Q: What is inflammatory bowel disease?
A: Inflammatory Bowel Disease (IBD) describes a group of disorders in which intestines become inflamed.…
Q: Is the pancreas an exocrine gland or an endocrine gland?
A: The exocrine gland is associate organ settled within the abdomen. It plays a vital role in…
Q: What is the correlation between destruction of parietal cells and Vit B12 deficiency?
A: Animal physiology and human anatomy is the branch of science that studies the form and function of…
Q: what will happen if there is an accumulation of acetyl CoA in the liver mitochondria?
A: Acetyl coenzyme A is a thioester between the acyl group carrier, acetic acid, and a thiol that acts…
Q: Describe the mechanisms controlling the pancreatic secretion ofHCO32 and enzymes?
A: The pancreas is a glandular organ present in the abdominal cavity of the vertebrate. It has both…
Q: How does insulin resistance lead to failure of the pancreatic β cells that results in type 2…
A: Insulin resistance in the body is the resistance from the chemical insulin, bringing about expanding…
Q: What is the function ofvitamin E? In which foods canit be found?
A: Vitamins are any of several organic substances that are necessary in small quantities for normal…
Q: There are more mitochondria than average in pancreatic acinar cells. Suggest a reason for this.
A: Pancreatic acinar cells secrete fluid and digestive enzymes. Both types of secretion are activated…
Q: Why is it important to learn more about the causes of colon cancer? And why is colon cancer…
A:
Q: Exlplain the cause pancreatic cancer ?
A: Answer: Introduction: Pancreatic cancer take place if cells in the pancreas undergoes mutation in…
Q: What are SER? What are the functions of SER?
A: The endoplasmic reticulum (ER) is generally State to define as the form of a three-dimensional…
Q: Define the pancreatic islet ?
A: The primary unit of life is the cell. Based on the number of cells an organism may be unicellular or…
Q: What is the function of beta cells of pancreas?
A: Pancreas located in the abdomen. It performs two functions in the body 1. It secret digestive…
Q: Why are SGLT1 inhibitors drugs able to lower blood glucose and why do they cause diarrhea?
A: SGLT1 stands for sodium glucose cotransport 1.
Q: What are the causes of Polyps and Colon Cancer ?
A: Polyps are tissue growths that most often look like small, flat bumps or tiny mushroom-like stalks.…
Q: in regards to pancreatic cancer, what chemical process are disrupted at the cellular level, that…
A: Pancreatic cancer is a type of cancer in which malignant cells form in the tissues of the pancreas.…
Q: which two pancreatic hormones are the major drivers of glucose homeostasis? where does each come…
A: Pancreas are endocrine glands that secrete hormones that play an important role in glucose…
Q: Why certain individuals are susceptible to certain diseases, especially chronic conditions such as…
A: In biology, the term susceptibility refers to the state of lack of ability to resist some extraneous…
Q: Gastrinomas are tumors of the GI tract that secrete gastrin, leading to very high plasma…
A: Gastrinomas are the tumor that usually occur in pancreas and duodenum.
Q: what is the role HGF in pancreatic cancer?
A: * HGF is also known as Hepatocyte growth factor or scatter factor which is an paracrine cellular…
Q: Explain why the pancreas is both an endocrine and anexocrine gland.
A: The glands of the endocrine system are known as endocrine glands which produce chemical molecules…
Q: What effect does cortisol have on the liver?
A: Cortisol is a corticosteroid hormone that comes under the class of glucocorticoids. This hormone is…
Q: What is the root cause of Duchenne muscular dystrophy? What is the normal function of dystrophin?
A: Introduction: The dystrophin gene is located on the short arm of the X chromosome. If absent, the…
Q: Give an example of the nonproteolytic enzymes secreted by the pancreas?
A: Pancreas It develops from endoderm, which is soft, lobulated and elongated organ situated between…
Q: What types of normal cells typicallyhave insulin receptors?
A: Insulin is a hormone secreted by the beta cells present within the pancreatic islets of Langerhans.…
Q: State four causes of folate deficiency
A: Folate is important for : Formation of DNA Repair of DNA production of red blood cells
Q: How does insulin resistance or the lack of insulin contribute to the typical symptoms of diabetes?
A: Insulin is a peptidal hormone, which helps in the control of glucose levels in the body.
Q: Why is amyloid toxic to cellsand how does it contribute toneurodegenerative diseases such…
A: Pathogenic amyloids formation takes place, when healthy proteins lose their normal structure…
Q: Which region of the pancreas is highlighted?
A: Pancreas is a long, flattened gland that serves two purposes: it is an important component of the…
Q: If pancreatic cancer occurs, explain the way it reaches the ovary.
A: Pancreatic cancer is a type of cancer in which malignant cells form in the tissues of the…
Q: Which lysosomal storage disorder do not causes mental retardation?
A: Lysosomal storage disorder occurs due to accumulation of sphingolipids in the different cells and…
Q: By what sweet patato is modified?
A: Plants mainly refer to multicellular plants that have ability to perform photosynthesis and belong…
Q: If removal of the pancreas results in a variety of metabolic disturbances that ultimately lead to…
A: Pancreas is one of the retroperitoneal organ having both exocrine and endocrine function. Loss of…
Q: What is the function of alpha cells of pancreas?
A: Pancreatic islets, likewise called the islets of Langerhans, are areas of the pancreas that contain…
Q: How was insulin obtained before the advent of rDNA technology?What were the problems encountered?
A: Insulin is a protein hormone that is used as a medication to treat high blood glucose. It helps…
Q: How are pancreatic proteolytic enzymes activated in the small intestine?
A: The word intestine is derived from the Latin root that means "internal," and the two organs combined…
Q: Why do individuals with cystic fibrosis have pancreatic insufficiency?
A: Cystic fibrosis is caused by the a defect in the CFTR gene. This mutation in the gene causes cells…
Q: in regards to pancreatic cancer, what mechanisms fail at the cellular level that disrupts…
A: The pancreas has key functions in the guideline of macronutrient processing and thus…
Q: Is there any epithelial surface modification in the pancreas? What is it?
A: Epithelium is the covering which forms the outer layer of most of the organs. Epithelial surface…
Q: P65:: Which vitamin deficienciency causes carcinoid syndrome?
A: Carcinoid syndrome is a a neuroendocrine syndrome occur most commonly in the gastrointestinal tract…
Q: How does insulin resistance lead to failure of the β cells of the pancreas that results in type 2…
A: Insulin is a hormone that helps to regulate the glucose metabolism secreted from the beta cell of…
Q: What is the most common cause of liver cancer?
A: A tumour that can develop anywhere in the liver is called liver cancer. On the top right side of…
Q: What is the function of delta cells of pancreas?
A: A hormone is a molecule that works on specific tissues and organs to do an action. The pancreas is…
Q: What is the effect of overnutrition on the pancreas?
A: The pancreas is a digestive and endocrine system organ found in animals. It is a gland that is…
In regards to pancreatic cancer, are there any genetic mutations that lead to the condition?
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- What is the sequential pattern of mutations commonly observed in the development of colorectal adenocarcinoma, and how do these genetic alterations contribute to tumorigenesis and disease progression? Discuss key genes and signaling pathways involved, including APC, KRAS, and TP53 and describe how these mutations disrupt normal cellular functions and promote uncontrolled growth in colorectal cancer.What is the importance ofKRAS gene in the development of colorectal cancer. ?what is The genetic basis for chronic myelogenous leukemia ?
- The development of colon cancer is particularly well- studied, and often has a predictable order of mutations. Briefly describe the most common steps in the progression of colon cancer in the order of key genes mutated.Neurofibromatosis type 1 (NF1) is an inherited is an inheritent dominant disorder. The phenotype usually involves the production of many skin neurofibromas. Answer the following questions about the disorder: a) Are the NF1 neurofibromatosis-causing mutations that are inherited by affected children from affected parents likely to be loss-of-function or gain-of-function mutations? b) Neurofibromin, the protein product of NF1, is associated with the Ras protein. Ras is involved in the transduction of extracellular signals from growth factors. The active form of Ras is complexed with GTP; the inactive form is complexed with GDP. Would the wild-type neurofibromin protein favor the formation of Ras-GTP or Ras-GDP? c) Which of the following events in a normal cell from an individual inheriting a neurofibromatosis-causing allele could cause the descendents of that cell to turn into a neurofibroma? i. A second point mutation in…What is the physiological effects of pancreatic cancer at the cellular, tissue and organ system? What mechanisms fail at the cellular level that disrupts homeostasis? Are there any genetic mutations that lead to the condition? What are the effects on the body as a result of this disease at the cellular level that leads to failure of the organ system? The discussion here should involve an account of how the disruption in the functioning of the organs and tissues in the specific system you are researching, affect other systems. what chemical process are disrupted at the cellular level, that leads to the organ/system not functioning leading to the disease conditions. Did any gene mutations occur? If so at which location on the chromosome etc?
- Although cancer is not a contagious disease in humans or other vertebrates, there have been rare cases in which cancers have spread from one organism to another. Describe three cases of these contagious cancers and what conditions might have led to their appearance. For an introduction to this topic, see http:// www.cancer.org/cancer/cancerbasics/is-cancer-contagious.What are Malignant tumors ?Why is this disease sometimes misdiagnosed as leukemia?
- Certain types of cancer can lead to humoral hypercalcemiaof malignancy. True or false?What is a good conclusion for causes of colon cancer ?1. the wnt story:- a) Discuss the role of Wnt pathway in the normal development of epithelia within the colon – stem cells, differentiated epithelia, and shedding epithelia. b)Then discuss how this path gets altered in the familial cancer FAP – familial adenomatous polyposis? How does it get impacted in non-hereditary colon cancer? Your discussion should explain how the altered wnt path leads to hyperplastic epithelia