Below is a pedigree for a particular rare genetic disorder. It could be autosomal dominant, autosomal recessive, limited expression in females, limited expression in males, mitochondrial, reduced penetrance, sex- sex-linked dominant, or sex-linked recessive. • Recall this is a rare disorder. Propose the best fitting mechanism of inheritance. Justify your answer. • What are the genotypes of the individuals who marry into this family? Explain your answer.

Below is a pedigree for a particular rare genetic disorder. It could be autosomal dominant, autosomal recessive, limited expression in females, limited expression in males, mitochondrial, reduced penetrance, sex- sex-linked dominant, or sex-linked recessive. • Recall this is a rare disorder. Propose the best fitting mechanism of inheritance. Justify your answer. • What are the genotypes of the individuals who marry into this family? Explain your answer.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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