Answered: Would the viral insertion of a…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Would the viral insertion of a proto-oncogene into a region of genomic DNA with non-acetylated histones be likely to lead to a cancerous cell? Explain. (Read the answer options VERY carefully!)

A. NO it would not lead to a cancerous cell. Non-acetylated histones = condensed chromatin so viral insertion here means there would be no transcription so this would not increase levels of the protein.

B. NO it would not lead to a cancerous cell. Non-acetylated histones = open chromatin so viral insertion here means there would be high levels of transcription and this would increase the levels of the protein

C. YES it would lead to a cancerous cell. Non-acetylated histones = condensed chromatin so viral insertion here means there would be no transcription so this would not increase levels of the protein.

D. YES it would lead to a cancerous cell. Non-acetylated histones = open chromatin so viral insertion here means there would be high levels of transcription and this would increase the levels of the protein

E. Not enough information

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