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- Which of the following is a positive inotrope?a. Na+b. K+ c. Ca2+d. both Na+ and K+Which of the following is a positive inotrope?a. Na+b. K+c. Ca2+d. both Na+ and K+Which of the following statements about Ca2+ handling in cardiac contractile cells is FALSE? a. One Ca2+ spark is sufficient to cause cross bridge cycling b. When Ca2+ ions flow out of the sarcoplasmic reticulum and into the cytosol, they create a Ca2+ spark c. Ca2+ released from the SR provides ~80% of the Ca2+ needed for muscle contraction d. Summed Ca2+ sparks from different RyR channels create a Ca2+ signal sufficient to cause cross bridge cycling e. Ca2+ sparks can be visualised using biochemical methods
- Which of the following is true about the pacemaker potential in the heart? a. Decreased K+ efflux causes the resting membrane potential to increase b. Action potential occurs when T-type Ca2+ channels open c. Only the SA node in the heart has a pacemaker potential d. The atrioventricular node is needed to pace the sinoatrial node e. None of the options are trueWhich of the following is a positive inotrope? a. Na+ b. К+ с. Са2+ d. both Na+ and K+a calcium channel blocker or an antagonist drug will produce a. vasoconstriction b. increase in blood pressure c. increase in total peripheral resistance d. reduction in cardiac muscle contractility
- Define the following terms: a. AMPK b. ACP c. SREBP d. PPAR e. atherosclerosiswhy are cardiac muscle cells affected by hyperkalemia? A. All choices below are correct B. Resting membrane potential becomes less negative C. Voltage across the cardiac muscle cell cannot be maintained D. The cardiac muscle cell cannot respond to a nerve stimulusWhich of the following statements is (are) true concerning the pathways for blood clotting?a. The intrinsic pathway takes less time than the extrinsic pathway.b. The intrinsic and extrinsic pathways require sodium.c. The intrinsic pathway is started by factors from damaged tissues.d. The intrinsic pathway requires the same clotting factors as the extrinsic pathway.e. The common pathway results in fibrin changing to fibrinogen
- Which cell types are associated with spontaneous action potential generation in the absence of an external stimulus from other tissues. A. Sino-Atrial node cells (SA node). B. Atrial cells C. Ventricular cells. D. Endothelial cells. E. A and D.As bicarbonate ions attach to erythrocytes, the balance between positively and negatively charged ions is disturbed, causing the chloride shift. As the bicarbonate ions leave the erythrocyte, there is a decrease in the negative charge, which is relieved by the diffusion of Cl- into the erythrocytes. a. Both statements are correct b. Both statements are incorrect c. First is correct; Second is incorrect d. First is incorrect; Second in correctA patient is admitted to the ER complaining of chest pains and difficulty breathing. He states that the chest pain began two days ago and that the difficulty breathing started a few hours ago. Which of the following cardiac markers would be useful to determine if this patient had a myocardial infarct? a. Myoglobin b. СК-МB c. Troponin I d. BNP