Find the starting materials of this compound via retrosynthetic approach (4 marks) Further synthesis the compound using any of the starting material from (a) by displaying its mechanism (6 marks) Multistep process is involved in the synthesis of an Aldol Condensation product (D). Starting with Benzene, complete the following reaction given the reaction conditions. Show by way of mechanism how A, B, C and D are derived (10 marks) i H D = . heat CI ALC13 A- NaOH, B + C A CH31 CH3
Q: 2.49 Write the equality and two conversion factors, and identify the numbers as exact or give the…
A: Approach to solving the question: Detailed explanation: Examples: Key references:
Q: Do it.
A: **A) Number of Rings Undergoing Electrophilic Aromatic Substitution (EArS):** In the given…
Q: Phosphine, PH3, undergoes a first-order decomposition into phosphorus, P4, and hydrogen at 680 °C.…
A:
Q: Classify each species as a Lewis Acid or a Lewis Base. CN Fe2+ 1. Lewis Acid H₂O 2. Lewis Base AlBr3
A: Step 1: A substance with vacant orbital and accepts the donated valence electrons is a Lewis acid…
Q: Heating D-altrose with dilute acid produces a nonreducing anhydro sugar (C6H1005). Methylation of…
A: The objective of the question is to understand the structure of the anhydro sugar formed by heating…
Q: None
A: In the context of the provided reaction, involving NBS (N-bromosuccinimide), light, and bromine…
Q: i need solution please help me my question answer.
A: The objective of this question is to calculate the molar concentration of glucose in a solution…
Q: 4.00 g NaOH(s) (39.996 g mol–1) dissolves in 100.0 g of water in a constant–pressure calorimeter.…
A: Step 1:Moles of NaOH= molarmassmass= 39.996g/mol4.00g= 0.100 mol.Given,…
Q: 2. In the synthesis of peptides, carboxylic acids are condensed with amines in the present of a…
A:
Q: Use the References to access important values if needed for this quest Hybrid orbitals are formed by…
A: a) The electron pair geometry of this molecule is Trigonal Bipyramidal The geometry of electron…
Q: an efficient synthesis for each of the following compounds using the 22.39 Propose acetoacetic ester…
A: Step 1: a)1. Acetoacetic ester with sodium ethoxide, deprotonates the acidic hydrogen forming…
Q: Predict the products for the following reactions. heat light
A: Step 1: Claisen-Cope rearrangement: Allyl vinyl ether on heating undergoes [3,3]-sigmatropic…
Q: Draw the major product of this aminolysis reaction. Ignore inorganic byproducts. 1. excess NH(CH3)2…
A:
Q: * What is pesticides * What is pesticides about and who/what does it affect? * How is pesticides…
A: “Since you have posted a question with multiple sub parts, we will provide the solution only to the…
Q: 2. In each synthesis, either the reagents or products are missing. Fill in the missing reagents or…
A: Step 1: Step 2: Step 3: Step 4:
Q: A weak base has a K₁ of 5.6x104, determine the pK₁ of the base. 3.25 7.64 10.75 6.36
A: The pKb of a base is the negative logarithmic of Kb value of the base. pKb = - log Kb As per the…
Q: 1. Propose reagents for the following reaction. (Hint: Only one of the two ways of adding a carbon…
A: SYNTHESIS:EXPLANATION: Using Mg/THF in the first step the grignard reagent is produced. It acts as…
Q: Using curved arrows, please give a mechanism to explain the following elimination (E1) reaction. H3C…
A: Step 1: Explanation:Alkyl halide, when heated in the presence of ethanol, undergoes elimination…
Q: None
A: The solubility product (Ksp) is calculated by multiplying the concentrations of lead ions and…
Q: You are burning organic brush in your backyard. The molecular formula for the brush is: C204 H325…
A: Now, let's perform the calculations: b. Number of moles of compost that burns:We'll first find the…
Q: A fluoride ISE immersed in 1 x 10•2 mol dm solution of sodium fluoride gives a potential of 35,2 mV…
A: The objective of the question is to find the concentration of fluoride ion in the toothpaste using…
Q: None
A: 46. The proton with the highest chemical shift in the molecules is the proton that is directly…
Q: None
A: Part 2: Explanation:Step 1: Identify the original molecule's skeletal structure.The original…
Q: When designing a consumer product, it is desirable for it to have a two-year shelf life. Often this…
A: Step 1: Step 2: Step 3: Step 4:
Q: 2. Which of the following compounds would be considered anti-aromatic?
A: Step 1:Hückel's rule for aromaticity, antiaromatic and non aromatic compound are :-…
Q: Consider the reaction:CaCO3(s)CaO(s) + CO2(g)Using standard thermodynamic data at 298K, calculate…
A: Step 1:Given reaction:CaCO3(s) → CaO(s) + CO2(g) ΔH0=∑ΔHf0(products)−∑ΔHf0(reactant)…
Q: 12. In the hydrogenation reaction shown, which of the alkenes below would yield the observed…
A: In a hydrogenation reaction involving H2 Pd/C, both the hydrogen atoms attach on the same side. This…
Q: H₂N NH2 + HCl
A: The reaction is an acid-catalyzed amide hydrolysis. Amide typically is resistant to hydrolysis even…
Q: None
A: If what you mean is the Vander Waals constant then below are the literature b value for each gas.…
Q: None
A: Step 1: The nucleophilic attack i.e. attack of -OMe on the electrophilic centre of acid chloride.…
Q: None
A: Step 1:ionic bond is formed due to difference in electronegativity like NaClcovalent bond is formed…
Q: Copper normally melts at 1085 °C with an enthalpy of melting of 13.05 kj/mole. The constant molar…
A: To estimate the change in melting point (ΔT) of copper when the pressure (ΔP) is increased by 10 atm…
Q: CH3 -CH2CHOCH 3 A How many signals would be observed in the proton decoupled 13C NMR spectrum of…
A: There would be 4 signals observed in the proton decoupled 13C NMR spectrum of compound A. The carbon…
Q: Modify the given copy of the starting material to draw the major radical bromination product(s),…
A: This is free radical addition of HBr to an alkene. Generally, Br adds to the less substituted…
Q: 25. A 2L sample of mineral water was titrated with EDTA to determine its hardness in terms of ppm…
A: Step 1:Step 2:
Q: The chart below shows the first five successive ionizations of element M. What is the formula of the…
A: The energy required to remove a valence electron from a gaseous atom or ion is called ionization…
Q: Consider the reactionCH4(g) + H2O(g) 3 H2(g) + CO(g)Using the standard thermodynamic data in the…
A: do leave a thumbs-up, as it motivates us to assist you better and faster. Thank You.
Q: In class we said that an approximate form for the bond stretch potential is V = k. -stretch (r-r)².…
A: The objective of the question is to derive an expression for the root mean squared (RMS) stretch…
Q: Show work, thank you!
A: To calculate the equilibrium constant (K), we can use the relationship between Keq and ΔG°: ΔG° =…
Q: Imagine the main chain of a protein bends back on itself, so that two amino acid residues R₁ and R₂…
A: Sure, let's delve into each interaction:1. Valine - Alanine (Hydrophobic Interaction): Both valine…
Q: 2. Standard ... 3. AS surrou... 1req Consider the reaction 4. AG° = AH°... M 5. AG: Pre... 1req 6.…
A: Step 1: Step 2: Step 3: Step 4:
Q: Consider the reaction: 2NH3(g) + 202(g) → N₂O(g) + 3H₂O(!) Using standard thermodynamic data at 298…
A: To find the entropy change for the surroundings, use the relationship between heat (q in joules) and…
Q: I2 (aq) + CH3COCH3 (aq) HI (aq) + ICH2COCH3 (aq) Iodine in solution has a yellow-brown color,…
A: To calculate the initial concentration of the reactants for experiments 1 to 4. Given the following…
Q: Each of the insoluble salts below are put into 0.10 M hydroiodic acid solution. Do you expect their…
A: 1. **Nickel(II) sulfide (NiS)**: - NiS is slightly soluble in water. Hydroiodic acid adds a…
Q: None
A: Approach to solving the question: Detailed explanation: Examples: Key references:
Q: 11. Provide a stepwise synthesis for the following.
A: Step 1: Alkenes on reaction with hydrogen halides in presence of peroxides to give alkyl halides,…
Q: provide a name for the following compound.
A:
Q: Payalben
A: The objective of this question is to calculate the change in enthalpy (ΔH) for a reaction given the…
Q: What is the final temperature when 100.0 g of Al (s = 0.900 J g–1 °C–1) at 0.0°C is placed in…
A:
Q: The surface temperature of Venus is about 1050 K, and the pressure is about 75 Earth atmospheres.…
A: The objective of the question is to calculate the standard molar volume of a gas on Venus given the…
Unlock instant AI solutions
Tap the button
to generate a solution
Click the button to generate
a solution
- Use the reaction given below to answer the following questions. A CH₂OH B H₂O+ C + CH3NH3* D a) What are the approximate pKas of compounds A and B? b) The reaction given above is irreversible. Give a detailed explanation of the reaction and reaction mechanism. Your explanation should indicate your knowledge of the reactivity of carboxylic acid derivatives.Help meThis reaction shows that an aldol-type reaction can be performed with a deprotonated imine as the nucleophile. On hydrolysis, the product is the normal B-hydroxycarbonyl compound. Notice that LDA is used H3C N. 1. LDA Но ? as the base instead of HO¯. H3C H. H. (a) Explain why HO¯ cannot be used as a base for this 2. reaction. (b) Provide a detailed mechanism for this reaction, including the structure of the intermediate species not shown.
- (a) Benjamin List and David W.C. MacMillan have been awarded 2021 Nobel Prize in Chemistry, for their development of a new type of catalysis. Amino acid proline, acting as the catalyst, has successfully catalyzed an aldol reaction with the formation of one mirror image of the product much more than the other one. Below is the aldol product: OH 4-hydroxy-3-methylpent-2-one The compound has two chiral carbons. Show two of the chiral carbons using asterisk signs and draw one of the chiral carbons in enantiomeric forms. Apply (R) and (S) configurations for the enantiomers based on the Cahn-Ingold-Prelog system.(a) Benjamin List and David W.C. MacMillan have been awarded 2021 Nobel Prize in Chemistry, for their development of a new type of catalysis. Amino acid proline, acting as the catalyst, has successfully catalyzed an aldol reaction with the formation of one mirror image of the product much more than the other one. Below is the aldol product: OH 4-hydroxy-3-methylpent-2-one The compound has two chiral carbons. Show two of the chiral carbons using asterisk signs and draw one of the chiral carbons in enantiomeric forms. Apply (R) and (S) configurations for the enantiomers based on the Cahn-Ingold-Prelog system. (b) Give the product and the type of mechanism of the reaction of hydrosulfide (HS) with (R)- 2-iodopentane. Give the stereochemistry resulting from the product.Retrosynthesis For each of the following, perform a retrosynthetic analysis and then design a synthesis to go from the reactant(s) to the product(s). You are free to use any reagents or reactants if the listed reactant is incorporated or unless otherwise specified. 7) Synthesize: From: OH
- • Using aldol or crossed aldol condensation, suggest a synthesis of the following compounds: a b مليمت H3C H3C CH3 H3C ge H SavedQI/ Arrange and give reason the following sets of compounds in order of: 1) Increasing acidity CH Ph OCHCH, (a) (b) (c) (d) 2) Give more yield in cross Aldol condensation p-methyl benzaldehyde , p-methoxy benzaldehyde , benzaldehyde , p-nitro benzaldehyde 3) Stability of carbanion ion CH3 CN . CH3-C-OCH3 CH3-C-CH, , CH3NO2Write out the interpretation of your results in paragraph form. You can use the following questions to guide your discussion. • Is your percent yield within reason of what you would expect? Explain your answer. • Comment on purity of the recrystallized product based on melting point comparison to literature value. • Complete the following reaction: a b H3C • Using aldol or crossed aldol condensation, suggest a synthesis of the following compounds: H3C CH3 H H3C. come NaOH heat H3C. CH3 Saved
- Which of the following best represents a mechanistic step in the acid-catalyzed hydrolysis of acetonitrile? А) НС —СEN: Н-ӧ: Н В) НС —СN-H Н-ӧ: н С) НС —СN: н ӧ: D) H3C-C=N: Н-ӧ: нNitroalkanes are about as acidic as ketones and aldehydes. Nitroalkanes can also be utilized in reactions similar to the Aldol reaction (a reaction termed a Henry reaction). a) Rationalize why nitroalkanes are more acidic than alkanes. b) Provide a mechanism for both steps of the following Aldol-like (Henry) reaction. base conjugate base base less stable conjugate base NO2 (b) NO2 но NO2 - H20 H. H. кон O=ZPredict the intermediate (A) and Reagent (B) in the reaction sequence below.