Discuss the operation of Na+ - K+ pump in further detail (2 pages including a few figures, if necessary). In particular, how does it recognize and regulate the level of [Na+] and [K+] both inside and outside.
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- • Estimation of the Water Potential (Ψw) of Storage Tissue by Volume Change Method Observe these experiments in these links: https://www.youtube.com/watch?v=jTDATlaBV-o https://www.youtube.com/watch?v=k1O9jBHgsxs Estimates of water potential of various tissues have been obtained after equilibrating the tissues in solutions of different osmotic potentials. The principle depends upon finding the concentration of sucrose that would cause no change in weight of the tissue before and after an incubation period in the solution. This concentration may be assumed to have a water potential equal to that of the tissue.Ca2+ Using Figure 8.1, answer the following questions: 6) What is occurring in Step 2 of the figure above, and how is that process originated? 6) 7) Identify the structures on the postsynaptic membrane that bind with the neurotransmitter 7) in Steps 4 and 6 of the figure above, and indicate their function. 8) In the figure above, the overall function of Steps 6-8, which occur simultaneously, is to 8) 9) Based on the figure, describe the two possible mechanisms whereby Step 5 can occur on the postsynaptic membrane. 9) 10) Based on the figure, identify the structure in Step 6, if this presynaptic neuron is cholinergic. What if the neuron is adrenergic? 10)Problem: The treatment of severe hypernatremia can be challenging, especially in patients with preexisting conditions that may seem to limit therapeutic options. Such a situation recently resulted in an ill-conceived decision to give sterile water for injection IV to an elderly patient who had been admitted to an ICU with pneumonia and severe hypernatremia. The physician did not want the patient to receive any further infusions containing sodium. But the patient also was severely hyperglycemic. The physician's concern with giving sodium or dextrose to a patient with high blood sugar led to an order to change the patient's IV to "free water" at 100 mL/hr. "Free water" refers to water not associated with organic or inorganic ions. Because hypernatremia usually results from a deficit of "free water," it's likely that the physician intended to replace this loss when he wrote the order. Water can be replaced orally, however, it should never be given IV without additives to normalize…
- hi can you find the maximum binding capacity(b max) using the tableexplain why>? • Ciprofloxacin (Cipro) is a fluoroquinolone antibotic. Itselimination half life and the apparnt volume of distribution are 4h and 2,25 L/kg respectively. The IV bolus administration ofciprofloxacin yielded the plasma concentration 1,048microgram/mL at 6 h. Determine the administered dose ofCipro?a. 2,963 mg/kgb. 6,667 mg/kgc. 2,963 microgram/mLd. 5.0 mg • Levofloxacin is a broad spectrum antibotic. It is reported that itis completely removed in an unchanged from the body and itselimination half life is 7 h. Determine the amount oflevofloxacin eliminated in urine at 10 h following IV bolusadministration of 6,25 mg/kg dose to a patient weighing 80 kg.a. 185,75 mgb. 314,25 mgc. 314,25 mg/kgd. 18,57 mgII Based on the image below, select the correct statement. Complex I Matrix arm NADH Fe-S FMN A 2e™ N-2 2e 2H+ NAD+ + H+ 4H+ QH₂ Intermembrane space (P side) Matrix (N side) Membrane arm https://canvas.uts.edu.au/assessment questions/356985/files/1562692/download? verifier=ePzpZHZuoVcemUMJXLgKrxl Rux2WcX3LR40FKWGq O Ubiquinone (Q) is oxidised to form Ubiquinol (QH2) O Ubiquinone (Q) is reduced to form Ubiquinol (QH2) O Electrons are transferred from FMN to NADH O Electrons are transfered from FMN to NAD+ O Electrons are transferred from Ubiquinone (Q) to Ubiquinol (QH2)
- Q28. An ABC transporter consists of two domains: the transmembrane domain (shown here as Y) and the ATP-binding cassette domain (shown here as Z). Which of the following statements correctly identifies a difference between these two domains? The hydropathy index is higher for Y than Z. Exchanging domain Y with domain Z would not affect the function. Exchanging domain Z with the same domain from a different ABC transporter will not alter the specificity of transport, but swapping Y domains will. Alpha helices are only found in the Y domain. A. 1,2 and 3 B. 1 and 3 C. 2 and 4 D. 4 only E. All of 1,2,3 and 4 are correctProblem. A 1-year-old child was admitted to the clinic with signs of damage to the muscles of the limbs and trunk. After the examination, carnitine deficiency in the muscles was revealed. Disruption of which transport process is the basis of this pathology? Explain the mechanism of this transport.Need help Ligaments and tendons are tissues whose response varies with time andexhibits rate dependent behavior under loading. What is the biomechanicalproperty of this response? Briefly describe and demonstrate this property by standard tests.
- BONUS QUESTION • In these lectures, we talked about two main things: levels of organization and homeostasis in physiological processes. This is a bonus task in which you are required to: 1) Sclect an example of homcostasis from human physiology. 2) List the homeostasis components of the system as elaborated in the lecture. 3) If you were to build a mathematical model of that system, what exactly do you need to measure/know? ** fecl free to use published papers as refcrences for your proposed model. ** your task submission need to contain a diagram of the physiological process or in the form of a presentation. This is a bonus task; however, you are highly encouraged to do it 20Question:- Explain why it makes sense for the PDH complex in liver to be active when dephosphorylated.Please ASAP. Thankyou. Question 5 You measure the membrane potential and find that it does not change from time X to time Y. However, you find that current across the membrane has increased by a factor of 4 from time X to time Y. Which of the following most likely happened between time X and Y? a. 4 times as many ion channels closed on the cell membrane b. Resistance of the membrane changed to ½ c, Resistance of the membrane changed to ¼ d. not enough information