#1. Part A. in a drug discovery program, a hit compound________. A. Shows activity in an animal model of disease B. Is active in target/ whole-cell assays in vitro C. Is purchased from a commercial vendor D. Is derived from screening natural product libraries Part B. When using TLC to monitor an organic chemistry reaction, which could be an indication that your desired reaction has gone to completion? A. the stationary phase changes colors B.the mobile phase runs to the top of the tlc plate C.the starting material spot disappears and a new spot appears D,the starting material spot remains on the tlc plate

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter1: Introduction
Section: Chapter Questions
Problem 1.12QAP
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#1.

Part A.

in a drug discovery program, a hit compound________.

A. Shows activity in an animal model of disease

B. Is active in target/ whole-cell assays in vitro

C. Is purchased from a commercial vendor

D. Is derived from screening natural product libraries

Part B.

When using TLC to monitor an organic chemistry reaction, which could be an indication that your desired reaction has gone to completion?

A. the stationary phase changes colors

B.the mobile phase runs to the top of the tlc plate

C.the starting material spot disappears and a new spot appears

D,the starting material spot remains on the tlc plate

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