What is unique about blood flow out of the glomerular capillaries (Hint: what vessel drains them)? How does this help to explain why the pressure in the glomerular capillaries is higher than other capillaries?
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What is unique about blood flow out of the glomerular capillaries (Hint: what vessel drains them)? How does this help to explain why the pressure in the glomerular capillaries is higher than other capillaries?
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- Why does the glomerulus have a high-pressure capillary network? Explain.Why may a larger volume of fluid move across the glomerular membrane than across the membrane of other capillaries?What is the difference between the glomerular capillaries and the peritubular capillaries? How do these relate to afferent and efferent arterioles? Why do the efferent arterioles have oxygenated blood? (The answer isn’t “they are called arterioles, therefore they have oxygenated blood.)
- Why is there much greater filtration through glomerular capillaries than through capillaries elsewhere in the body?What mechanism ensures that blood pressure at the glomerulus is higher than in a tupical capillary bed?Pressure in the renal artery is 100 mm Hg and the pressure in the renal vein is 50 mm Hg. The resistance of the afferent arteriole equals 0.5 mm Hg•min/L and the resistance of the efferent arteriole equals 0.5 mm Hg•min/L. What is the pressure in the glomerulus?
- Describe the pathway of blood flow through the kidney from the abdominal aorta to the inferior vena cava.Explain the role of renin-angiotensin - aldosterone pathway in restoring blood pressure and fluid balance. Include the stimulus for release, the pathway that is involved, and the physiological effects of angiotensin II and aldosterone. Answer should include: Identify stimulus/change that starts the pathway (i.e. Identify the direction of change IN BP or circulating fluid status) What happens in the juxtaglomerular cells? Clue: what stimulus causes the release of renin? Explain action of renin - what protein does it act on? What is it converted to? Which enzymes converts angiotensin 1 to angiotensin 2? What are the actions of angiotensin 2? Clue: stimulates adrenal context to produce what? And what effect does angiotensin 2 have on blood vessels? What causes reabsorption of Na into blood ? What effect does this have on blood volume? How is BP restored ? Explain how this relates to equation for BP ( BP= CO x TPR)The glomerulus differs from other capillaries in the body in that it Question options: a) is impermeable to most substances c) has a blood pressure much higher than other capillaries e) has a basement membrane
- Describe the two capillary beds through which blood must pass in the kidney.Is this following statement correct? In the kidney, vasoconstriction of the afferent arteriole increases glomerular filtration rate, because hydrostatic pressure in the glomerular capillaries increases (much like putting your thumb over the end of a garden hose increases the pressure and causes the water to exit the hose with greater velocity and travel a greater distance).Explain the anatomical features that create high glomerular capillary blood pressure and explain why this blood pressure is significant for urine formation.