hair color, and homozygous dominant for hair texture. Trait Dominant Allele Recessive Allele hair short (H) long (h) length hair color black (B) white (b) rough (R) smooth (r) hair texture BIUG X₁ X¹ EEAA H Normal : √x Enter your answer here ŏooooo Questions Answered 中山川 Ω Ο Τ Edio | Calendar X RepostExchange X Practice All Changes Saved Continue