Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm ( FIGURE 4.20 ) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations. FIGURE 4.20 An effect of Kartagener syndrome . Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).

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Answer 1

Textbook Question

Chapter 4, Problem 1DAA

Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm (FIGURE 4.20) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations.

Chapter 4, Problem 1DAA, Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener

FIGURE 4.20 An effect of Kartagener syndrome. Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 2

Textbook Question

Chapter 4, Problem 1DAA

Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm (FIGURE 4.20) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations.

Chapter 4, Problem 1DAA, Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener

FIGURE 4.20 An effect of Kartagener syndrome. Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 3

Textbook Question

Chapter 4, Problem 1DAA

Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm (FIGURE 4.20) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations.

Chapter 4, Problem 1DAA, Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener

FIGURE 4.20 An effect of Kartagener syndrome. Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 4

Textbook Question

Chapter 4, Problem 1DAA

Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm (FIGURE 4.20) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations.

Chapter 4, Problem 1DAA, Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener

FIGURE 4.20 An effect of Kartagener syndrome. Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

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Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 8

Expert Solution & Answer

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To explain: The observations regarding the effect of the Kartagener syndrome causing male infertility.

Introduction: Kartagener syndrome is an autosomal recessive genetic condition characterized by the ciliary motility disorder. Cilia are hair-like structures lining the mucus membranes of the nose, lungs, and sinuses. In Kartagener syndrome, the cilia do not move properly and defects are found in the dynein (component of cilia) arms. This results in the abnormal morphology of the sperm tails and bronchial cilia.

Answer 12

Explanation of Solution

Refer to Fig. 4.19, “How eukaryotic flagella and cilia move” in the textbook. Flagella and ciliary movements are provided by the motor protein dynein attached to the nine microtubules arranged in a circle. Abnormality in the dynein arms causes Kartagener syndrome. Refer to Fig. 4.20, “An effect of the Kartagener syndrome” in the textbook. The lack of the dynein arms result in the abnormal morphology of the sperm tails and bronchial cilia causing lung infections, chronic sinus, and infertility. Men with Kartagener syndrome are infertile but they produce sperms. They are infertile because the defected dynein would affect the movement of the flagella and cilia. As a result, there would be abnormal sperm motility and it would not be able to swim normally for fertilization.

Answer 13

Ch. 4 - Effects of Kartagener Syndrome An abnormal form of...Ch. 4 - All cells have these three things in common:...Ch. 4 - Which of the following is,not a principle of the...Ch. 4 - The surface-to-volume ratio _______. a. does not...Ch. 4 - A plasma membrane ________. a. controls exchanges...Ch. 4 - True or false? Ribosomes are only found in...Ch. 4 - Unlike eukaryotic cells, prokaryotic cells ______....Ch. 4 - What controls the passage of molecules into and...Ch. 4 - The main function of the endomembrane system is:...Ch. 4 - Enzymes. contalned in _______ break down worn-out...

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