Q: Why does heat denature, or melt, DNA in solution?
A: DNA or deoxyribonucleic acid is the genetic material of most of the organisms except RNA viruses. It…
Q: In the Meselson–Stahl experiment thatestablished the semiconservative nature of DNA replication,the…
A: Replication follows the semiconservative mode, which was proved by the experiment conducted by…
Q: Is it biologically possible for DNA to undergo replication in vivo, without the lagging and the…
A: Introduction When the DNA chromosome is replicated, two copies of each identical daughter cell are…
Q: HOW DO WE KNOW THAT DNA REPLICATION IS SEMICONSERVATIVE? MESELSON-STAHL EXPERIMENTS
A: DNA replication in all known cells is described as semiconservative replication. Along the DNA…
Q: What is the completing sequence of nitrogen- containing bases for a AGCCGTTAAC fragment of a DNA…
A: DNA base pairs are due to the formation of hydrogen bonds between the nitrogenase bases, purines,…
Q: Which Strict Operating Requirements DNA Polymerase Has?
A: DNA polymerase is an enzyme involved in the synthesis of nucleotides. These are important for the…
Q: Why were Meselson and Stahl unable to distinguish between the dispersive and the semiconservative…
A: Replication is the process of synthesising the new strand from the parent strand.
Q: Why does replication process struggle with repetitive sequence - and how does this impact a certain…
A: Genomes containing lots of repetitive sequences like the human genome create difficulties with…
Q: Describe why the structure of DNA led Watson and Crick to point out “apossible copying mechanism for…
A: Introduction DNA strand is composed of three components: Deoxyribose Sugar Nitrogenous Bases…
Q: How did the results prove the semiconservative model of DNA replication? Explain.
A: The above experiment is cesium chloride density gradient centrifugation. This experiment was done by…
Q: What evidence did Watson and Crick have at their disposal in 1953? What was their approach in…
A: A biomolecule that consists of multiple polynucleotide chain and is inherited within generations is…
Q: If DNA polymerase requires a perfectly pairedprimer in order to add the next nucleotide, how is it…
A: DNA polymerases are enzymes that manufacture DNA molecules by assembling nucleotides, which are the…
Q: Escherichia coli (E. coli) has one replication origin that contains specific genomic sequences…
A: DNA replication It is defined as the process through which the copying of DNA takes place in cells.…
Q: If hypoxanthine (structure shown) was incorporated into double stranded DNA, what would it most…
A: Hypoxanthine is a non-natural base that is found in the DNA. DNA is also known as deoxyribonucleic…
Q: Provide a chemical explanation of why DNA synthesis proceeds in a 5'- to-3' direction.
A: The genes are the hereditary unit of an organism which are passed on from the parental generation to…
Q: The sequence of the 15 bp fragment from the previous problem is repeated below: 5' TCTGAATTCCGTAGA…
A: DNA is a double-stranded molecule that is made of several nitrogen base pairs. The nitrogen base of…
Q: Explain why the bending of the double helix to form a superhelix falls into the area of geometry or…
A: Nucleic acids are important biomolecules. Nucleic acids are of two types. These are DNA…
Q: What background information did waston and crick have made availale for developing a model of DNA?…
A: DNA (deoxyribonucleic acid) is the genetic material for the majority of organisms. Nucleic acids are…
Q: Is it unusual that the β-subunits of DNA polymerase III that form a sliding clamp along the DNA do…
A: DNA pol II is the primary enzyme involved in DNA replication. It is a mutiprotein complex that…
Q: Explain why DNA replication requires RNA primers. What do they do and why do they have to be…
A: The process of duplicating a double-stranded DNA molecule into two identical DNA molecules is known…
Q: Suppose Meselson and Stahl had done theirexperiment the other way around, starting with cells fully…
A: Introduction: Meselson and Stahl conducted an experiment with the E.coli DNA which proved the…
Q: Explain how the Meselson-Stahl experiment with heavy nitrogen showed that DNA replication is…
A: The DNA (deoxyribonucleic acid) is known to store the genetic information of an organism. The DNA is…
Q: What background information did Watson and Crick had available with them for developing a model of…
A: The following knowledge was available to Wastson and Crick, which aided them in developing a DNA…
Q: If a bacterial (E. coli) cell has 50,000 bp, how long will be a normal DNA replication?
A: Different macromolecules are present in the body, and they include carbohydrates, proteins, lipids,…
Q: An investigator obtalns a bacterial temperature-sensitive mutation that affects a step in the…
A: DNA (deoxyribonucleic acid) was discovered by Friedrich Miescher. Nucleotides are the structural…
Q: Show the watson-crick model for semoconservative DNA replication?
A: We know that, DNA is the largest macro molecule that represents the genetic material of the cell.…
Q: Kornberg showed that nucleotides are added to the 3' end of eachgrowing DNA strand. In what way does…
A: It is majorly present within the nucleus. DNA can exist in different levels of complexity. Primary…
Q: DNA polymerases cannot initiate DNA synthesis without a primer, a section of nucleic acid having a…
A: Primase is an RNA polymerase which produce short strand of primer required by DNA polymerase in DNA…
Q: In the early 1950s, it became clear to many researchers that DNAwas the cellular molecule that…
A: DNA ( deoxyribonucleic acid) is the genetic material that the organism inherits from the parental…
Q: Which positions in the purine ring of a purine nucleotide in DNAhave the potential to form hydrogen…
A: DNA is the chemical name for the molecule that carries genetic instruction is all living things. The…
Q: Which would require a higher temperature to denature—a DNA strand composed primarily of A-T base…
A: DNA. It is a long chain of polynucleotides. The DNA contain four bases 1. Adenine 2. Guanine 3.…
Q: What is generated from the replication of DNA ? what method is used ? Describe the process. What are…
A: The process of DNA replication is one of the first processes that is described in the central dogma.…
Q: List the differences and similarities in the way the twodaughter strands of DNA are synthesized at a…
A: DNA (deoxyribonucleic acid) is the genetic material of almost all living organisms. It is a double…
Q: What features of the structure of DNA enable it to be replicated?
A: Biomolecules are organic compounds found in living organisms. Examples of biomolecules includes…
Q: Explain watson-crick model for semiconservation DNA replication?
A: Introduction DNA replication is very crucial for the continuation of life as every new daughter…
Q: How many bands of DNA would be expected in Meselson and Stahl’s experiment after two rounds of…
A: Meselson and Stahl’s experiment: This experiment proves the nature of DNA replication by using the…
Q: How did the results prove the semiconservative model of DNA replication? Explain
A: To obtain heavy density DNA, Meselson and Stahl cultured bacteria in a N15 medium. This result…
Q: Would you expect to find nuclear localization sequences(NLSs) in the proteins that make up…
A: A nuclear localization sequence is an amino acid sequence that aids in protein transport (import)…
Q: Why Sanger sequencing uses ddNTPs and how they differ functionally from dNTPs. Does Sanger…
A: Sanger sequencing is the method of sequencing (determining the sequence of DNA) of DNA using the…
Q: . Why is DNA replication slightly slower in the lagging strand of DNA than in the leading strand?…
A: Leading strand is the parent strand of DNA which runs in the 3' to 5' direction toward the fork, and…
Q: Human cells have approximatelly 6,000,000,000 base pairs. How many errors per replication occur?
A: Human cells have approximatelly 6,000,000,000 base pairs. How many errors per replication occur?…
Q: Why are primers required in DNA replication but not in transcription
A: DNA replication is a process that takes place inside the nucleus of the cell. During replication the…
Q: Chargaff determined the base composition of DNA from a variety ofdifferent sources.What information…
A: Introduction DNA is the genetic material whose structural unit is nucleotides. Each nucleotide…
Q: Describe the DNA helix proposed by Watson and Crick
A: The double-helix model of DNA is confirmed by Watson and Crick in the year 1953, It is called the…
Q: . What information about the structure of DNA wasobtained from X-ray crystallographic data?
A: The deoxyribonucleic acid (DNA) is a hereditary material that is found in almost all living…
Which property of DNA double helix led Watson and Crick to hypothesise
semi-conservative mode of
Step by step
Solved in 2 steps
- Describe why the structure of DNA led Watson and Crick to point out “apossible copying mechanism for the genetic material.”X-ray was used by Rosalind Franklin and Maurice Wilkins to study the molecular structure of DNA. Why is their finding not accepted by Watson and Crick? Explain.Show the watson-crick model for semoconservative DNA replication?
- What did the Watson–Crick model suggest about the replication of DNA?Explain watson-crick model for semiconservation DNA replication?In the Meselson–Stahl experiment thatestablished the semiconservative nature of DNA replication,the extraction method produced short fragments of DNA. Whatsort of results might have been obtained with longer piecesof DNA?
- Watson and Crick used an approach called model building to deduce the structure of the DNA double helix.How does this differ from the more conventional experimental approach that is undertaken in a research laboratory? In this regard, why was the experiment of Meselsonand Stahl considered to be of such critical importance?State the properties of the WatsonCrick model of DNA in the following categories: a. number of polynucleotide chains b. polarity (running in same direction or opposite directions) c. bases on interior or exterior of molecule d. sugar/phosphate on interior or exterior of molecule e. which bases pair with which f. right- or left-handed helixHow did the results prove the semiconservative model of DNA replication? Explain.
- Describe the DNA helix proposed by Watson and CrickWould you expect to find nuclear localization sequences(NLSs) in the proteins that make up prokaryotic and eukaryotic DNA and RNA polymerases? Explain why orwhy notIn the early 1950s, it became clear to many researchers that DNAwas the cellular molecule that carries genetic information. However,an understanding of the genetic properties of DNA couldonly be achieved through a detailed knowledge of its structure.To this end, several laboratories began a highly competitive raceto discover the three-dimensional structure of DNA, which endedwhen Watson and Crick published their now classic paper in 1953.Their model was based, in part, on an X-ray diffraction photographof DNA taken by Rosalind Franklin (Figure 9.10). Two ethical issuessurround this photo. First, the photo was given to Watson and Crickby Franklin’s co-worker, Maurice Wilkins, without her knowledge orconsent. Second, in their paper, Watson and Crick did not creditFranklin’s contribution. The fallout from these lapses lasted fordecades and raises some basic questions about ethics in science. What vital clues were provided by Franklin’s work to Watsonand Crick about the molecular structure…