8. A patiènt sullering from infectious polyarthritis, has been receiving prednišone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showed a deerease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminished. Why did the patient's state worsen after he quitted this drug? For the answer: a) draw a flowchart of hormone synthesis and secretion for the hormone with inhibited production caused by the prolonged administration of prednisone; b) predict an improvement in the patient's state if he is given corticotropin; c) name the reasons for the blood glucose concentration and 17-ketosteroids decrease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped; d) substantiate the prednisone use to treat arthritis.

8. A patiènt sullering from infectious polyarthritis, has been receiving prednišone for a long time as treatment. Prednisone is a structural analogue of cortisol. As the patient felt better, he deliberately stopped taking this drug. Soon the patient's state took a dramatical turn for the worse. Screening showed a deerease in the patient's blood glucose concentration, the blood pressure dropped, and the content of 17-ketosteroids in the urine was diminished. Why did the patient's state worsen after he quitted this drug? For the answer: a) draw a flowchart of hormone synthesis and secretion for the hormone with inhibited production caused by the prolonged administration of prednisone; b) predict an improvement in the patient's state if he is given corticotropin; c) name the reasons for the blood glucose concentration and 17-ketosteroids decrease and blood pressure decline; write the metabolic pathway with its decreased rate in the liver when prednisone administration was stopped; d) substantiate the prednisone use to treat arthritis.

Understanding Nutrition (MindTap Course List)

15th Edition

ISBN:9781337392693

Author:Eleanor Noss Whitney, Sharon Rady Rolfes

Publisher:Eleanor Noss Whitney, Sharon Rady Rolfes

Chapter1: An Overview Of Nutrition

Section: Chapter Questions

Problem 1BCTQ

See similar textbooks

Similar questions

Metformin is contraindicated in all of the following situations, except:A. Increased BMIB. Tendency to develop lactic acidosisC. Diarrhea and other gastrointestinal disturbancesD. PregnancyE. Breast feeding
One of the indications for prescribing nateglinide is:A. Depletion of pancreatic beta-cellsB. Significant postprandial hyperglycemiaC. Tendency to develop lactic acidosisD. Resistance to sulfonylureasE. Insulin resistance
Dexamethasone 1 Dexamethasone is a glucocorticoid administered as an anti-inflammatory agent and immunosuppressant. It is structurally similar to cortisol produced naturally by your adrenal glands. It treats a number of conditions including inflammation, arthritis, autoimmune conditions, skin and eye conditions, asthma, multiple sclerosis, blood or bone marrow disorders, different types of cancer (e.g. leukemia and lymphoma), and severe allergies. This medication is also administered to patients with severe COVID-19 symptoms to decrease mortality rates*. Given that it is a steroid, which family of macromolecules does dexamethasone belong to? *research from the University of Oxford, "Randomised Evaluation of COVID-19 Therapy" trial, recovery.net 2 Given the structures of dexamethasone (left) and cortisol (right) below, and that they both bind to the same receptor, would you expect the binding of dexamethasone to be to the active or allosteric site of the receptor? 3 Based on the…
10. A prescriber sends the following prescription for insulin:“Inj. 30 units QAM ā breakfast, 20 units ā lunch, and 20 units ā supper.”How many 3-mL vials of Humalog U-200 should be dispensed if a 28 day supply is to be dispensed? Round UP to the nearest vial
2) prednisone 35mg is or dered This mes.catiun comes in 5mg tablets How many Pills do you give?
6. The client has progressed to a regula diet and is ordered Humulin N 13 unit and Humulin R 6 units subcutaneous 30 minutes ac breakfast, and Humulin N 5 units and Humulin R 5 units subcuta- neous 30 minutes ac dinner. a. How many units will the client re- ceive before breakfast? b. Indicate on the appropriate syringe given the number of units of each insulin required before breakfast. SIINI
"hich of the following statements is true of the differences between methohexital and midazolam? Multiple Choice Midazolam produces analgesia at small doses whereas methohexital produces amnesia at anesthetic doses. Midazolam induces anesthesia quickly, but methohexital does not. Methohexital has a specific receptor antagonist but midazolam does not. Midazolam is available for rectal administrątion, whereas methohexital is administered intravenously.
The main cause of death in relation to opioids poisoning is: Hypertension Severe dehydration O Brain hemorrhage Respiratory depression
II. Apatient cametoatherapist with complaintsofprogressive weakness, drowsiness, dizziness. Symptoms were intensifying during fasting that allowed the doctor to suggest hypoglycemia in the patient. Additional screening (glucose level was less than 2.5 mmol/A, C-peptide level significantly increased) confirmed the initial assumption. The patient does not suffer from diabetes and does not take sugar-lowering drugs. What possible cause of the disease can be assumed in the patient? What hormone seeretion is increased in such patient? What is the danger of hypoglycemia? What processes in the body prevents the hypoglycemia even during fasting in healthy person?
5. List the steps for mixing a short acting and long acting insulin in the same syringe.
3.On clinical examination of54-year-old woman the tumor of adrenal cortex was revealed. The glucoselevel in blood was increased. What is the main cause of hyperglycemia in this case? For answer:a)indicatethe hormone, which is elevated in the blood of patient;b)discuss this hormone synthesis and themechanism of signal transduction in target tissues; c)describe the metabolic pathways can be stimulated by this hormone in liver.
Aspirin can alleviate clinical because it inhibits the synthesis of certain eicosanoids. True O False