Consider the following mechanism: What kind of reaction is occurring during this step of glycolysis? What metabolite is in Box 1? What metabolite is in Box 2? What metabolite is in Box 3? What enzyme catalyzes this reaction
Consider the following mechanism: What kind of reaction is occurring during this step of glycolysis? What metabolite is in Box 1? What metabolite is in Box 2? What metabolite is in Box 3? What enzyme catalyzes this reaction
Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)
8th Edition
ISBN:9781305634350
Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder
Chapter5: The Cardiovascular Sytem
Section: Chapter Questions
Problem 43LE
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Question
- Consider the following mechanism:
- What kind of reaction is occurring during this step of glycolysis?
- What metabolite is in Box 1?
- What metabolite is in Box 2?
- What metabolite is in Box 3?
- What enzyme catalyzes this reaction?
- Circle and label one place on the mechanism where covalent catalysis is occurring.
- Suggest an amino acid that could fill the role of residue “A” in the mechanism above and draw its structure at pH 7.4.
- Suggest an amino acid that could fill the role of residue “B” in the mechanism above and draw its structure at pH 7.4.
- Under standard conditions, this reaction is unfavorable (DG¢° = 23.8 kJ/mol). What conditions in the cell allow for the actual free energy change to be lower (DG » 0), making the reaction readily reversible? Explain your answer.
*please help and explain as well as you can*
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