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Why diabetes mellitus is associated with polidypsia, polyphagia and polyuria? How common is gestational diabetes? How can it be diagnosed?
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- Which of the following best describes the role of the hexosamine pathway in the pathogenesis of the chronic complications of diabetes mellitus? Question 79 options: a) It involves irreversible binding of glucose to proteins, lipids and nucleic acids which damages components of the microcirculation leading to retinopathy, etc. b) It promotes the O-linked glycosylation of proteins and transcription factors, resulting in altered gene expression contributing to insulin resistance & cardiovascular complications c) It promotes the synthesis of DAG which increases pro-inflammatory gene expression and endothelial ET-1 production resulting in blood flow abnormalities d) It leads to intracellular accumulation of osmotically active sorbitol and fructose which damages Schwann cells, erythrocytes and the lens of the eyeWhat is Diabetes Mellitus?How and why does it occur?Explain the cause of hypothyroidism ?
- Which of the following is considered a microvascular complication of diabetes mellitus? options: a) Nephropathy b) Coronary artery disease c) Cerebral vascular accident d) Peripheral vascular diseaseIdentify the cause of each of the following conditions: diabetes insipidus, pituitary dwarfism, gigantism, acromegaly,Cushing syndrome, and Addison disease.Describe the cause for the following diseases: Pituitary dwarfism, Diabetes mellitus, Graves' disease, Addison’s disease