Cell signaling- Describe the difference between quick vs. slow responses in cell signaling. Make sure you identify which one you are describing AND determine if the NGF pathway (NGF turns on Sprouty transcription) or the GPCR pathway (sperm binds egg to release Ca+) is an example of a quick vs a slow response.

Cell signaling- Describe the difference between quick vs. slow responses in cell signaling. Make sure you identify which one you are describing AND determine if the NGF pathway (NGF turns on Sprouty transcription) or the GPCR pathway (sperm binds egg to release Ca+) is an example of a quick vs a slow response.

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 1VCQ: Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is...

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Cell signaling in plant and animal cells is similar in those ways and different in others. Offer one or more hypotheses for these similarities and differences, and cite specific examples.
Part A (Short Response): You are developing a TGF-β agonist, but you don’t yet know which specific proteins it is signaling through. You want to do a single Western blot to measure changes in signaling activity, regardless of which pathway is being activated. For which protein involved in these pathways could you measure the levels in the nucleus of cells and be confident in your results? Why? This part was already posted on chegg, but I didn't understand the answer. I need a thorough explanation, so I can fully understand. Part B (Short Response): There have been many attempts to block TGF-β signaling in cancer through many different mechanisms, but none of been very successful. Why do you think this is? I know they have gotten close to being successful, but I don't know what preventing their success.
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Cell signaling in plant and animal cells is similar in some ways and different in others. What are some examples of this?
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Help constructing a concept map? Example provided below. Many studies have indicated that autophagy and apoptosis play an important role in the pathogenesis of spinal cord injury. In recent years, research on autophagy-related signal transduction pathways has demonstrated that the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway is closely associated with the initiation of autophagy. However, the mechanism of the pathological relationship between this signaling pathway and apoptosis in spinal cord injury is unclear. In this study, we used an in vitro model of spinal cord injury to observe the mechanism of the PI3K/Akt/mTOR signaling pathway and the apoptosis of neurons via the mitochondrial pathway. Mitochondrial pathway apoptosis-related proteins were detected by western blot. Akt and mTOR phosphorylation levels peaked 4 h after mechanical damage and then decreased. Following administration of the PI3K-specific…
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