A pedigree is a useful diagram geneticists use to study genetic disorders and abnormalities within families. Which of the following pieces of information can best be discovered from a pedigree analysis? A The genotypic probabilities of the offspring. B The specific alleles produced by each parent. The genotypes of each parent and their offspring. D The pattern of inheritance of a particular gene.
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this is not biology its just basic science and pls if u help me don't write in cursive sorry I get confused when reading it
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- Eye Color is a trait that involves a number of genes. To simplify our example, we can break down the traitinto two phenotypes: dark color and light color eyes. Dark coloration is considered dominant, or isexpressed in a heterozygous condition (when the alleles are different).Q: If you have one light eyed parent and one parent that is homozygous for dark eye color, what are thepotential eye colors of their offspring (young)? To start, what do the Parents’ alleles look like? What istheir Genotype? (Remember, you pick which letter you want to use)Light eye colored parent:Dark eye colored parent:One of the things Mendel designed was a way to provide information about how the genes are passed onfrom parent to offspring. He designed something called a Punnett Square. This square places the parents’alleles outside the box, then uses those alleles to fill in the squares.Let’s start with a reminder of what we know about the parents: Parent Phenotype(appearance) Genotype(alleles) 1 2Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?
- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?Pedigree Analysis Is a Basic Method in Human Genetics Pedigree analysis permits all of the following except: a. an orderly presentation of family information b. the determination of whether a trait is genetic c. the determination of whether a trait is dominant or recessive d. an understanding of which gene is involved in a heritable disorder e. the determination of whether a trait is sex-linked or autosomalPedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?
- Which of the following statements describes the multifactorial inheritance in genetics? O Phenotype is determined by different environmental factors. O One locus is associated with variable phenotypes of a trait. Several loci are associated with the trait. One locus is associated with different traits. O Environment plays minimal or no role in the final phenotype.In Ayrshire cattle, thespotting of the animals can be either red and white or mahogany andwhite. The mahogany and white phenotype is caused by the allele SM.The red and white phenotype is controlled by the allele SR. The tablebelow shows the relationship between genotype and phenotype formales and females:Explain the pattern of inheritance.six small pedigrees are displayed. Indicate with J (yes) or N (No) if each pedigree is compatible with each of the following types of inheritance. Assume that the genetic characteristics are common in general population. Use table just like the table below in answering A B C D E F Autosomal Recessive Autosomal Dominant X-bound recessive X-bound dominant Y-Bottom
- Just for fun, imagine that "shirt-striping" is a phenotypic character caused by a single gene. Construct a genetic expla- nation for the appearance of the family in the above pho- tograph, consistent with their "shirt phenotypes." Include in your answer the presumed allele combinations for "shirt- striping" in each family member. Identify the inheritance pattern shown by the child.A sex-influenced trait in humans affects the length of the index finger. A short allele is dominant in males and recessive in females.Heterozygous males have an index finger that is significantly shorterthan the ring finger. The gene affecting index finger length is locatedon an autosome. A woman with short index fingers has childrenwith a man who has normal index fingers. They produce five children in the following order: female, male, male, female, male. Theoldest female offspring has one daughter with a man who has normal fingers. The youngest male among the five children has childrenwith a woman with short index fingers; they have two sons. Drawthe pedigree for this family. Indicate the phenotypes of every individual (filled symbols for individuals with short index fingers andopen symbols for individuals with normal index fingers)For Mendelian inheritance, the nuclear genotype (i.e., the allelesfound on chromosomes in the cell nucleus) directly influences anoffspring’s traits. In contrast, for non-Mendelian inheritance patterns, the offspring’s phenotype cannot be reliably predicted solelyfrom its genotype. For the following traits, what do you need toknow to predict the phenotypic outcome?A. Dwarfism due to a mutant Igf2 alleleB. Snail coiling directionC. Leber hereditary optic neuropathy