1. Please consider the following pedigree. I 2 II 1 2 a) Assume that colour is controlled by a single sex-influenced gene where orange is expressed preferentially in males. Individuals I-1 and I-2 are homozygous for blue and orange respectively. Which individual/s in generation II will be blue? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be orange?

1. Please consider the following pedigree. I 2 II 1 2 a) Assume that colour is controlled by a single sex-influenced gene where orange is expressed preferentially in males. Individuals I-1 and I-2 are homozygous for blue and orange respectively. Which individual/s in generation II will be blue? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be orange?

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter13: Genes, Chromosomes, And Human Genetics

Section: Chapter Questions

Problem 8TYK: Another gene in Drosophila determines wing length. The dominant wild-type allele of this gene...

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1. Please consider the following pedigree. I 1 2 II 1 a) Assume that colour is controlled by a single sex-influenced gene where orange is expressed preferentially in females. Individuals I-1 and I-2 are homozygous for orange and blue respectively. Which individual/s in generation II will be blue? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be orange?
a) Assume that colour is controlled by a single sex-influenced gene where green is expressed preferentially in males. Individuals I-1 and I-2 are homozygous for red and green respectively. Which individual/s in generation II will be red? b) If colour is a controlled by cytoplasmic DNA, which individual/s in generation II will be green?
11. In Drosophila, three autosomal genes have the following map 5 m.u. 10 m.u. b + When a+ b+ c+ abc females are crossed to a bclabc males, how many flies of the phenotype a+ b c+ is expected among 1000 progeny assuming interference of 60%? A) 1 B) 2 C) 5 D) 3 E) 10
a. In Drosophila, crosses between F1 heterozygotes ofthe form A b / a B always yield the same ratio ofphenotypes in the F2 progeny regardless of the distance between the two genes (assuming completedominance for both autosomal genes). What is thisratio? Would this also be the case if the F1 heterozygotes were A B / a b? (Hint: Remember that inDrosophila, recombination does not take placeduring spermatogenesis.)b. If you intercrossed F1 heterozygotes of the formA b / a B in mice, the phenotypic ratio among the F2progeny would vary with the map distance betweenthe two genes. Is there a simple way to estimate themap distance based on the frequencies of the F2phenotypes, assuming rates of recombination areequal in males and females? Could you estimatemap distances in the same way if the mouse F1heterozygotes were A B / a b?
1. The pedigree below shows the incidence of rare, autosomal dominant disorder called Ehlers-Danlos disease. The pedigree covers three generations of a particular family and also shows individual genotypes at a potential marker locus (M). a) Indicate the phase of all gen II and III individuals. DdM1M3 ddM2M6 II DDM3M6 ddM4M5 III DdMзM4 DdMЗМ5 DDM3M4 ddM3M5 DDM3M4 ddM5M6 DDM3M4 ddM4M6 ddM5M6 ddM5M6 b) Which, if any, of the gen III individuals are recombinants? c) Calculate the LOD score as a test of physical linkage between the marker (M) and the disease locus. d) What do you conclude about linkage between D and M?
1. The allele G for yellow stigma is completely dominant to green (g). Supposingtwo strains of autotetraploid plants are available and their genotypes are as follows:GGgg – in this plant the gene is close to the centromereGggg – in this plant the gene is far from the centromere If these two plants are crossed:a) provide the gametes that can be obtained from the two plants;b) provide the genotypic and phenotypic ratios of the offspring. 2. Consider the illustration below. Diagram the configuration you would observe at Anaphase I if crossing-over happens within the inversion. (IMAGE ATTACHED)
1. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) X- linked recessive and b) X-linked dominant in order to determine what is the mode of transmission of this trait. Disease allele = XA or Xa, depending on mode of transmission of the disease respectively. *Unaffected/No carrier-Normal Unaffected X chromosome = X I 11 * 1 2 1 2 3 a) X-linked recessive 11x12 III 2 genotype (circle one): XY 4 XAXA 2 3 5 Xaya *4 6 7 8 b) X-linked dominant 11x12 XAY Xay
A mutant sex-linked trait called “notched” (N) is deadly in Drosophila when homozygous in females. Males who have a single N allele will also die. The heterozygous condition (Nn) causes small notches on the wing. The normal condition in both male and females is represented by the allele n. a) Indicate the phenotypes of the F1 generation from the following cross: XNXn x XnY b) Explain why dead females are never found in the F1 generation no matter which parents are crossed. c) Explain why the mating of female XNXn and a male XNy is unlikely.
In Drosophila melanogaster, red eyes are dominant over white and the variation for this characteristic is on the X chromosome. Vestigial wings (v) are recessive to normal (V) for an autosomal gene. Predict the appearance of offspring of the following crosses: XW/Xw V/v×Xw/Y v/v, Xw/Xw V/v × XW/Y V/v.
Another gene in Drosophila determines wing length. The dominant wild-type allele of this gene produces long wings; a recessive allele produces vestigial (short) wings. A female that is true- breeding for red eyes and long wings is mated with a male that has purple eyes and vestigial wings. F1 females are then crossed with purple-eyed, vestigial-winged males. From this second cross, a total of 600 offspring are obtained with the following combinations of traits: 252 with red eyes and long wings 276 with purple eyes and vestigial wings 42 with red eyes and vestigial wings 30 with purple eyes and long wings Are the genes linked, unlinked, or sex-linked? If they are linked, how many map units separate them on the chromosome?
IN DROSOPHILA, AN X-LINKED RECESSIVE MUTATION, Xm CAUSES MINIATURE WINGS. LIST THE F₂ PHENOTYPIC RATIOS IF: A MINIATURE-WINGED FEMALE IS CROSSED WITH A NORMAL MALE AND A MINIATURE-WINGED MALE IS ● ● CROSSED WITH A NORMAL FEMALE. WHAT WOULD THE PHENOTYPIC RATIO FROM (A) BE IF THE MINIATURE- WINGED GENE WERE AUTOSOMAL? ASSUME IN ALL CASES THAT THE P1 INDIVIDUALS ARE TRUE-BREEDING.
Here is a family pedigree for an imprinting disorder caused by a loss of function mutation in a single imprinted gene. After generation I only related individuals are shown. You can assume that the parents not included in the pedigree did not carry the mutation. %3D II IV V Male O Female Affected Carrier a) Does the mutation involve a gene that is normally expressed from the maternal or from the paternal allele? Briefly explain your logic. b) Identify two ways in which the pattern of inheritance shown in the pedigree is different from X-linked inheritance I. Parthenogenesis has been documented in most vertebrate Classes (e.g. birds, fish) but never in mammals. Genomic imprinting provides one explanation for this observation. Why?