Critically discuss the following statement: ‘The success of PARP inhibitor therapy in ovarian cancer has led to the development of novel synthetic lethal strategies targeting DNA damage response in solid tumours’. Include challenges of PARP inhibition therapy as well as future developments in your answer.

Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter24: New Technologies And Advances In Medical Instrumentation
Section: Chapter Questions
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Critically discuss the following statement: ‘The success of PARP inhibitor therapy in ovarian cancer has led to the development of novel synthetic lethal strategies targeting DNA damage response in solid tumours’. Include challenges of PARP inhibition therapy as well as future developments in your answer.

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