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31. “Wnt”is a regulatory factor that regulate myogenic stem cell proliferation?
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True |
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False |
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Solved in 2 steps
- 1) Briefly outline the location, isolation , characterisation, benefits, and limitations of adult stem cells in TERM 2) Describe and compare the various potencies exhibited by stem cell pheno type 3) Outline the in vitro/in vivo mechanical forces that can be used to influence the quality of cell response and tissue formation obtained by TE..iPSCs are derived from differentiated cells that are further differentiated into a stem cell state. True or false?List the regulatory mechanisms that might be lost in a cell producing faulty p53.
- Which of the following structures could be found within the nucleolus?How does PKC’s signaling role change in response to growth factor signaling versus an immune response? PKC interacts directly with signaling molecules in both cascades, but only exhibits kinase activity during growth factor signaling. PKC interacts directly with signaling molecules in growth factor cascades, but interacts with signaling inhibitors during immune signaling. PKC amplifies growth factor cascades, but turns off immune cascades. PKC is activated during growth factor cascades, but is inactivated during immune response cascades.''In the cellular regulatory pathways that controlcell growth and proliferation, the products of oncogenesare stimulatory components and the products of tumorsuppressor genes are inhibitory components.'' 'Is this statement true? Explain why or why not.
- why EGFR play a role in CRC and other cancer?Why do cancer cells undergo EMT and MET? What are the cellular changes (expression or suppression of molecules) associated with EMT and MET? What does each change facilitate?Describe the effects of the over-expression of mdm2 on cell proliferation and apoptosis on cell signaling pathways and metabolism or cell cycle control. Briefly explain the normal role of each component in the context of the pathway and why its loss or modification would have the expected effect.
- Myostatin is termed a negative growth regulator. Explain themeaning of this term, and describe the consequences of genemutations that cause myostatin to be nonfunctional.Changes in the activity of a variety of Cdks are essential for accurate progression through the cell cycle, and yet the levels of Cdk expression are fairly constant during the cell cycle. Briefly describe three mechanisms by which the activity of Cdks is regulated.Long non-coding RNAs (lncRNA) can act as a scaffold to form protein/RNA complexes that regulate gene expression? True False Wnt is a regulatory factor that regulate myogenic stem cell proliferation? True False
