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- Using the cultured cells used in this experiment and described in the introduction, how would you approach determining the potency of an agonist to the D2 receptor?Define an opioid agonist, antagonist, mixed agonist-antagonist, and partial agonist. Give an example of each and how they are therapeutically useful.Explain in detail Muscarinic receptors in regards to the hisamine agonist. How do they cause smooth muscle contraction. Provide mechanism
- What are muscarinic antagonists? Explain the PharmacodynamicsDescribe the changes that occur in each step of the mechanism. (The probable mechanism of action of chymotrypsin)What type of drug do you consider DAMGO to be? Explain your answer and define terms such as agonist, antagonist, inverse agonist or partial agonist as appropriate for you answer
- In experiment，how would you approach determining the potency of an agonist to the D2 receptor？What is the maximum allowable dosage of the most commonly used anesthetic solution i.e. 2% Lidocaine HCl with 1:100,000 epinephrine for a healthy adult?What is the maximum allowable dosage of the most commonly used anesthetic solution i.e. 2% Lidocaine HCl with 1:100,000 epinephrine for a 52 kg healthy adult?